Product Name: Tandospirone Citrate
Chemical Formula: C21H30N4O2·C6H8O7
CAS Number: 112432-23-8
Recommended Use: Pharmaceutical intermediate, research, laboratory reagent
Manufacturer/Supplier Information: See specified supplier contact on shipment paperwork
Emergency Contact Number: Refer to specific local emergency contacts for chemical exposures, fire, or spills
Product Description: Solid powder, pale white to off-white, odorless or slight odor
Classification: Not classified as hazardous under GHS criteria but may cause irritation by inhalation, ingestion, or skin contact
Acute Effects: May irritate eyes, skin, and mucous membranes upon direct contact
Chronic Effects: Prolonged exposure could cause respiratory discomfort or dermatitis
Signal Word: Caution
Hazard Statements: Avoid dust generation, avoid direct skin or eye contact
Pictograms: No pictogram required under GHS
Precautionary Statements: Handle with care, use personal protective equipment tailored for chemical powders
Chemical Name: Tandospirone Citrate
Purity: ≥98%
Synonyms: SM-3997, Sediel
Impurities: Trace solvent residues possible, see COA for additional details
Molecular Weight: 612.72 g/mol
Eye Contact: Rinse thoroughly with water for several minutes, remove contact lenses if present and easy, seek medical attention if irritation persists
Skin Contact: Wash with plenty of soap and water, remove contaminated clothing, consult physician if symptoms develop
Inhalation: Move to fresh air, support breathing if necessary, seek medical attention if symptoms develop
Ingestion: Rinse mouth, do not induce vomiting unless directed by medical personnel, seek medical advice
Specific Treatments: Immediate decontamination with water recommended for splashes, observation recommended for ingestion or prolonged exposure
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Media: Direct water jet on powder can cause dispersal
Specific Hazards: Combustion products may include carbon monoxide, nitrogen oxides, and irritant fumes
Protective Equipment: Self-contained breathing apparatus, protective suit
Special Procedures: Avoid dust generation during firefighting, control run-off water to prevent environmental contamination
Personal Precautions: Wear appropriate personal protective equipment, including gloves, safety goggles, and lab coat
Environmental Precautions: Prevent entry into sewers and watercourses, minimize environmental release
Containment Methods: Avoid creating airborne dust, cover spill with absorbent material
Cleanup Procedures: Collect into appropriate labeled container for chemical waste disposal, ventilate area, decontaminate surfaces with detergent solution
Handling Precautions: Handle within chemical fume hood or with adequate ventilation, avoid direct skin and eye contact, wear suitable protection
Incompatible Materials: Strong oxidizing agents, strong acids and bases
Storage Requirements: Store in original container, tightly sealed, in a cool and dry environment at 2–8°C, away from direct sunlight and incompatible substances
Hygiene Measures: Do not eat, drink, or smoke in working area, wash hands thoroughly after handling
Exposure Limits: No established occupational exposure limits
Engineering Controls: Use with local exhaust ventilation, keep containers tightly closed when not in use
Personal Protection: Safety goggles, chemical-resistant gloves, laboratory coat or gown, and respiratory protection if dust is generated
Additional Hygiene Measures: Avoid unnecessary exposure, launder contaminated clothing before reuse
Appearance: White to off-white crystalline powder
Odor: Odorless or very faint
pH: No data available in aqueous solution
Melting Point/Freezing Point: 162–167°C (decomposes)
Solubility in Water: Freely soluble
Boiling Point: Not applicable (decomposes before boiling)
Vapor Pressure: Not applicable
Flash Point: Not established
Partition Coefficient (log Kow): Data unavailable
Auto-ignition Temperature: Data unavailable
Decomposition Temperature: Above melting point
Viscosity: Not applicable (solid)
Chemical Stability: Stable under recommended storage conditions
Reactivity: Not reactive under normal laboratory and storage conditions
Conditions to Avoid: High temperatures, moisture, incompatible chemicals
Incompatible Materials: Strong acids, bases, and oxidizing agents
Hazardous Decomposition Products: Carbon dioxide, carbon monoxide, nitrogen oxides, and organic fumes under fire conditions
Polymerization: No hazardous polymerization reported
Likely Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Acute Toxicity: No human data, no LD50 values established, low acute oral toxicity predicted based on structure
Skin Irritation: May cause mild irritation
Eye Irritation: May cause discomfort and redness
Respiratory Effects: Dust inhalation could provoke irritation or coughing
Sensitization: No data suggesting sensitization
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Mutagenicity/Teratogenicity: No mutagenic or teratogenic effects reported in standard studies
Eco-toxicity: No specific eco-toxicity data available, structure suggests low environmental hazard at laboratory scale
Aquatic Effects: No evidence of acute harm to aquatic life from available information
Persistence and Degradability: Likely biodegradable over moderate timeframes, but detailed data missing
Bioaccumulative Potential: No evidence of significant bioaccumulation
Mobility in Soil: Expected to have low to moderate mobility, water solubility implies runoff possible
Other Adverse Effects: Avoid uncontrolled environmental release, observe local regulations regarding pharmaceutical waste
Waste Treatment Methods: Collect and deliver to approved chemical disposal facility, follow local or national environmental protection guidelines
Disposal of Contaminated Packaging: Rinse, deface labels, and dispose as chemical waste
Special Precautions: Never dispose via sink or general trash, minimize environmental exposure
Ecological Concerns: Avoid contamination of surface water or groundwater
UN Number: Not assigned
Proper Shipping Name: Chemical, N.O.S. (not otherwise specified)
Transport Hazard Class: Not regulated as dangerous goods
Packing Group: No specific packing requirements identified
Special Transportation Notes: Transport in sealed containers, avoid sources of heat, moisture, and mechanical damage
Inventory Listings: Not listed on US TSCA, EU EINECS, or other general chemical inventories for commercial use
Labeling Requirements: Comply with workplace and laboratory labeling rules for non-hazardous pharmaceuticals
Specific Legislation: Review national drug and chemical control acts in user’s jurisdiction
Occupational Safety Regulations: OSHA Laboratory Standard applicability in the United States
Other Regulatory Compliance: FDA and local health authorities may regulate usage depending on research or pharmaceutical context