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Product Name: Tilmicosin Phosphate
Synonyms: 20-Deoxo-20-(3,5-dimethylpiperidin-1-yl)desmycosin Phosphate
Chemical Formula: C46H80N2O13 • H3PO4
Recommended Use: Veterinary antibiotic for livestock
Manufacturer: Major pharmaceutical producers for veterinary use
Emergency Contact: Regional Poison Control Center, medical response unit, company’s 24-hour hotline
Hazard Classification: Acute toxicity, oral and inhalation (Category 2); Eye irritation (Category 2A); Respiratory sensitization (Category 1)
Signal Word: Danger
Hazard Statements: May be fatal if inhaled or swallowed, causes eye irritation, may cause allergy or asthma symptoms
Pictogram: Skull and Crossbones, Exclamation Mark, Health Hazard
Precautionary Statements: Avoid generating dust or aerosols, use personal protective gear, wash skin thoroughly after handling, avoid breathing dust, use only outdoors or in a well-ventilated area
Ingredient: Tilmicosin Phosphate
CAS Number: 137330-13-3
Concentration: 95–100%
Impurities: Minor solvent or process-related residues (usually <1%) may be present
Skin Contact: Remove contaminated clothing, rinse skin immediately using plenty of water and soap, seek medical advice
Eye Contact: Rinse cautiously with water for minutes, remove contact lenses if present and easy, continue rinsing, immediate medical consultation recommended
Inhalation: Get victim into fresh air right away, keep at rest in a comfortable position, provide oxygen or artificial respiration if breathing is difficult, seek medical attention
Ingestion: Do not induce vomiting, rinse mouth with water, give water to drink if conscious, seek urgent medical attention
Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide extinguishers
Not Suitable: Direct water jets
Specific Hazards: Emits toxic fumes of carbon oxides, nitrogen oxides, phosphorus oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear
Additional Information: Hazardous decomposition products may form, avoid inhalation of combustion gases
Personal Precautions: Use suitable protective clothing and respirators, keep unnecessary people away from area
Environmental Precautions: Prevent further leakage or spillage if safe, do not allow runoff into drains or natural water courses
Methods for Clean Up: Scoop or sweep spilled material into suitable container, avoid dust formation, ventilate area and wash spill site after material pick-up
Handling: Handle in well-ventilated areas, keep dust formation low, wear appropriate PPE such as gloves, goggles, and respiratory protection, avoid contact with skin, eyes, and clothing, keep away from food, drink, and animal feed
Storage: Store tightly sealed in original containers, keep in a cool, dry, and well-ventilated area away from incompatible substances such as strong oxidizing agents and acids, avoid excessive heat and sunlight, secure from unauthorized access
Engineering Controls: Use local exhaust ventilation or process enclosures to reduce airborne exposure, keep concentrations below recommended occupational exposure limits
Personal Protective Equipment: Respirators suitable for particulate matter, chemical-resistant gloves and lab coat, safety goggles or face shield, suitable protective footwear
General Hygiene: Prohibit eating, drinking, or smoking in work area, wash hands thoroughly after handling, launder contaminated clothing before reuse
Appearance: Off-white to pale yellow crystalline powder
Odor: Slightly characteristic
pH: Slightly acidic (solution)
Melting Point/Range: Approximately 180–190°C (decomposes)
Boiling Point/Range: Not applicable
Solubility: Soluble in water, slightly soluble in ethanol, insoluble in ether
Vapor Pressure: Not applicable at room temperature
Relative Density: About 1.25 g/cm³
Flash Point: Not flammable
Stability: Stable under recommended conditions of storage and use
Incompatible Materials: Strong acids, bases, oxidizing agents
Conditions to Avoid: Moisture, heat, direct sunlight
Hazardous Decomposition: Toxic gases such as carbon monoxide, carbon dioxide, nitrogen oxides, phosphorus oxides on thermal decomposition
Acute Toxicity: Very toxic by inhalation, ingestion, and skin contact, particularly to humans and some animal species
Symptoms: Chest pain, labored breathing, coughing, nausea, headache, possible cardiac effects at high exposures
Chronic Effects: Possible allergic reactions and delayed respiratory sensitization
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: Negative in standard tests
Aquatic Toxicity: Toxic to aquatic life with long lasting effects, may threaten fish and invertebrates
Persistence and Degradability: Slow degradation in water and soil, potential for long-term persistence
Bioaccumulation: Risk of accumulation in aquatic organisms
Other Environmental Data: Contamination of waterways should be prevented, report major releases to local authorities
Waste Disposal Methods: Dispose of as hazardous chemical waste under applicable local, regional, and national regulations; incinerate in specialized facility if possible
Contaminated Packaging: Triple rinse containers before recycling or disposal, treat rinsate as hazardous waste
Precautions: Do not dispose of material in drains, sewers, or the environment, segregate from general waste streams
UN Number: 2811 (Toxic solid, organic, n.o.s.)
Proper Shipping Name: Toxic solid, organic, n.o.s. (contains Tilmicosin Phosphate)
Hazard Class: 6.1 (Toxic substance)
Packing Group: II or III depending on concentration
Label: Toxic (skull and crossbones symbol)
Special Precautions: Protect from physical damage, avoid dust generation, transport in secure, closed containers, inform personnel of risks
Regulatory Status: Listed on major chemical inventories (EPA TSCA, EU REACH, China IECSC)
Labeling Requirements: Comply with OSHA Hazard Communication Standard, European CLP Regulation, and GHS recommendations
Other Regulations: Veterinary use only, subject to restrictions and maximum residue limits, environmental release must comply with regional policies, strict worker safety protocols apply
