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Product Name: Sulfathiazole
Chemical Formula: C9H9N3O2S2
CAS Number: 72-14-0
Other Names: 4-Amino-N-(thiazol-2-yl) benzenesulfonamide
Recommended Use: Antibacterial agent, laboratory chemical
Supplier Contact: Emergency phone numbers provided according to local jurisdiction, usually available on product label or company website
Synonyms: 2-Sulfanilamidothiazole, Sulfapyridine thiazole analog
UN Number: Not classified as hazardous for transport under most regulations
Intended Users: Laboratory staff, medical research, trained professionals in relevant industries
Classification: Acute toxicity (oral, dermal, inhalation), possible skin and eye irritant, respiratory sensitizer
Signal Word: Warning
Hazard Statements: May cause an allergic skin reaction, harmful if swallowed, inhaled or absorbed through skin
Pictograms: Exclamation mark
Precautionary Statements: Avoid breathing dust, use gloves and eye protection, wash thoroughly after handling
Route of Exposure: Oral, dermal, inhalation
Potential Health Effects: Allergic reactions like rash, swelling, breathing difficulties, headaches, nausea
Chronic Effects: Repeat exposure can lead to increased sensitivity and risk of more severe allergic reactions
Regulatory Listing: Listed on many chemical inventories, not classed as carcinogen or mutagen by IARC, NTP, or EPA
Chemical Identity: Sulfathiazole
Concentration: >99% active ingredient by weight
Impurities: Generally less than 1%, may include related sulfonamide compounds
Other Ingredients: None significant under standard formulations
Molecular Weight: 255.32 g/mol
EC Number: 200-773-6
Relevant Purity: Pharmaceutical or analytical, depending on source
Reference Standards: Meets industry standards for laboratory or pharmaceutical grade
General: Remove contaminated clothing immediately, move to fresh air
Inhalation: Take victim to fresh air, keep at rest and seek medical advice if symptoms persist
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing and wash before reuse, seek medical attention for persistent irritation
Eye Contact: Flush with plenty of water for 15 minutes, lift eyelids occasionally, seek medical attention if irritation persists
Ingestion: Rinse mouth, seek immediate medical attention, do not induce vomiting
Medical Attention: Symptomatic treatment recommended, notify health care providers of chemical exposure
Note for Doctors: Monitoring for delayed allergic or hypersensitivity is advised
Suitable Extinguishing Media: Water spray, dry chemical, foam, CO2 extinguishers
Specific Hazards: May emit toxic fumes of sulfur oxides, nitrogen oxides during combustion
Special Protective Equipment: Wear self-contained breathing apparatus and protective suit
Explosion Hazard: Fine dust may form explosive mixtures with air
Advice for Firefighters: Use full protective gear, avoid inhaling combustion by-products, keep containers cool with water spray
Personal Precautions: Use personal protective equipment, evacuate area if dust concentrations are high
Spillage Response: Avoid generating dust, sweep up and place in suitable chemical waste container
Environmental Precautions: Prevent entry to drains, sewers, waterways
Cleanup Methods: Mop up with damp cloth or inert absorbent; ventilate area; dispose material in accordance with regulations
Decontamination: Wash affected area with soap and water after cleanup, disinfect surfaces if necessary
Disposal of Spills: Dispose via licensed waste contractor
Handling: Minimize dust generation, handle with chemical-resistant gloves, safety goggles, avoid skin and eye contact
Storage Conditions: Store tightly sealed in a dry, cool, well-ventilated area
Incompatible Materials: Strong oxidizing agents, strong acids, alkaline substances
Avoid: High humidity, opens flames, sources of ignition
Special Precautions: Keep containers tightly closed, use only with appropriate exhaust ventilation, wash hands after use
Exposure Limits: Occupational exposure limits not established for Sulfathiazole, maintain exposure as low as reasonably achievable
Engineering Controls: Chemical fume hood, adequate general or local exhaust
Personal Protection: Chemical-resistant gloves, laboratory coat, splash-proof safety goggles, dust mask or respirator when high concentrations cannot be avoided
Hygiene Measures: Wash hands before breaks and at end of workday, do not eat, drink, or smoke in work areas
Environmental Controls: Use appropriate containment to prevent environmental release
Appearance: White to pale yellow crystalline powder
Odor: Odorless or faint characteristic odor
pH: Slightly acidic to neutral in solution
Melting Point: 196-200 °C
Boiling Point: Decomposes prior to boiling
Solubility: Slightly soluble in water; readily soluble in acetone, alcohol, and dilute acids
Density: Around 1.45 g/cm³
Flash Point: Not easily flammable
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): Estimated as low, substance prefers water to fat
Evaporation Rate: Not applicable under normal use conditions
Chemical Stability: Stable under normal storage and handling conditions
Hazardous Reactions: Reacts with strong oxidizers, forms potentially harmful compounds
Incompatible Materials: Strong acids and alkalis, oxidizing agents
Conditions to Avoid: High temperature, moisture, direct sunlight
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, toxic fumes in case of fire or decomposition
Acute Toxicity: LD50 Oral (rat): approximately 14,000 mg/kg
Skin Sensitization: Reported in some individuals with repeated exposure
Eye Irritation: May cause irritation, redness, discomfort
Chronic Effects: Prolonged exposure can exacerbate sensitivity and trigger allergies
Mutagenicity: No mutagenic effects noted in standard bacterial and mammalian tests
Carcinogenicity: Not designated as a human carcinogen by IARC, NTP, OSHA
Reproductive Effects: Not classified as reproductive toxicant, though animal data points to cautious use among pregnant persons
Other Adverse Effects: Rarely, can provoke severe hypersensitivity or systemic effects in sensitive individuals
Ecotoxicity: Harmful to aquatic organisms at high concentrations
Persistence and Degradability: Moderately persistent in environment; slow biodegradation
Bioaccumulative Potential: Not expected to bioaccumulate in aquatic organisms or plants
Mobility in Soil: Moderate mobility, risk of groundwater contamination if large amounts released
Aquatic Toxicity (LC50, EC50): Data limited; careful control of waste discharges advised
Other Environmental Concerns: Anti-bacterial properties may disrupt microbial ecosystems and wastewater treatment
Disposal Method: Dispose as hazardous waste according to local, regional, national, and international regulations
Packaging Disposal: Clean containers if possible, recycle or dispose in compliance with applicable laws
Do Not: Discharge to environment or sewage
Incineration: Under controlled conditions; release of sulfur and nitrogen oxides to be minimized
Special Precautions: Consult local waste authorities; labeling and identification on waste packages required
UN Number: Not regulated as dangerous for transport under ADR, IMDG, IATA
Proper Shipping Name: Sulfathiazole
Transport Hazard Class: Not classified as hazardous
Packing Group: Not assigned
Special Precautions: Keep containers sealed, avoid spillage in transit
Labeling: No special hazard labeling required, but product labels should include product identification and hazard warnings as per workplace regulations
Chemical Inventory Status: Listed on TSCA (US), EINECS (EU), DSL (Canada) and other major chemical inventories
Workplace Regulation: Hazard communication standards apply—ensure Safety Data Sheet available to relevant staff
Other Regulatory Listings: Not regulated as carcinogen, mutagen, or reproductive toxin
Environmental Regulation: Subject to local and national requirements for hazardous waste and chemical discharge
Country-Specific Regulations: Requirements for use, disposal, labeling and reporting may vary widely; check with health, safety, and environmental authorities
