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Product Name: Tetrahydrofurfurylamine
Chemical Formula: C5H11NO
Synonyms: 2-(Aminomethyl)tetrahydrofuran
CAS Number: 2682-49-7
Recommended Use: Intermediate in chemical synthesis, solvents, and specialty chemical applications
Manufacturer Contact: Provided by supplier, includes address, phone, emergency contact
Classification: Causes skin and eye irritation, may harm aquatic life
GHS Label: Exclamation mark symbol for irritant
Hazard Statements: Causes serious eye and skin irritation, harmful if swallowed, may cause respiratory symptoms
Precautionary Statements: Wear gloves, eye protection, avoid breathing vapors and direct contact
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Symptoms: Redness, itching or pain on contact, possible coughing or wheezing following inhalation
Substance: Tetrahydrofurfurylamine
CAS Number: 2682-49-7
Concentration: 95-100%
Impurities: Small quantities of related amines or solvents as detected by quality control,
identification required on batch paperwork
Inhalation: Move affected person to fresh air, keep at rest, seek medical advice if symptoms persist
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing,
seek medical attention if irritation develops
Skin Contact: Remove contaminated clothing, wash skin thoroughly using soap and water,
obtain medical assistance for persistent irritation
Ingestion: Rinse mouth, avoid inducing vomiting unless directed by a medical professional,
seek immediate medical attention
Most Important Symptoms: Burning sensation on skin or eyes, nausea after ingestion, coughing post-inhalation
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Strong water jet may spread chemical
Specific Hazards: Vapors can form explosive mixtures with air, fire releases toxic nitrogen oxides and carbon monoxide
Protective Equipment: Self-contained breathing apparatus and full protective gear
Firefighting Procedures: Prevent runoff from entering water supplies, use water spray to cool containers exposed to fire
Personal Precautions: Wear chemical-resistant gloves, eye protection, avoid inhaling vapors
Environmental Precautions: Prevent product from reaching drains or waterways, use dikes to contain large spills
Methods for Cleanup: Soak up with inert absorbent materials, shovel into suitable containers for disposal, ventilate affected area,
wash spill site after material removal,
notify responsible authorities if significant environmental release occurs
Handling: Work in well-ventilated areas, minimize exposure through use of gloves and goggles, avoid formation of vapor clouds,
maintain good personal hygiene practices
Storage Conditions: Store in cool, dry, and well-ventilated spaces, keep container tightly closed, store away from strong acids,
oxidizers, and sources of ignition
Incompatible Materials: Strong acids, strong oxidizing agents, materials sensitive to amines or organic bases
Exposure Limits: No established occupational exposure limits, monitor workplace air for vapor levels
Engineering Controls: Local exhaust ventilation, fume hoods in laboratories, closed systems, or process enclosures
Personal Protective Equipment: Chemical-resistant gloves (nitrile), safety goggles or face shield, laboratory coats or aprons,
adequate respiratory protection in poorly ventilated areas
Hygiene Measures: Wash hands before eating, drinking, or smoking, remove contaminated clothing and wash before reuse,
do not eat or drink near chemical work area
Appearance: Colorless to pale yellow liquid
Odor: Amine-like with possible slightly musty undertones
Boiling Point: 174°C (345°F)
Melting Point: -40°C (-40°F)
Flash Point: 65°C (149°F)
Vapor Pressure: 0.2 mmHg at 20°C
Solubility: Completely miscible in water
Density: Approximately 0.98 g/cm³ (20°C)
Viscosity: Low
pH: Strongly alkaline (aqueous solution)
Partition Coefficient: Log Kow: -0.55 (estimated)
Chemical Stability: Stable under recommenced handling and storage conditions
Hazardous Reactions: May react with acids, acid chlorides, and oxidizing agents
Conditions to Avoid: Contact with strong oxidizers, exposure to extreme temperatures, open flames
Decomposition Products: Under fire conditions, produces nitrogen oxides, carbon monoxide, carbon dioxide,
possible small molecules of organic origin
Acute Toxicity: LD50 Oral (rat): 910 mg/kg
Inhalation: Vapors cause respiratory irritation, headaches, or dizziness at higher concentrations
Skin Contact: Irritating to skin, repeated exposure may cause dermatitis
Eye Contact: Causes serious eye irritation, pain, redness, possible corneal injury with severe exposure
Chronic Effects: Prolonged or repeated exposure may damage liver, kidneys, or central nervous system
Carcinogenicity: No data suggesting carcinogenic effects in humans
Mutagenicity: No known mutagenic effects in tested systems
Sensitization: Not a known skin sensitizer, though all amines can cause allergic reactions in sensitive individuals
Aquatic Toxicity: Harmful to aquatic organisms, may cause long-term adverse effects in aquatic environment
Persistence and Degradability: Expected to be biodegradable, breaks down in sewer treatment plants under aerobic conditions
Bioaccumulative Potential: Low, due to high water solubility and rapid microbial degradation
Mobility in Soil: High mobility, risk of leaching to groundwater if released
Other Adverse Effects: Product can alter water pH, affecting aquatic life
Waste Treatment Methods: Dispose through licensed chemical disposal contractor, incinerate under controlled conditions
if approved
Contaminated Packaging: Empty containers fully, rinse with water, send to approved drum reconditioner or recycler,
label as hazardous chemical waste
Disposal Precautions: Follow local, regional, and national regulations for disposal
UN Number: Not regulated under many transport regulations, consult specific country rules
UN Proper Shipping Name: Tetrahydrofurfurylamine
Transport Hazard Class: Not classified as dangerous for most forms of transport
Packing Group: III (if transport code applies)
Environmental Hazards: Not classified as marine pollutant, though large spills present a risk
Special Precautions: Avoid heat, store upright, secure containers against movement
TSCA Status: Listed on the US Toxic Substances Control Act Inventory
REACH Registration: Registered in the EU with assigned number
Safety, Health, and Environmental Regulations: Subject to standard workplace hazard communication,
requires labeling using GHS system
SARA 313: Not listed
Canadian DSL/NDSL: Listed
Workplace Classification: Requires chemical risk assessment and employee training,
subject to local reporting rules
Labeling Requirements: Signal word “Warning”, hazard pictograms, safety phrases,
and full supplier identification
