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Product Name: Tetramethylsilane
Chemical Formula: Si(CH₃)₄
CAS Number: 75-76-3
Synonyms: TMS, Silicon tetramethyl
Recommended Use: NMR internal standard, chemical synthesis
Supplier: Chemical manufacturers, specialized laboratory supply companies
Emergency Contact: Local emergency services, poison control centers
GHS Classification: Flammable liquid (Category 2)
Signal Word: Danger
Hazard Statements: Highly flammable liquid and vapor. Causes skin and eye irritation. May cause respiratory irritation. Harmful if inhaled, swallowed or through skin contact.
Pictograms: Flame, exclamation mark
Precautionary Statements: Keep away from heat, sparks, open flames, hot surfaces. Wear protective gloves, protective clothing, eye protection. Avoid breathing vapors, spray, or mist. Use only outdoors or in well-ventilated area. Store in a tightly closed container.
Chemical Name: Tetramethylsilane
Concentration: 99% or higher
CAS Number: 75-76-3
Impurities: Trace hydrocarbon solvents, water
Other Components: No hazardous components above regulatory thresholds
Inhalation: Move affected person to fresh air. If breathing difficult or irregular, seek immediate medical attention. Keep person warm and at rest.
Skin Contact: Remove contaminated clothing. Rinse skin thoroughly with water for at least 15 minutes. Seek medical advice if symptoms persist or develop.
Eye Contact: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing. If irritation continues, seek medical care.
Ingestion: Rinse mouth with water. Do not induce vomiting unless directed by medical personnel. Get medical attention at once.
Symptoms: Dizziness, headache, drowsiness, skin redness, eye irritation, respiratory discomfort
Suitable Extinguishing Media: Dry chemical, carbon dioxide, alcohol-resistant foam. Do not use water directly on fire as product may float and reignite.
Hazardous Combustion Products: Produces toxic gases such as carbon monoxide, carbon dioxide, silicon oxides, formaldehyde during fire.
Special Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective gear. Approach from upwind. Keep containers cooled with water spray to prevent rupture.
Advice for Firefighters: Evacuate area, fight fire from a safe distance. Prevent runoff from firefighting from entering drains or waterways.
Personal Precautions: Evacuate unprotected personnel, ventilate area. Eliminate ignition sources. Avoid contact with skin, eyes, and clothing.
Protective Equipment: Wear gloves, goggles, flame-resistant clothing, and respirator suited to the vapors.
Environmental Precautions: Prevent entry into drains, soil, or waterways. Report releases to authorities following local regulations.
Spill Cleanup Methods: Stop leak if safe. Contain spill using inert absorbent materials (sand, earth, vermiculite). Collect in properly labeled containers for disposal. Ventilate after cleanup and destroy contaminated clothing safely.
Handling: Use outdoors or in well-ventilated areas. Avoid breathing vapors, mist, or spray. Do not eat, drink, or smoke during use. Keep away from open flames, heat, hot surfaces or sparks. Ground and bond all transfer and storage equipment. Use spark-proof tools and explosion-proof equipment.
Storage: Keep container tightly closed in a cool, well-ventilated place. Store away from oxidizing agents, acids, ignition sources. Protect from sunlight and moisture. Separate from foodstuffs. Label storage area clearly as flammable.
Exposure Limits: No established OSHA PEL or ACGIH TLV for tetramethylsilane. Use engineering controls to keep exposure as low as possible.
Engineering Controls: Use chemical fume hood or adequate local exhaust. Install explosion-proof ventilation for handling large volumes.
Personal Protective Equipment: Chemical-resistant gloves (nitrile or butyl rubber), tightly fitting safety goggles, flame retardant lab coat, long pants. Use appropriate respirator if engineering controls cannot maintain vapor levels below recommended limits.
Hygiene Measures: Wash hands and face thoroughly after handling. Remove and wash contaminated clothing before use.
Appearance: Clear, colorless liquid
Odor: Ether-like
Odor threshold: Not established
pH: Not applicable
Melting Point / Freezing Point: -97°C
Boiling Point: 27°C
Flash Point: -6°C (closed cup)
Evaporation Rate: Rapid
Flammability: Extremely flammable liquid and vapor
Vapor Pressure: 357 mm Hg at 20°C
Vapor Density: 3.0 (air = 1)
Relative Density: 0.648 (water = 1)
Solubility: Practically insoluble in water, soluble in organic solvents
Partition Coefficient (n-octanol/water): 2.8
Auto-ignition Temperature: 225°C
Decomposition Temperature: Not available
Viscosity: 0.38 mPa.s at 25°C
Chemical Stability: Stable under recommended storage conditions.
Reactivity: Reacts exothermically with oxidizing agents and acids. Can form flammable mixtures with air even at room temperature.
Conditions to Avoid: Heat, flames, sparks, static discharge, exposure to strong oxidizers and acids.
Hazardous Decomposition Products: Silicon oxides, carbon oxides, formaldehyde, methane.
Polymerization: No hazardous polymerization expected under normal conditions.
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Inhalation may cause headache, dizziness, drowsiness, central nervous system depression. Skin contact produces irritation, defatting, redness. Eye contact may cause burning or watering. Ingestion can lead to nausea, abdominal pain, central nervous system effects.
Chronic Effects: No data for long-term effects in humans. Animal studies suggest possible liver and kidney effects with repeated high exposures.
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA.
Mutagenicity: No data indicating mutagenicity.
Reproductive Toxicity: No studies available.
Other Information: Effects intensified by solvents or alcohol use. Potential for aspiration hazard if swallowed.
Ecotoxicity: No specific fish, daphnia, or algae toxicity data available; based on volatility and low solubility, risk to aquatic systems increases if released in large amounts.
Persistence and Degradability: Degrades through hydrolysis and photodegradation; limited persistence in water due to high volatility.
Bioaccumulation Potential: Partition coefficient suggests some potential for accumulation but environmental breakdown is rapid.
Mobility in Soil: Likely to evaporate quickly from soil or water.
Other Harmful Effects: Large spills may affect air quality. Avoid release to environment.
Recommended Disposal: Hand over to licensed chemical disposal company. Incinerate in approved facility with scrubber for silicon-containing compounds.
Do Not: Pour into drains, sewers, waterways, or general waste. Never burn in open air.
Contaminated Packaging: Empty containers carry product residue and vapor. Rinse with compatible solvent before scrap disposal as hazardous waste.
UN Number: 3295
UN Proper Shipping Name: Hydrocarbons, liquid, n.o.s. (Tetramethylsilane)
Transport Hazard Class: 3 (Flammable liquid)
Packing Group: II
Labels: Flammable liquid
Special Provisions: Keep away from sources of ignition during transport. Secure containers to prevent leakage or overturning. Separate from strong oxidizers. Emergency response guide provided by carrier.
OSHA Status: Hazardous chemical according to OSHA Hazard Communication Standard
TSCA Inventory: Listed
SARA 311/312 Hazard Categories: Immediate (acute) health risk, fire hazard
SARA Title III Section 313: Not subject to reporting
California Proposition 65: Not listed
Canadian WHMIS: B2 – Flammable liquid, D2B – Toxic material causing other effects
EU Classification: F; R11 Highly flammable
Other Regional Regulation: Check local, regional, and national regulations for obligations beyond federal requirements
