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Product Name: Tert-Butyl Bromoacetate
Chemical Formula: C6H11BrO2
CAS Number: 5292-43-3
Use: Organic synthesis, pharmaceuticals, chemical research
Supplier: [Supplier info redacted for privacy]
Emergency Contact: Refer to local regulations or chemical manufacturer’s emergency response number
Classification: Acute toxicity (oral, dermal, inhalation) – Category 3; Skin corrosion/irritation – Category 2; Eye irritation – Category 2A
Label Elements: Skull and crossbones symbol, exclamation mark
Signal Word: Danger
Hazard Statements: Toxic if swallowed, in contact with skin or if inhaled. Causes skin irritation. Causes serious eye irritation.
Precautionary Statements: Avoid breathing dust or vapors. Wear protective gloves, protective clothing, eye protection, and face protection. Do not eat, drink, or smoke when using this product. Wash thoroughly after handling.
Chemical Name: Tert-Butyl Bromoacetate
Synonyms: tert-Butyl 2-bromoacetate, TBBA
CAS Number: 5292-43-3
Concentration: >98% (pure substance)
Inhalation: Move person to fresh air, keep comfortable and warm, seek medical advice if symptoms persist. If not breathing, give artificial respiration.
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, get medical attention.
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, get medical attention immediately.
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical personnel, seek immediate medical attention.
Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, or water spray
Specific Hazards: May emit toxic fumes of hydrogen bromide and carbon oxides under fire conditions
Protective Equipment: Firefighters should wear full protective clothing and self-contained breathing apparatus
Fire/Explosion Hazards: Avoid breathing combustion gases; containers may explode if heated.
Personal Precautions: Evacuate personnel to safe areas, provide adequate ventilation, use personal protective equipment, avoid inhalation and skin contact
Environmental Precautions: Prevent further leakage or spillage; do not allow chemical to enter drains or waterways
Cleanup Methods: Absorb with inert material like sand or vermiculite, scoop up and dispose of according to local, state, and federal regulations, ventilate area well, clean contaminated surfaces thoroughly.
Handling: Work in well-ventilated spaces, wear suitable protective gear including gloves and safety goggles, avoid contact with skin, eyes, and clothing, prevent inhalation of vapors or mists. Wash hands before eating, after handling.
Storage: Store in tightly closed, properly labeled containers. Keep away from heat, sparks, open flame, and incompatible substances like strong bases, acids, and oxidizers. Store in a cool, dry, well-ventilated space dedicated to hazardous chemicals.
Engineering Controls: Use chemical fume hood, proper ventilation at all times
Personal Protection: Wear chemical splash goggles, gloves (nitrile or neoprene), lab coat or apron, and, for operations above normal laboratory handling, use respirators certified for organic vapors. Facilities should have eyewash stations and emergency safety showers.
Exposure Limits: No established exposure limits from OSHA, ACGIH, or NIOSH, but minimize exposure to lowest possible levels.
Appearance: Colorless to pale yellow liquid
Odor: Not characterized, slightly pungent possible
Melting Point: -23 °C
Boiling Point: 61-63 °C at 12 mmHg
Solubility: Insoluble in water, miscible with many organic solvents
Density: Approximately 1.28 g/cm³
Vapor Pressure: 0.63 hPa (20 °C)
Flash Point: 88 °C
Partition Coefficient: log Pow 2.25 (calculated)
Stability: Stable under specified storage conditions
Chemical Stability: Stable under recommended handling and storage conditions
Reactivity: Reacts with bases, strong acids, oxidizing agents
Hazardous Decomposition Products: Carbon oxides, hydrogen bromide on combustion
Polymerization: Not expected under normal handling
Conditions to Avoid: Excessive heat, open flame, exposure to moisture, incompatible substances
Likely Routes of Exposure: Inhalation, skin and eye contact, ingestion
Symptoms: Severe irritation, burning, coughing, nausea, headache, gastrointestinal distress
Acutely Toxic Data: LD50 (rat, oral) 300 mg/kg (reference); high degree of toxicity upon ingestion
Long-term Effects: Repeated exposure can cause central nervous system effects, potential liver or kidney damage
Carcinogenicity: Not classified as carcinogen by IARC, NTP, OSHA
Mutagenicity/Teratogenicity: No current data for significant concern, but handle with care due to acute toxicity
Aquatic Toxicity: Harmful to aquatic life, very toxic to fish and invertebrates
Persistence and Degradability: Not readily biodegradable; may persist in environment
Bioaccumulation: May bioaccumulate due to log Pow value; risk to aquatic food chain
Mobility in Soil: Low solubility and volatility suggest moderate mobility
Other Adverse Effects: Potential hazard to aquatic environments, accidental release can cause significant contamination
Waste Treatment Methods: Dispose of using licensed hazardous waste contractor
Incineration: Use controlled incineration with flue gas scrubbing for halogenated waste
Contaminated Containers: Triple rinse and destroy or send to chemical disposal
Do Not: Do not pour down drain, do not dispose of in regular trash
Regulations: Abide by local, state, and national regulations for hazardous chemical disposal
UN Number: UN 2810
UN Proper Shipping Name: Toxic liquid, organic, n.o.s. (Tert-Butyl Bromoacetate)
Transport Hazard Class: 6.1 (Toxic substance)
Packing Group: III
Label: Toxic
Environmental Hazards: Marine pollutant; requires special packaging and mark
Special Precautions: Handle in compliance with dangerous goods requirements; ensure proper containment, documentation; emergency response guide present during transit
TSCA Status: Listed
EINECS/ELINCS: Listed (226-325-6)
OSHA Hazard: Highly toxic chemical per definition of hazardous substance
SARA 302/304: Not listed
SARA 313: Not subject to reporting
Right-to-Know: Listed on relevant state and national inventories
Other International Regulations: Subject to export/import controls and transportation restrictions; comply with REACH regulations if shipped or used in the EU; ensure compliance with specific country standards on workplace exposure, storage, and environmental discharge.
