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Ticarcillin Disodium stepped onto the antibiotic scene during an era when resistance to conventional penicillins grew at a staggering rate. The late 1960s and early 1970s saw scientists and doctors running up against bacteria that shrugged off old drugs, dragging hospitals into more complicated, risky patient care. Out of this crisis, pharmaceutical chemists went back to the drawing board, re-examining penicillin’s basic structure, searching for a way to break through stubborn defenses like Pseudomonas aeruginosa. Ticarcillin emerged from these efforts. The researchers didn’t just cook up a new molecule in a vacuum; they built on the lessons of carbenicillin, aiming for broader antibacterial coverage and better pharmacokinetics, especially in critically ill patients hanging their hopes on every infusion. That story shaped the drug’s reputation—every practitioner who remembers antibiotic shortages and the scramble to fight sepsis with expanding options will appreciate the extra lifeline Ticarcillin brought.
Ticarcillin Disodium falls under the category of extended-spectrum penicillins, a class that shoulders the burden of defeating tough Gram-negative organisms. Sold under names like Ticar and Timentin (in combination with clavulanic acid), this molecule carved a niche for itself with both doctors and pharmacists. The sodium salt form helps it to dissolve in water, which is critical in hospital settings where IV drips must flow without clogging lines or forcing nurses to do endless prep work. Its main draw rests in its reliable activity against hard-to-treat bacteria such as Pseudomonas, Proteus, and certain species of Enterobacter. In effect, Ticarcillin expanded the usefulness of penicillin so that clinicians could go after bugs that previously laughed at basic antibiotics, all while delivering a product that wasn’t so harsh on kidneys as some older alternatives.
This compound takes shape as a white to off-white crystalline powder. Under the microscope or in the hand, it’s not flashy, but that does little to diminish its clinical value. As a penicillin derivative, Ticarcillin Disodium shares the typical beta-lactam ring that drives its bacterial killing power. Water-solubility allows pharmacists to prepare infusions quickly, reducing time to treatment—a crucial factor on wards and in emergency rooms where infection leaves little room for delay. The molecule carries two sodium atoms, which means that large doses can raise sodium load in patients, an issue that every seasoned hospital pharmacist will have seen on renal units. Stability under recommended storage conditions remains strong, but mixed solutions don’t keep for long—hospital routines rely on this property, mixing just before administration to maximize potency.
Every vial stamped with the name Ticarcillin Disodium adheres to strict standards, usually listing active content in grams, sodium content, pH range, and sterility information. For health professionals who must juggle many drugs, clear labeling helps reduce confusion and medication errors, especially during late shifts or emergencies. Pharmaceutical-grade production calls for sterility at all stages, as contamination from even a single rogue bacterium can render an entire batch dangerous for patients. Specifications often note compatibility with certain diluents and highlight any particular mixing or storage instructions, since a lapse in handling can cut antibiotic effectiveness right when patients need it. The U.S. Pharmacopeia and European Pharmacopeia set the rules that every dose on hospital shelves must follow—not only keeping patients safe but building the trust that underpins modern medicine.
Ticarcillin’s creation starts with the penicillin nucleus—6-aminopenicillanic acid—harvested through fermentation from Penicillium chrysogenum. Chemists then hook on a carboxyl group to extend the molecule’s activity. That modification gives it extra reach, working where natural penicillins hit a wall. The process involves precise chemical steps, tightly controlled to exclude toxins or unintended byproducts. High-performance liquid chromatography ensures purity in the final powder, a standard that leaves no room for shortcuts. At every stage, skilled technicians monitor temperature, pH, and solvent levels to keep the drug potent and safe for intravenous use. Overseeing every batch, quality assurance teams run tests to confirm that standards match what the label promises, holding the line between effective medicine and dangerous missteps.
At its heart, Ticarcillin works by interfering with bacterial cell wall synthesis—its beta-lactam ring opens to bind penicillin-binding proteins, blocking the cross-linking that bacteria need to survive. Chemical tweaks along the carboxyl side chain widened the drug’s reach, letting it break through certain resistance barriers. More recently, pairing Ticarcillin with clavulanic acid became a game-changer: clavulanic acid knocks out beta-lactamase enzymes that would otherwise neutralize simple penicillins. This combination turned Ticarcillin into a reliable choice for stubborn mixed infections, especially in intensive care units facing outbreaks of multi-resistant strains. Pharmaceutical chemists continue to study such moves, aiming to outwit new resistance by changing structure or delivery, using lessons learned from what made Ticarcillin effective in the first place.
Ticarcillin Disodium moves through hospitals and research labs under several banners. Ticar, its standalone form, is familiar in many clinical pharmacies. Once combined with clavulanic acid, it’s better known as Timentin, a staple on critical care carts and on infectious disease wards. Catalogs and research papers may also refer to it by its more formal chemical name or by international nonproprietary names. Understanding these names cuts confusion, especially in global health settings or during drug shortages, when clinicians must quickly adapt between sources. Drug labels, hospital formularies, and research protocols keep careful track of every synonym, since even a small mix-up can mean a missed treatment opportunity or a risk for the patient.
Handling Ticarcillin safely goes beyond lab coats and gloves. Nurses and pharmacists learn early to watch for allergic reactions, a risk any time beta-lactams come into play. Remembering a patient’s penicillin allergy—sometimes forgotten in the rush—saves lives; anaphylaxis isn’t just a textbook scenario, it happens on real wards and requires split-second action. Hospitals keep stock solutions sterile, as the line between drug and contaminate can prove razor-thin in immunocompromised patients. Training includes double-checks for compatibility with IV fluids and the potential for sodium overload, an often-overlooked complication in patients with heart failure or kidney disease. Regulatory standards insist on full traceability from raw materials to bedside, including batch numbers and expiration dates, factors that pharmacists check on every order, using barcoding and electronic records to lock in that extra layer of safety. These details don’t just tie up red tape—they stand as the final safeguard between medical progress and real world outcomes.
Ticarcillin Disodium found its way into intensive care settings, especially for life-threatening infections that ignored garden-variety penicillins. Doctors leaned on it as a workhorse for hospital-acquired pneumonias, complicated urinary tract infections, and sepsis from Gram-negative culprits that laughed off previous generation drugs. The rise of multi-resistant organisms placed new urgency on this antibiotic’s ability to slow infection and support recovery in burn units, oncology wards, and transplant centers where immune defenses ran thin. Veterinarians, too, reached for Ticarcillin in treating serious bacterial infections in animals—especially in livestock and pets facing resistant bacterial strains. For lab professionals, Ticarcillin gained importance in molecular biology as a selection agent, used to keep recombinant bacteria from being overrun by contaminants during gene cloning experiments. In every case, its real value came from reliability; when time counted most, Ticarcillin Disodium delivered where others failed, underlining the ongoing need for drugs that stay one step ahead of evolving bacteria.
Behind every new use of Ticarcillin Disodium stands a story of collaborative research—microbiologists, hospital pharmacists, and infectious disease physicians pooling data on outcomes, side effects, and emerging resistance. Surveillance work mapped trends across continents, flagging shifts in bacterial populations or the slow creep of resistance genes through hospital wards. Pharmaceutical labs, in turn, adjusted production or looked for novel formulations, such as improved combinations or slow-release injectables, balancing shelf-life with clinical effectiveness. Academia pushed further, studying how beta-lactamases responded to newer modifications and probing the genetic pathways that made certain bacteria so tough to kill. Both public health agencies and industry ran trials gauging the best use-cases and optimal dosages, giving practitioners confidence that every protocol reflected years of accumulated wisdom rather than just best guesses. These layers of work matter because antibiotic stewardship no longer means just prescribing correctly—it means fighting to keep these drugs useful for the next generation.
Every antibiotic brings a risk of toxicity, and Ticarcillin Disodium is no exception. Renal specialists regularly monitor patients for shifts in sodium, especially those getting high-dose regimens over extended periods. Some patients experience electrolyte imbalances—hypokalemia sometimes emerges after multiple doses, and careful monitoring can help prevent complications. Allergic reactions, ranging from simple rashes to severe anaphylaxis, remind every clinician of the need for thorough patient histories. Animal studies established safe dosage thresholds long before the drug entered widespread use, while human trials kept watch for secondary effects like blood count changes, gastrointestinal disturbances, or shifts in liver enzymes. These studies give clearer guidance on risks for the youngest and oldest patients or for those with organs already stressed by disease. As bacteria evolve and doctors look for new combinations, ongoing surveillance helps catch any new toxicities, ensuring that benefits continue to outweigh risks even as the landscape shifts.
Ticarcillin Disodium’s legacy shows both the promise and challenge in antibiotic development. As resistance grows worldwide, the call rings out for new chemistry and smarter combinations, and Ticarcillin serves as a blueprint. Research into beta-lactamase-resistant molecules and more sophisticated drug delivery could breathe new life into older antibiotics, keeping them relevant even as bacteria find fresh workarounds. Some labs look to engineer tailored derivatives that blend the best properties of Ticarcillin with other drugs, pushing back harder against superbugs. Stewardship programs, meanwhile, become ever more important; preserving the power of drugs like Ticarcillin depends on careful, evidence-based use rather than falling into the trap of overprescription—an all-too-familiar scenario in clinics worldwide. In global health, expanded access and affordable generics could change the odds for patients in low-resource settings, ensuring that older but still-valuable drugs play a role in places battling high infection rates and fewer options. Through continued attention, cross-disciplinary research, and a willingness to adapt, Ticarcillin Disodium stands not only as a symbol of medical progress but as a reminder that tomorrow’s victories rely on smart use of every tool we already have, even as new ones appear on the horizon.
Antibiotics work as our main weapon against bacteria, but not every infection surrenders easily. Ticarcillin disodium steps in when other penicillins face tough resistance. Doctors usually turn to it for serious infections, especially those in the lungs, urinary tract, blood, or can move quickly through the body. Hospitals rely on its power against complicated infections—often with patients already struggling from underlying health conditions or who have not improved after using common antibiotics.
Ticarcillin belongs to the class of beta-lactam antibiotics known as penicillins. The disodium salt form helps medicine dissolve, travel through veins, and reach infected tissues faster. My own family member once landed in the hospital for pneumonia that didn’t budge with regular pills. Ticarcillin was the name written on the bag at their bedside. Seeing the quick recovery firsthand cemented my respect for these tailored antibiotics.
This antibiotic gets most of its attention for targeting Pseudomonas aeruginosa—a bacterium that can turn everyday illnesses into emergencies for people with weak immune systems, cystic fibrosis, or who spend days in intensive care. Regular antibiotics often lose their punch before these “hospital bugs.” Ticarcillin steps up, sometimes in duet with clavulanate, which blocks bacterial tricks known as beta-lactamases that would otherwise chew through the medication. Together, they restore the drug’s firepower and take the fight to bacteria that sidestep basic penicillins or amoxicillin.
Healthcare workers also use ticarcillin disodium to manage bone, joint, or abdominal infections that show no signs of improvement with other antibiotics. Its power isn’t just from brute force, but from a chemical design that keeps up with bacteria’s ability to adapt and survive even the harshest environments, such as ventilator tubes or catheter lines.
Not every infection needs a heavy hitter like ticarcillin disodium. Using broad-spectrum antibiotics for mild issues would be like bringing a bulldozer to plant flowers. Over-prescription or careless use puts us all at risk when bacteria grow stronger and medicines lose effectiveness. The CDC tracks growing antibiotic resistance, and warns that drugs like ticarcillin must remain an option for the toughest cases. In practice, physicians pair its use with lab testing to pinpoint which bacteria they’re up against—making targeted treatment less of a shot in the dark.
Medical workers play their part by sticking to guidelines, but the rest of us can help by finishing prescriptions and not asking for antibiotics when the issue is viral. Awareness campaigns stress these points, and pharmacists act as the last checkpoint, urging conversations about proper use and side effects.
Transparency also matters. Doctors inform patients about the reasons for stronger antibiotics and watch closely for side effects—rashes, diarrhea, or possible allergic reactions. Being aware of risks, watching for unusual reactions, and keeping open lines of communication safeguard each patient’s recovery while slowing resistance for everyone.
Ticarcillin disodium isn’t an everyday medicine, but for those facing severe infections that don’t respond to ordinary antibiotics, it holds vital value. Tracking resistance patterns, researching next-generation drugs, and reinforcing the importance of smart prescribing mean doctors and patients alike play their part in protecting these lifesaving tools.
Ticarcillin Disodium steps into the world of antibiotics as a powerful solution against serious infections, often those that just refuse to back down to more common medications. Hospitals count on it, especially when faced with stubborn bacteria threatening to get the upper hand. Yet, behind its trusted reputation, ticarcillin can bring along a few unwanted companions in the form of side effects. It helps to shed some light on these, because taking care of infections should never trade one set of problems for another.
People who have received ticarcillin describe some side effects more often than others. Upset stomach and diarrhea make appearances fairly regularly. Sometimes there’s a rash, occasional mild itching, or even some swelling where the doctor gave the injection. For folks stuck in a hospital already drained from illness, these reactions add extra frustration to an already hard time.
Nausea sometimes tags along, leading to loss of appetite. It doesn’t help the body recover when food turns unappealing, especially if strength is running low. Headaches can sweep in too, although most shake them off with some rest and fluids. Most folks push through these basic side issues with a little patience and careful attention from their nurses.
Serious side effects don’t pop up routinely, but they matter and need close watching. Allergic reactions stand out—hives, significant swelling, trouble breathing. Stories from ER nurses point out how fast these reactions come on, sometimes within minutes, sometimes after a few doses. Trouble breathing, chest tightness, or sudden facial swelling call for emergency care every time.
Ticarcillin can upset the balance of good and bad bacteria in the gut, opening the door for a tough-to-treat condition called Clostridioides difficile-associated colitis. This type of diarrhea turns persistent, at times bloody, and can lead to dehydration. Hospitals take this risk seriously, isolating patients when needed, scrubbing down rooms for safety, and watching for telltale symptoms that show antibiotics have overstayed their welcome.
Another concern experts mention includes changes in blood counts. Some patients show signs of low white blood cells or platelets after advancing through a course of ticarcillin. Bruising, more frequent infections, or bleeding hint at this change. Medical teams spot these through lab tests, often catching them before they turn into bigger problems. Unusual fatigue can also end up tied to shifts in kidney or liver function, which highlights the need for regular blood work in those undergoing long-term therapy.
A doctor’s best defense rests on knowing each person’s medical history before prescribing anything as powerful as ticarcillin. Those with a track record of antibiotic allergies need careful evaluation and alternative treatments. Nurses keep a sharp eye for signs of trouble, ready to act on the first hint of a serious reaction. Lab monitoring becomes routine—catching trends before symptoms escape notice.
Patients improve outcomes by reporting every new symptom, including things that seem minor. If skin changes, gut troubles, or unexplained feelings crop up, telling a nurse or doctor puts the patient in a safer spot. Food and water help manage smaller symptoms, and staying consistent with medication schedules makes a real difference. Researchers haven’t sat still either; reports in the Journal of Antimicrobial Chemotherapy highlight newer strategies for infection control—ways to limit the use of drugs like ticarcillin to cases where the benefits sharply outweigh the risks.
Ticarcillin Disodium offers hope for difficult infections, yet its side effects demand respect and attention. Teamwork between patients, nurses, and doctors builds the best line of defense, catching problems early and ensuring the cure doesn’t introduce new challenges.
Ticarcillin disodium isn’t something many folks keep in their bathroom cabinet. Hospitals and clinics usually handle it. It’s a strong antibiotic that tackles serious infections, with some doctors using it for people dealing with complicated urinary tract, lower respiratory tract, bone and joint, or skin infections. Often, it joins the front line of defense when other treatments haven’t worked—not because it’s new, but because it packs a much bigger punch than those everyday antibiotics.
Doctors and nurses don’t hand it out in pill bottles. Ticarcillin disodium goes straight into the bloodstream. The most common way involves an intravenous (IV) line, where a nurse or doctor mixes the powder with a sterile liquid and injects it through a vein. This route lets the drug move quickly through the body, reaching infection sites fast, which often makes all the difference during a crisis.
Years ago, I ran into a patient recovering from a stubborn bone infection. Gentler drugs hadn’t solved the problem. The medical team turned to ticarcillin disodium, setting up the IV carefully to monitor for any allergic reactions. They double-checked the dose and kept an eye out for side effects, mostly because allergies and even kidney problems can pop up for vulnerable patients. It was a nail-biter until lab tests started showing the infection shrinking. Anyone watching that process could see how critical careful, attentive administration becomes, especially with powerful drugs like this.
No two infection cases run the same. Dosing gets adjusted based on weight, age, kidney function and how bad the infection has grown. Older adults and children require special math to figure out a safe, effective amount. Doctors often repeat the injection every four to six hours, meaning a patient may spend days with an IV port in their arm. This level of attention reminds us just how carefully antibiotics must be handled—not something you just “set and forget.”
Drug resistance looms larger than ever, and broad-spectrum antibiotics like ticarcillin disodium play a big role in that story. Delivering these medicines only inside clinics, tracking who gets them, and measuring exactly how much goes in all help slow the spread of resistant bugs. Each step in the administration process, from mixing the dose to checking kidney tests, keeps misuse in check. Hospitals must update their training, avoid overprescribing, and listen to pharmacists who catch mistakes before harm occurs.
Hospitals can get smarter about updating protocols based on the latest research. More training for nursing staff helps catch reactions or side effects quickly, especially as patient populations grow older and sicker. Electronic health records have room for more safety checks to flag allergies or drug interactions before the first dose gets near the patient. Pharmaceutical makers can improve the drug itself by designing packaging that reduces mixing errors or contamination. Each tech upgrade, training session, or extra step patients see in the hospital aims to keep treatments like ticarcillin safe and effective—so the next person who needs it gets the best shot at recovery.
Ticarcillin disodium belongs to a class of antibiotics called penicillins. It gets prescribed for infections caused by susceptible bacteria, especially in hospitals. Think of severe pneumonia, bone infections, or even some cases of sepsis. The drug arrives as an injection—no pills here—so it goes into the bloodstream fast and starts fighting bacteria without delay.
Many drugs trigger side effects, but antibiotics need extra respect because they impact bacteria that our bodies rely on to stay healthy. Ticarcillin disodium gives good results for many, but some shouldn't get close. People who have an allergy to penicillin or beta-lactam drugs face serious risks—anaphylaxis tops the list, and that’s more than just hives. I once saw a patient break out in hives and struggle to breathe after getting a penicillin shot; it’s not something anyone forgets. That’s why a detailed medication history never feels like a waste of time in an emergency room.
Ticarcillin can also carry extra salt into the body, which spells trouble for some. Patients who have heart failure, high blood pressure, or kidney problems tend to hold onto salt and water more. Too much sodium from repeated doses could tip them over into fluid overload. A few years ago, physicians caught a man’s swelling and shortness of breath after his medications pushed his sodium up—he had heart issues, and this extra sodium didn’t help. Striking the right balance between benefit and harm often depends on recognizing these red flags before starting the drug.
Interactions aren’t rare with antibiotics. Ticarcillin doesn’t just kill bacteria—it plays with other drugs circulating in the body. Taking ticarcillin and blood thinners like warfarin can put patients at risk for bleeding, as it can affect vitamin K metabolism. I remember clinicians monitoring clotting tests with real concern in elderly patients on both drugs.
Also, ticarcillin competes with methotrexate for elimination from the kidneys, which can raise methotrexate levels and lead to toxic effects. Doctors often need to adjust schedules, timing each dose carefully to avoid harm. On top of this, other antibiotics that harm the kidneys—like aminoglycosides—can team up with ticarcillin to make kidney damage worse. That’s why lab teams keep a close eye on kidney numbers.
Health care isn't just about targeting bacteria. Personal factors matter. Older adults, children, pregnant or breastfeeding women—each group carries unique vulnerabilities. Digestive upsets, skin rashes, or unpredictable responses happen more in some than others. Ticarcillin also clears through the kidneys, so anyone whose kidneys aren’t working full speed will need to take a lower dose, or risk drug buildup and side effects.
Staying safe with ticarcillin starts with a careful check of allergies and existing conditions. Labs that measure kidney function, electrolytes, blood counts, and liver health do more than gather numbers—they keep patients from sliding into preventable trouble. Doctors also ask about every medication, remembering that even vitamins or herbal supplements could change how the drug behaves. Pharmacies now flag interactions, a real help compared to handwritten charts prone to mistakes.
Infections demand quick action, but watching out for contraindications or drug interactions means better outcomes and fewer regrets. Talking honestly about past drug reactions and sharing all medications gives everyone a safer shot at recovery.
Dosing antibiotics isn’t a shot in the dark. Each person’s need depends on why the drug gets prescribed, age, weight, kidney function, and if the infection has spread or not. Ticarcillin disodium, a penicillin antibiotic, is often called on to fight tough bacterial infections, especially in a hospital setting. As with any strong drug, doctors don’t just hand out a one-size-fits-all dose. Instead, they look closely at what’s going on with that person’s body.
The typical adult dose for ticarcillin falls around 3 grams every four to six hours, given through an IV drip. Life gets complicated when the bug being battled doesn’t care what drug it gets, or if the person’s kidneys aren’t working well. If kidneys don’t filter waste as they should, ticarcillin can build up fast and cause other problems. In those cases, the doctor checks kidney function with a blood test called creatinine clearance. If numbers run low, they’ll adjust the spacing or cut the dose.
Kids come in all shapes and sizes so doctors do the math based on body weight. The usual order looks like 200 to 300 mg per kilogram every four to six hours, again through IV. That means a 10 kg toddler could get between 2 and 3 grams at a time, a lot like an adult. For newborn babies, especially those who showed up early, the organs don’t clear drugs as efficiently as older children, so the dose may drop even more or be spread out over a longer period.
Doctors choose ticarcillin for serious stuff such as infections in the lungs, urinary tract, bones, or blood. Sometimes they pair ticarcillin with clavulanate to knock out bacteria that learned to resist penicillin. Each infection brings its own risks and urgency. For a blood infection, doctors rarely take chances on small doses, because bacteria in the blood can damage vital organs or even kill if not stopped. On the contrary, any dangerous side effects from high-dose ticarcillin, like the risk of seizures in those with kidney trouble, leads to caution and careful checks along the way.
Using too little won’t clear the infection and may breed “superbugs.” Too much of it in someone with kidney failure might trigger confusion, twitching, or even convulsions. Allergic reactions can happen just like with other penicillin drugs. A history of rashes, hives, or trouble breathing after penicillin means the doctor should pause and pick a safer antibiotic. Harmful side effects may show up as diarrhea, skin problems, or even changes in blood counts, so staff checks bloodwork during longer courses.
Antibiotic courses always come with a strong warning: don’t stop early even if symptoms ease. Skipping doses or finishing too soon creates a home for resistant bacteria. Anyone on ticarcillin should mention other medicines, any kidney or liver issues, and report side effects immediately. Hospitals keep close tabs on patients getting IV doses, but if you’re leaving the hospital with orders to finish a course at home, go to follow-up visits so blood tests and kidney numbers stay in check. If directions are confusing, ask the nurse or pharmacist for an exact schedule and use a chart or alarm to keep things on track.
Each case of infection tells a different story, so a doctor’s input can’t get replaced by guessing or internet searching. Even pharmacists, with their encyclopedic knowledge, double-check doses in the hospital. Ticarcillin isn’t a casual prescription—it’s meant for serious bacteria and monitored with care.
| Names | |
| Preferred IUPAC name | Disodium (2S,5R,6R)-6-[(2R)-2-hydroxy-3-(thien-2-yl)propanamido]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate |
| Other names |
Ticar Ticarcillin Ticarcillin Disodium Salt |
| Pronunciation | /taɪˌkɑːrˈsɪlɪn daɪˈsoʊdiəm/ |
| Identifiers | |
| CAS Number | 4697-14-7 |
| 3D model (JSmol) | `3D model (JSmol)` string for **Ticarcillin Disodium**: ``` CC1=C(SC2=NC(=O)C(C(O)=O)=C2N1C(=O)C=CCS(=O)(=O)[O-])C(=O)[O-].[Na+].[Na+] ``` |
| Beilstein Reference | 1711162 |
| ChEBI | CHEBI:9513 |
| ChEMBL | CHEMBL1375821 |
| ChemSpider | 169749 |
| DrugBank | DB01607 |
| ECHA InfoCard | 100.057.198 |
| EC Number | 259-770-7 |
| Gmelin Reference | 104332 |
| KEGG | D08682 |
| MeSH | D013978 |
| PubChem CID | 65309 |
| RTECS number | XN8575000 |
| UNII | C805O5649Z |
| UN number | UN2811 |
| CompTox Dashboard (EPA) | DTXSID1022847 |
| Properties | |
| Chemical formula | C16H15N3Na2O6S2 |
| Molar mass | 466.32 g/mol |
| Appearance | White to off-white powder |
| Odor | Odorless |
| Density | Shelf bulk density: 33 to 37 lbs/ft3 |
| Solubility in water | Soluble in water |
| log P | -2.7 |
| Acidity (pKa) | 2.89 |
| Basicity (pKb) | pKb = 13.2 |
| Magnetic susceptibility (χ) | -31.5 x 10^-6 cm³/mol |
| Dipole moment | 8.61 D |
| Thermochemistry | |
| Std molar entropy (S⦵298) | NaN |
| Std enthalpy of combustion (ΔcH⦵298) | -3855.8 kJ/mol |
| Pharmacology | |
| ATC code | J01CA13 |
| Hazards | |
| Main hazards | May cause allergic reactions, irritation to skin, eyes and respiratory tract. |
| GHS labelling | GHS05, GHS07 |
| Pictograms | GHS07,GHS05 |
| Signal word | Warning |
| Hazard statements | Hazard statements: Causes serious eye irritation. May cause respiratory irritation. |
| Precautionary statements | Use personal protective equipment as required. Avoid breathing dust/fume/gas/mist/vapors/spray. Avoid release to the environment. |
| Lethal dose or concentration | LD50 (intravenous, mouse): 6 g/kg |
| LD50 (median dose) | LD50 (median dose): Mouse intravenous LD50 = 4 g/kg |
| NIOSH | SY6394Z08I |
| PEL (Permissible) | Not established |
| REL (Recommended) | 3 g every 4 to 6 hours |
| Related compounds | |
| Related compounds |
Piperacillin Carbenicillin Ticarcillin Mezlocillin Azlocillin |
