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Product Name: Triethyl Phosphite
Chemical Formula: C6H15O3P
Synonyms: Phosphorous acid triethyl ester, Ethanophosphonic acid, Triethyl phosphite, TEPI
CAS Number: 122-52-1
Recommended Use: Used in organic synthesis, as a ligand in catalytic reactions, flame retardant intermediates, plasticizers, stabilizers for plastics, chemical manufacturing
Manufacturer: Consult chemical supplier for latest contact details
Emergency Contact Number: Refer to local or national poison control centers for chemical emergencies
GHS Classification: Flammable liquid (Category 3), Acute toxicity (Oral Category 4), Skin irritation (Category 2), Eye irritation (Category 2), Specific target organ toxicity single exposure (Category 3)
Label Elements: Flame, Exclamation mark pictogram
Signal Word: Warning
Hazard Statements: Flammable liquid and vapor, Harmful if swallowed, Causes skin and eye irritation, May cause respiratory irritation
Precautionary Statements: Keep away from heat, sparks, open flames, and hot surfaces. Avoid breathing fumes, mist, or vapor. Use protective equipment. Wash thoroughly after handling.
Chemical Name: Triethyl Phosphite
Common Name: Triethyl phosphite
CAS Number: 122-52-1
Concentration: ≥99% (commercial grade)
Impurities: Traces of by-products from manufacturing, consult supplier for detailed impurity profile
Additives: No deliberate additives present
Inhalation: Move individual to fresh air, keep at rest in a position comfortable for breathing. Seek medical advice if breathing becomes difficult or irritation persists.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water for several minutes. If irritation or symptoms occur, contact a physician.
Eye Contact: Rinse eyes cautiously with water for several minutes, lifting eyelids. Remove contact lenses if present and continue rinsing. If irritation occurs, seek medical attention.
Ingestion: Rinse mouth, do not induce vomiting unless instructed by poison control or medical personnel. Get immediate medical advice.
Most Important Symptoms: Irritation of skin, eyes, and respiratory tract, nausea if ingested
Immediate Medical Attention: Available for severe irritation, ingestion, or if breathing difficulty develops.
Suitable Extinguishing Media: Foam, carbon dioxide, dry chemical, water spray
Unsuitable Media: Strong water jets can spread burning liquid
Special Hazards: Releases toxic gases including phosphorous oxides, carbon monoxide, and carbon dioxide on combustion
Protective Equipment for Firefighters: Self-contained breathing apparatus (SCBA), chemical protective clothing
Additional Advice: Cool containers with water spray to prevent pressure buildup and explosions. Avoid inhalation of combustion products.
Personal Precautions: Evacuate unprotected personnel from affected area. Use personal protective equipment including gloves, safety goggles, and respirators if necessary.
Environmental Protection: Prevent material from entering sewers, waterways, soil, and confined areas
Spill Cleanup Methods: Absorb with inert material (kaolin, vermiculite, sand). Scoop or shovel into suitable, labeled waste containers for disposal. Ventilate the area extensively.
Decontamination: Clean contaminated surfaces with water and detergent. Dispose of residues according to regulations.
Handling: Operate in well-ventilated areas or chemical fume hoods; minimize vapor formation. Use proper grounding and bonding when transferring liquid. Avoid contact with skin, eyes, and clothing. Do not catch leaking containers by hand.
Storage: Store in tightly closed, clearly labeled containers in a cool, dry, and well-ventilated location. Isolate from incompatible materials like strong oxidizers and strong acids. Keep drums and bottles away from heat, direct sunlight, and open flames.
Incompatibilities: Acids, bases, oxidizing agents, strong reducing agents, moisture
Exposure Limits: No established exposure limits for triethyl phosphite. Practice industrial hygiene measures.
Engineering Controls: Use chemical fume hoods, local exhaust ventilation. Install eyewash stations and safety showers in work areas.
Personal Protective Equipment (PPE): Wear chemical-resistant gloves (nitrile, neoprene), safety goggles, face shield for large quantities, laboratory coat or apron, and appropriate respiratory protection when exposure risk exists.
Hygiene Measures: Do not eat, drink, or smoke near product. Wash hands and face after handling.
Environmental Controls: Prevent release into environment through drains, surface water; contain spills.
Appearance: Colorless to pale yellow liquid
Odor: Mild, distinctive
Odor Threshold: Not determined
pH: Not applicable (non-aqueous)
Melting Point/Freezing Point: -80°C
Initial Boiling Point and Range: 156°C at 1013 hPa
Flash Point: 47°C (closed cup)
Evaporation Rate: Not determined
Flammability: Flammable liquid
Upper/Lower Flammability or Explosive Limits: Not determined
Vapor Pressure: 0.4 hPa at 20°C
Vapor Density: Heavier than air
Relative Density: 0.971 - 0.975 g/cm³ at 20°C
Solubility: Slightly soluble in water, miscible with organic solvents (alcohol, ether)
Partition Coefficient (n-octanol/water): 2.28 (estimated)
Auto-ignition Temperature: 415°C
Decomposition Temperature: Not available
Viscosity: Low viscosity liquid
Chemical Stability: Stable under recommended storage conditions
Possibility of Hazardous Reactions: May react with strong oxidizing agents, acids, or bases producing heat and hazardous compounds
Conditions to Avoid: Heat, flames, sparks, exposure to moisture and incompatibles
Incompatible Materials: Oxidizers, acids, bases, strong reducing agents, moisture
Hazardous Decomposition Products: Phosphorous oxides, ethylene, carbon monoxide, carbon dioxide
Acute Toxicity (oral): LD50 (rat): 1600 mg/kg
Acute Toxicity (dermal): Data not available
Acute Toxicity (inhalation): No data
Skin Corrosion/Irritation: Causes irritation to skin
Eye Damage/Irritation: Causes irritation to eyes
Respiratory Sensitization: May cause respiratory tract irritation
Germ Cell Mutagenicity: Not classified for mutagenicity
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, OSHA
Reproductive Toxicity: No evidence found in available studies
STOT - single exposure: May cause respiratory discomfort
STOT - repeated exposure: Data insufficient
Aspiration Hazard: Not classified
Additional Information: Symptoms of overexposure can include cough, sore throat, headache, nausea
Ecotoxicity: Harmful to aquatic life. LC50 (fish, 96 h): >100 mg/L (estimated value), EC50 (daphnia, 48 h): >100 mg/L
Persistence and Degradability: Expected to undergo slow hydrolysis and biodegradation in environment
Bioaccumulative Potential: Low to moderate based on partition coefficient
Mobility in Soil: Material may volatilize or leach through soil in liquid form
Other Adverse Effects: Prevent run-off to natural water systems
Disposal Methods: Dispose as hazardous organic waste in accordance with local, regional, national, international regulations. Incineration recommended whenever possible. Do not discharge to surface water or sewers.
Contaminated Packaging: Triple rinse containers and send for controlled disposal. Follow local protocols for drum handling.
Special Precautions: Wear suitable protective equipment during waste operations. Label and seal waste containers securely.
UN Number: UN 2323
UN Proper Shipping Name: Triethyl Phosphite
Transport Hazard Class: 3 (Flammable Liquid)
Packing Group: III
Marine Pollutant: Not classified as marine pollutant
Hazard Label: Flammable liquid
Special Precautions: Avoid exposure to heat and flames during transit. Ensure proper labeling and secure packaging.
Regulatory Information: Compliant with ADR/RID, IMDG, ICAO/IATA
OSHA: Regulated as hazardous material under OSHA Hazard Communication Standard
TSCA: Listed on US Toxic Substances Control Act inventory
SARA Title III: Not classified as extremely hazardous, not subject to SARA Section 302. Subject to SARA 311/312 hazard classes: fire, acute health hazard
REACH: Registered substance in the European Union
Other Regulations: Complies with Canadian WHMIS requirements, included in EINECS (EC Inventory), notified under various national chemical control laws
Other Information: Safety datasheet available for workers on request; users should follow training in chemical safety applicable to their country and use case.
