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Product Name: Sulfadimidine
Chemical Name: 4-amino-N-(4,6-dimethyl-2-pyrimidinyl)benzenesulfonamide
Common Synonyms: Sulfamethazine, Sulfadimidin, Sulfadimerazine
CAS Number: 57-68-1
Recommended Uses: Veterinary pharmaceutical; Antimicrobial agent
Manufacturer/Importer Details: Contact pharmaceutical supplier for specific name and address
Emergency Contact Number: Refer to local or national poison control center
Classification: Acute Toxicity (Oral): Category 4, Eye Irritation: Category 2A, Skin Sensitization: Category 1
Hazards: Harmful if swallowed, may cause eye irritation, can provoke allergic skin reactions, may cause respiratory irritation in sensitive individuals
Pictograms: Exclamation mark
Signal Word: Warning
Hazard Statements: Causes mild to moderate irritation to eyes and skin, toxic if ingested in sufficient quantities, prolonged or repeated exposure can cause allergic responses
Precautionary Statements: Avoid dust formation, use with adequate ventilation, wear suitable protective clothing
Chemical Identity: Sulfadimidine
Molecular Formula: C12H14N4O2S
Molecular Weight: 278.33 g/mol
Concentration: 100% (pure substance in technical grade)
Impurities: Typically less than 1% unidentified related substances
Inhalation: Remove from exposure to fresh air, keep at rest, seek medical attention if respiratory symptoms appear
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water, seek medical advice if irritation develops
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, get medical help for persistent discomfort
Ingestion: Never induce vomiting, rinse mouth, seek immediate medical attention, show product label or safety data sheet to medical personnel
Main Symptoms: Rash, eye redness, coughing, nausea, allergic reactions in sensitized individuals
Suitable Extinguishing Media: Water spray, dry chemical powder, carbon dioxide, foam
Specific Hazards: Decomposes to yield toxic fumes such as nitrogen oxides, sulfur oxides, carbon oxides
Protective Equipment: Firefighters use self-contained breathing apparatus and full protective clothing
Additional Instructions: Move containers away from fire if safe to do, prevent water runoff from contaminating waterways
Exposure Risks: Inhalation of decomposition products can be hazardous to health
Personal Precautions: Wear protective gloves, clothing, eye protection, avoid inhaling dust, ventilate area
Environmental Precautions: Do not allow product to enter drains, surface water, or soil
Methods for Containment and Cleaning Up: Sweep up spill using inert non-combustible material, collect in labeled containers for disposal, wash contaminated surfaces
Disposal: Dispose of collected material in accordance with local regulations for hazardous waste
Monitoring: Ensure area is completely free of residue before permitting access without protection
Handling: Avoid generating airborne dust, use local exhaust ventilation, prevent contact with skin, eyes, and clothing, wash thoroughly after use, keep containers tightly closed
Storage: Store in original container, keep in cool, dry, well-ventilated location, protect from direct sunlight, keep away from incompatible materials such as strong oxidizers and alkalis
Storage Conditions: Store below 25°C, keep away from food, feed and drinking water
Incompatibilities: Strong acids, bases, oxidizing agents
Exposure Limits: No established occupational exposure limits for sulfadimidine by OSHA, NIOSH, or ACGIH
Engineering Controls: Use process enclosures, fume hood, or other engineering controls to limit exposure
Personal Protection: Wear chemical-resistant gloves (nitrile or PVC), safety goggles, lab coat, use appropriate dust mask or respirator if airborne exposure risk exists
Hygiene Measures: Wash hands before eating or drinking, remove contaminated clothing before entering eating areas, do not smoke in work area
Appearance: White to off-white crystalline powder
Odor: Slight, characteristic odor
Odor Threshold: Not established
pH (1% solution): 6.5 – 7.5
Melting Point: 196–200°C
Boiling Point: Not applicable (decomposes)
Flash Point: Not flammable
Evaporation Rate: Not applicable
Flammability: Not flammable under normal conditions
Explosive Properties: Not expected
Vapor Pressure: Negligible at ambient temperature
Solubility in Water: 1.6 g/L at 20°C
Partition Coefficient (n-octanol/water): LogP ~0.11
Density: 1.34 g/cm³
Other Data: Stable under standard conditions
Chemical Stability: Stable in closed containers at ambient temperatures
Conditions to Avoid: High humidity, extreme heat, exposure to direct sunlight
Materials to Avoid: Strong acids, strong oxidizing agents, strong bases
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Reactivity: No explosive or self-reactive properties observed under normal handling and storage
Acute Toxicity: LD50 (oral, rat): ~2000 mg/kg
Chronic Effects: May cause allergic reactions on repeated skin contact, risk of blood dyscrasia (agranulocytosis, hemolytic anemia) in predisposed individuals
Skin and Eye Irritation: Can produce mild to moderate irritation
Inhalation: Dust may irritate respiratory tract
Carcinogenicity: Not classified as carcinogenic to humans by IARC, ACGIH, NTP, or OSHA
Reproductive Toxicity: Limited evidence for developmental toxicity in animal studies at very high doses
Other Information: Overexposure linked to hypersensitivity reactions, such as rash, fever
Ecotoxicity: Harmful to aquatic organisms at high concentrations, may disrupt microbial activity in soil and water
Persistence and Degradability: Degrades slowly in soil and water, potential for accumulation in aquatic environments
Bioaccumulation Potential: Low potential for bioaccumulation (low logP)
Mobility in Soil: Moderate mobility, soluble in water, may leach through soil
Other Adverse Effects: Potential for antibiotic resistance development in environmental bacteria when released in significant amounts
Disposal Methods: Dispose of product in accordance with local, regional, or national regulations; use authorized chemical waste disposal services
Packaging Disposal: Rinse empty containers before disposal, triple rinse when possible, send to licensed reconditioner or supplier
Special Precautions: Do not allow product to enter public waterways, avoid contamination of soil
Waste Codes: Not specifically listed in US RCRA, handle as pharmaceutical waste
UN Number: Not regulated as dangerous goods for air, road, or sea transport
Proper Shipping Name: Sulfadimidine (not dangerous goods)
Transport Hazard Class: Not classified
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions: Protect containers from physical damage and keep upright during transport
US TSCA: Listed
EU REACH: Registered
US OSHA: This chemical is not considered hazardous under OSHA Hazard Communication Standard
SARA Title III Sec.302/313: Not listed
California Prop 65: Not listed as a cancer or reproductive toxin
Other Information: Compliance with all applicable regulations required, some regions may classify as prescription-only medicine, veterinary use subject to residue control in animal products
