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Product Name: Thiamine Nitrate
Chemical Formula: C12H17N5O4S·NO3
Synonyms: Vitamin B1 Nitrate, Thiamin Mononitrate
CAS Number: 532-43-4
Recommended Use: Nutritional supplement, pharmaceutical manufacturing, animal feed additive, laboratory reagent
Supplier: Refer to label or purchase documentation for manufacturer or distributor details
Emergency Contact: Refer to local guidelines for poison control or chemical emergency number
Classification: Not classified as a hazardous substance or dangerous good under GHS; exposure may cause mild irritation
Route of Exposure: Inhalation, skin contact, eye contact, ingestion
Hazard Statements: May cause mild respiratory tract irritation, mild skin or eye irritation on direct contact, upset stomach if ingested in large quantities
Precautionary Statements: Avoid breathing dust, prevent contact with eyes, skin, and clothing, wash hands and exposed areas after handling
Pictograms: No GHS pictogram required; good chemical hygiene recommended
Chemical Name: Thiamine Nitrate
Concentration: 100% (pure form; may vary with dilution or formulations)
Impurities: None expected in technical or pharmaceutical grades
Molecular Weight: 379.37 g/mol
EC Number: 208-568-1
Inhalation: Move person to fresh air, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with water, seek medical help if irritation occurs
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, consult physician if irritation develops
Ingestion: Rinse mouth, drink water to dilute, seek immediate medical advice if feeling unwell
Advice to Physician: Treat symptomatically; no specific antidote known, supportive care only
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Do not use a direct jet of water on substance fires as it may spread the material
Fire Hazards: Thiamine Nitrate can decompose on heating to release toxic fumes like nitrogen oxides, sulfur oxides, carbon oxides
Protective Equipment: Firefighters should wear self-contained breathing apparatus, full protective gear
Special Procedures: Use water spray to keep fire-exposed containers cool and to disperse vapors, prevent runoff from entering water sources
Personal Precautions: Avoid inhalation of dust, contact with skin or eyes; wear suitable protective clothing including gloves and eye/face protection
Environmental Precautions: Prevent spills from entering drains, waterways, or soil
Methods for Clean-Up: Sweep up and place in suitable containers for disposal, avoid generating dust, ventilate area, thoroughly wash spill area with plenty of water
Decontamination: Clean contaminated surfaces with detergent and water, observe waste disposal protocols
Handling: Operate in a well-ventilated area, avoid dust formation, do not eat, drink, or smoke near product, avoid contact with eyes, skin, clothing
Hygienic Practices: Wash hands after handling, change contaminated clothing, use clean protective gear daily
Storage Conditions: Store in tightly closed original container, keep away from moisture, excessive heat and incompatible substances
Incompatible Materials: Strong oxidizing agents, reducing agents, strong acids and bases, moisture
Storage Temperature: Room temperature (15–25°C), avoid freezing or overheating
Engineering Controls: Use local exhaust ventilation to keep airborne levels low
Personal Protection: Wear chemical-resistant gloves (nitrile, latex), safety goggles or face shield, appropriate respiratory protection if dust clouds develop
Occupational Exposure Limits: No established limit, minimize dust creation
General Protection: Protective work clothing, washing facilities, eye wash stations recommended where product is handled
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: Slightly acid to neutral (in 1% aqueous solution)
Melting Point: Decomposes before melting (approx. 140-145°C)
Boiling Point: Not applicable
Solubility: Soluble in water
Vapor Pressure: Not applicable
Specific Gravity: Approx. 1.5 g/cm³
Partition Coefficient: log Kow -2.09
Flash Point: Not flammable
Autoignition Temperature: No data available
Decomposition Temperature: Decomposes >140°C
Evaporation Rate: No data available
Chemical Stability: Stable under normal storage and handling conditions
Reactivity: Inert under most conditions; avoid contact with incompatible substances
Conditions to Avoid: Moisture, excessive heat, sources of ignition, light
Materials to Avoid: Strong oxidizers, reducing agents, acids, bases
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon dioxide, carbon monoxide
Polymerization: Will not occur
Acute Toxicity: Oral LD50 (rat) > 5000 mg/kg, low toxicity
Irritation: May cause mild irritation to skin, eyes, respiratory tract on direct contact
Sensitization: No evidence of skin sensitization
Chronic Effects: High repetitive exposures may cause vitamin B1 oversupply symptoms, not expected under normal handling
Carcinogenicity: Not listed by IARC, NTP, OSHA as a carcinogen
Mutagenicity: No data indicating mutagenicity in standard tests
Reproductive Effects: No adverse effects expected at occupational exposure levels
Ecotoxicity: Practically nontoxic to aquatic organisms; LC50 for fish and daphnia >100 mg/L
Degradability: Readily biodegradable in the environment
Bioaccumulation: Low potential for bioaccumulation
Mobility in Soil: High water solubility suggests some mobility
Aquatic Impact: Large spills may cause oxygen depletion due to microbial breakdown, avoid uncontrolled release to waterways
Disposal Methods: Dispose of in accordance with national and local regulations
Unused Material: Can be disposed of as nonhazardous waste, typically in landfill or by incineration
Contaminated Packaging: Empty containers should be triple rinsed, punctured or crushed, and sent to approved waste treatment facilities
Precautions: Do not allow product or waste to reach watercourses, sewers, or soil, follow waste code standards relevant for chemicals
UN Number: Not regulated for transport
UN Proper Shipping Name: Not hazardous
Transport Hazard Class(es): Not classified
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions: Protect from moisture, use sealed, labeled containers, ensure compliance with local transportation laws
OECD Status: Thiamine Nitrate falls under non-hazardous provisions according to most international chemical inventories
TSCA (USA): Listed
EINECS (Europe): Listed
DSL/NDSL (Canada): Listed
REACH: Exempt as a food/health substance; check individual country requirements
Labeling Requirements: Generally no hazard label required in the workplace for pure vitamin B1 nitrate
Workplace Controls: Protected under general chemical hygiene regulations, not specifically regulated due to low hazard profile
