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Product Name: Trifluoperazine Hydrochloride
Chemical Formula: C21H24F3N3O2S·HCl
CAS Number: 440-17-5
Molecular Weight: 494.96 g/mol
Synonyms: Stelazine Hydrochloride, Trifluoperazine dihydrochloride
Product Use: Antipsychotic medication used mostly in treatment of schizophrenia and anxiety
Manufacturer: Specific details based on supplier
Emergency Contact: Poison Control Center or local emergency services
Hazard Class: Toxic if swallowed, irritating to eyes, skin, and respiratory system
GHS Label Elements: Danger, skull and crossbones, exclamation mark
Signal Word: Danger
Health Hazards: Exposure leads to nausea, dizziness, CNS effects, extrapyramidal symptoms, allergic reactions
Environmental Hazards: Harmful to aquatic life with long-lasting effects
Physical Hazards: Not classified as flammable or explosive, but dust may cause irritation
Chemical Name: Trifluoperazine Hydrochloride
Concentration: 100% pure, as supplied, or as listed by the manufacturer
Impurities / Additives: None unless specified by batch certificate
Other Components: No known significant non-hazardous ingredients
Inhalation: Remove victim to fresh air, keep at rest, seek immediate medical attention
Skin Contact: Remove contaminated clothing, wash skin thoroughly with water and soap for at least 15 minutes, medical attention if symptoms persist
Eye Contact: Rinse eyes with running water for at least 15 minutes, hold eyelids apart, seek ophthalmological evaluation
Ingestion: Do not induce vomiting, rinse mouth with water, provide fresh air, get immediate medical help
Acute Symptoms: Drowsiness, tremors, convulsions, hypotension, allergic reactions are possible and need urgent care
Suitable Extinguishing Media: Dry powder, CO2, foam, water spray according to surrounding materials
Special Hazards: Combustion produces hazardous fumes including carbon oxides, nitrogen oxides, sulfur oxides, hydrogen chloride, trifluoromethyl compounds
Protective Equipment: Self-contained breathing apparatus, chemical suit, gloves, protective eyewear
Fire Fighting Instructions: Avoid smoke inhalation, use water spray to cool containers, do not release runoff into drains
Explosion Risk: No documented explosion risk but dust-air mixtures from fine powders may pose an ignition hazard in confined spaces
Personal Precautions: Wear chemical protective clothing, respirator or mask, gloves, safety goggles
Spill Clean-Up: Avoid raising dust, use a disposable damp cloth or absorbent material, collect cleanup materials into a suitable waste disposal bag or bin
Environmental Precautions: Prevent entry into drains, waterways, or soil to reduce ecological risk
Decontamination: Wash spill area thoroughly with water and mild detergent after removal of bulk powder
Handling Precautions: Use protective equipment, local exhaust ventilation, handle away from foodstuffs and drink
Hygiene: Wash hands thoroughly after use and before eating or drinking
Storage Conditions: Store in a tightly sealed, labeled container in a cool, dry, well-ventilated place, away from incompatible materials such as strong acids, bases, and oxidizers
Special Storage Measures: Protect from light, moisture, and physical damage, avoid excessive temperature increases
Exposure Limits: Occupational exposure limits not established for this compound but treat as hazardous
Engineering Controls: Use fume hood or local exhaust ventilation during handling
Personal Protective Equipment: Nitrile gloves, lab coat or coveralls, safety glasses or goggles, NIOSH-approved respirator for dust
Environmental Controls: Procedures to avoid environmental contamination, maintain proper waste management
Appearance: White to almost white crystalline powder
Odor: Odorless
pH (1% solution): 4.5 to 6.5
Melting Point: 225-235°C (with decomposition)
Solubility: Soluble in water, slightly soluble in ethanol, insoluble in ether
Boiling Point: Not applicable, decomposes
Vapor Pressure: Negligible
Density: Approximately 1.35 g/cm³
Partition Coefficient (log P): Not available
Chemical Stability: Stable under normal storage conditions
Incompatibilities: Strong acids, bases, oxidizers
Hazardous Decomposition: On combustion or thermal decomposition, releases carbon monoxide, carbon dioxide, nitrogen oxides, sulfur oxides, halogenated compounds
Polymerization: No hazardous polymerization expected under normal conditions
Acute Toxicity: LD50 (oral, rat) estimated at 300-650 mg/kg
Health Effects: Nausea, excessive sedation, dystonic reactions, parkinsonian symptoms, skin and mucous membrane irritation, possible hepatotoxicity with repeated or high-dose exposure
Chronic Effects: Possible risk of neuroleptic malignant syndrome, tardive dyskinesia with prolonged use
Routes of Exposure: Inhalation, ingestion, skin or eye contact
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Mutagenicity, Reproductive Effects: Studies are limited; data on mutagenic or reproductive toxicity are inconclusive or not available
Ecotoxicity: Data limited, suspected to be harmful to aquatic organisms based on chemical class
Persistence and Degradability: Not readily biodegradable, may persist in water or soil
Bioaccumulation Potential: Not established, but structure may indicate some bioaccumulation risk
Mobility in Soil: Expected to be poorly mobile in soil due to solubility and potential for binding to organic matter
Other Adverse Effects: Risk of long-term effects in aquatic environments if large spills occur
Waste Disposal Methods: Dispose of as hazardous pharmaceutical waste through licensed chemical disposal provider
Packaging Disposal: Contaminated packaging should be handled as hazardous waste
Environmental Precautions: Do not dispose of in sinks, drains, or the natural environment
Special Handling: Ensure all waste and containers are properly labeled and sealed before disposal
Regulatory Notifications: Follow all local, regional, national, and international regulations on pharmaceutical waste
UN Number: Not assigned for transport
Transport Hazard Class: Not regulated under ADR, IMDG, IATA but handle with care due to health hazards
Packing Group: Not applicable
Special Precautions for User: Keep container closed, dry, and out of direct sunlight
Transport in Bulk: Not recommended – use clearly marked small containers
Labeling: Label as pharmaceutical material, toxic by ingestion, handle with protective gear
Regulatory Status: Prescription pharmaceutical, controlled distribution in most countries
OSHA (US): Not listed as hazardous under OSHA regulations
TSCA (US): Not listed
REACH (Europe): Not registered as a chemical substance for bulk use; controlled as a medicinal product
WHMIS (Canada): Not classified; medical use only
SARA Title III: Not subject to reporting requirements
Other Regulations: Subject to prescription drug laws, scheduled substance controls, and environmental disposal regulations in many jurisdictions; check local requirements
