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Product Name: Chlortetracycline Hydrochloride
CAS Number: 64-72-2
Synonyms: Aureomycin hydrochloride, 7-Chloro-tetracycline hydrochloride
Recommended Use: Veterinary antibiotic, research chemical
Manufacturer: [Manufacturer details]
Contact Information: [Contact number, emergency hotline, email address]
Hazard Classification: Eye irritation (Category 2), Skin irritation (Category 2), Sensitizing (Category 1), Specific target organ toxicity (Category 3), Hazardous to aquatic environment (Category 3)
Label Elements: Signal word: Warning; Hazard statements: May cause eye, skin, and respiratory irritation; may cause allergic skin reaction; toxic to aquatic life
Pictograms: Exclamation mark, Health hazard, Environmental hazard
Precautionary Statements: Avoid breathing dust, wear protective gloves/protective clothing/eye protection, use only in well-ventilated areas, wash hands thoroughly after handling
Chemical Name: Chlortetracycline Hydrochloride
Common Name: Aureomycin hydrochloride
Formula: C22H23ClN2O8 · HCl
Concentration: ≥98% purity
Impurities: May contain trace related tetracycline compounds
Eye Contact: Immediately flush with plenty of water for at least 15 minutes; remove contact lenses if present and easy to do; seek medical help
Skin Contact: Remove contaminated clothes; rinse affected area with soap and water for several minutes; seek medical advice if irritation develops
Inhalation: Move to fresh air; keep person at rest, seek medical attention if symptoms like coughing or shortness of breath develop
Ingestion: Rinse mouth with water; do not induce vomiting; get medical assistance if feeling unwell
Note for Physicians: Symptomatic treatment and supportive therapy; show this data sheet to attending medical personnel
Suitable Extinguishing Media: Water spray, foam, dry powder, carbon dioxide
Unsuitable Extinguishing Media: High-pressure water jet
Special Hazards: Thermal decomposition can release carbon monoxide and carbon dioxide, hydrochloric acid fumes, nitrogen oxides, chlorine compounds
Advice for Firefighters: Wear self-contained breathing apparatus, use protective fire-fighting clothing, avoid inhalation of smoke or combustion gases
Additional Measures: Prevent fire-fighting water from entering drains or watercourses
Personal Precautions: Avoid inhalation and direct contact; wear appropriate personal protective equipment such as gloves, lab coat, safety glasses, and suitable respirator
Environmental Precautions: Contain leak or spill; do not let the material enter drains, surface water, or soil
Methods for Cleaning Up: Sweep up and place in suitable containers for disposal; avoid dust generation; ventilate area
Reference to Other Sections: Refer to sections on exposure control, personal protection, and disposal
Handling: Operate in well-ventilated locations; avoid formation and inhalation of dust; use tools and procedures that minimize direct exposure; practice good hygiene to reduce risk of skin and eye contact, especially before eating or drinking
Storage: Store in tightly closed containers; keep in a cool, dry, and well-ventilated area away from direct sunlight, incompatible substances, and food or feed
Incompatible Materials: Alkali metals, strong oxidizers, strong acids
Special Requirements: Make sure container labels remain intact and legible
Occupational Exposure Limits: No specific workplace exposure limit established for this substance
Engineering Controls: Use afume hood or local exhaust; avoid raising dust; keep workplace well-ventilated
Personal Protective Equipment: Safety goggles for eye protection; nitrile gloves for handling; laboratory coat or coveralls to protect skin; dust mask or respirator (e.g., NIOSH N95) if dust forms
Hygiene Measures: Wash hands thoroughly after use; remove contaminated clothing and wash before reuse; do not eat or drink in the working area
Appearance: Yellow to light brown crystalline powder
Odor: Odorless or faint medicinal odor
pH: 2.0 – 4.0 (1% aqueous solution)
Melting Point/Range: Decomposes above 220°C
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water, slightly soluble in ethanol, insoluble in ether
Vapor Pressure: Not available
Relative Density: Approximately 1.75 g/cm³
Partition Coefficient (n-octanol/water): Not determined
Other Properties: Stable under recommended storage conditions; sensitive to heat and light
Chemical Stability: Stable in original packaging at room temperature kept from moisture and strong light
Hazardous Reactions: May react with strong oxidizing agents or strong acids; decomposition can release toxic fumes
Conditions to Avoid: Excessive heat, moisture, exposure to strong sunlight
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides, hydrochloric acid, chlorine compounds
Acute Toxicity: Oral LD50 in rats >8000 mg/kg
Skin Corrosion/Irritation: Can produce skin irritation on exposure
Eye Damage/Irritation: May cause moderate to severe irritation to eyes
Respiratory or Skin Sensitization: May cause allergic skin reactions on repeated or prolonged exposure
Mutagenicity/Carcinogenicity: Limited evidence; not classified as carcinogen by OSHA, IARC, or NTP
Reproductive Effects: Some animal studies suggest effects on fetal development, but data in humans lacking
Target Organs: Gastrointestinal tract, skin, eyes, respiratory system
Aquatic Toxicity: Harmful to fish and aquatic invertebrates; LC50 (fish, 96 h): approx 10–100 mg/L
Mobility in Soil: Moderate persistence; can leach in some soil types
Bioaccumulation: Potential is low, but bioaccumulation in aquatic organisms not fully studied
Other Adverse Effects: Disrupts microbial activity if released in quantity; avoid release into environment and water systems
Waste Treatment Methods: Dispose through licensed chemical disposal contractor; incineration is preferable method following local, regional, and national guidelines
Contaminated Packaging: Rinse with suitable solvent and dispose as hazardous waste
Environmental Precautions: Prevent entry into sewers, drains, or natural water sources; avoid landfill disposal where possible
UN Number: Not classified as dangerous good for transport
UN Proper Shipping Name: Not regulated
Transport Hazard Class: None assigned
Packing Group: Not assigned
Environmental Hazards: Transport in compliance with relevant regulations to avoid spills
Special Precautions: Avoid generating dust during loading/unloading; protect packaging from puncture or rupture
GHS Label: Covered by Hazard Communication Standard; warning symbol required
OSHA: Not specifically regulated, but all occupational safety protocols apply
TSCA Status: Listed
EINECS/ELINCS: Listed
Other Regulations: Observe all applicable federal, state, and local requirements for handling, use, and disposal
Worker Protection: Guidance and control measures provided at the site level; regular safety reviews recommended
