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Product Name: Teicoplanin
Chemical Formula: C88H97Cl2N9O33
CAS Number: 61036-62-2
EC Number: 262-747-5
Recommended Use: Antibiotic for clinical and laboratory research
Manufacturer: Pharmaceutical suppliers and chemical manufacturers
Emergency Contact: National Poison Center, local emergency services
Synonyms: Targocid, Glycopeptide antibiotic
Molecular Weight: 1879.7 g/mol
Classification: Not classified as hazardous under GHS for normal handling, but may cause health effects to those with sensitivities or allergies
Primary Hazards: Eye and skin irritant, possible respiratory tract irritant, allergenic response in sensitive individuals
Signal Word: Warning
Pictograms: Exclamation mark (irritant)
Hazard Statements: May cause mild irritation to skin and eyes, precaution with dust or aerosol exposure
Precautionary Statements: Use personal protection during handling, avoid inhalation, avoid contact with skin and eyes
Route of Exposure: Inhalation, ingestion, skin/eye contact
Target Organs: Eyes, respiratory system, skin
Chemical Name: Teicoplanin
Purity: ≥90% by HPLC
Impurities: Residual solvents and analogs < 1%
Other Ingredients: Preservative agents and excipients (if supplied in formulated products)
Inhalation: Remove individual to fresh air, keep at rest, seek medical advice if symptoms persist
Skin Contact: Wash skin immediately with soap and plenty of water, remove contaminated clothing, seek attention if irritation occurs
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, consult a physician if irritation develops
Ingestion: Rinse mouth thoroughly with water, seek medical assistance if feeling unwell
Note for Physicians: Treat symptomatically, monitor for allergic reactions in sensitized individuals
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical, or foam
Hazardous Combustion Products: Carbon oxides, nitrogen oxides, hydrochloric acid fumes
Special Protective Equipment: Firefighters should wear full protective gear and self-contained breathing apparatus
Fire/Explosion Risk: Dust can form explosive mixture in air but low risk under standard lab use
Specific Hazards: Avoid inhalation of smoke and combustion byproducts
Personal Precautions: Wear gloves, lab coat, goggles, and dust mask to prevent skin, eye, and respiratory exposure
Spill Cleanup: Avoid raising dust, sweep up and collect in suitable containers, decontaminate affected area with appropriate detergent
Environmental Precautions: Prevent release into drains, surface and ground water, avoid soil contamination
Waste Disposal: Place collected waste in closed, labeled containers for disposal as hazardous waste; comply with local regulations
Handling: Use in well-ventilated area, avoid inhaling dust or mist, avoid direct contact with skin, follow good laboratory hygiene, wash hands thoroughly after handling
Storage Conditions: Store in tightly closed containers, away from incompatible materials, refrigerate or freeze as recommended for stability, protect from light, moisture, and sources of ignition
Incompatibilities: Strong oxidizing agents, acids, bases
Packing Materials: Use containers made of high-density polyethylene or glass, properly labeled
Exposure Limits: No occupational exposure limits assigned for Teicoplanin
Engineering Controls: Local exhaust or general ventilation, safety shower and eyewash station in vicinity
Personal Protection: Chemical-resistant gloves (nitrile suggested), tightly fitting goggles, laboratory coat, appropriate respiratory protection if dust or aerosols likely
Hygiene Measures: Do not eat, drink, or smoke during use; wash hands after handling; remove contaminated clothing immediately
Appearance: White to off-white powder
Odor: Odorless or faint antibiotic smell
pH: 6.0 – 7.5 (aqueous solution, 1% w/v)
Solubility: Freely soluble in water, sparingly soluble in methanol, practically insoluble in ether and chloroform
Melting Point: Decomposes before melting
Boiling Point: Not applicable (decomposes at high temperature)
Vapor Pressure: Not applicable
Density: Not determined
Flash Point: Not applicable
Partition Coefficient: Not determined
Chemical Stability: Stable under recommended storage conditions
Conditions to Avoid: Prolonged exposure to air, light, or elevated temperatures
Incompatible Materials: Strong oxidizing agents, acids, bases
Hazardous Decomposition Products: None under normal use; combustion may release toxic fumes
Polymerization: Will not occur
Acute Toxicity: Low toxicity in animal models by oral, dermal, and inhalation routes
Irritation: Skin and eye irritation possible with extensive or repeated exposure
Sensitization: Allergic reactions (including anaphylaxis) documented in sensitive individuals
Chronic Effects: No data on long-term effects from occupational exposure; clinical use includes risk of nephrotoxicity and ototoxicity in certain patients
Symptoms of Overexposure: Rash, redness, sneezing, coughing, eye watering, respiratory difficulties in sensitive persons
Carcinogenicity: Not listed as carcinogen by IARC, NTP, OSHA
Mutagenicity/Genotoxicity: No evidence observed in standard tests
Reproductive Toxicity: No available evidence for reproductive risk at standard occupational levels
Aquatic Toxicity: May be harmful to aquatic life at high concentrations, avoid discharge into waterways
Persistence and Degradability: Slowly biodegradable in soil and water
Bioaccumulation: Potential for bioaccumulation remains unstudied in detail
Mobility in Soil: Moderately mobile, hazard increases with quantities or repeated release
Other Adverse Effects: No chronic ecological effects reported, but limit release to prevent antimicrobial resistance in the environment
Waste Disposal Methods: Dispose of through licensed chemical waste disposal contractor, follow all local, regional, and national laws
Contaminated Packaging: Treat as hazardous waste, ensure thorough decontamination prior to recycling or disposal
Precautions: Never dispose via sewage or standard landfill, avoid environmental release
UN Number: None assigned for Teicoplanin
Proper Shipping Name: Not regulated as dangerous goods for air, road, or sea transport
Transport Hazard Class: Not classified
Packing Group: Not required
Special Precautions: Protect from physical damage, moisture, and extreme heat during transit
TSCA Status: Not listed
REACH/EC Registration: Exempt as medicinal product; otherwise not registered
OSHA Hazard Communication: Not hazardous under OSHA HazCom Standard
WHMIS Classification (Canada): Not a controlled product
Other Regulatory Listings: Not subject to major international chemical regulations for bulk transport; compliance with local lab safety laws required
