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MSDS for Sulfachloropyrazine Sodium

Identification

Product Name: Sulfachloropyrazine Sodium
Chemical Formula: C9H8ClN4NaO2S
Synonyms: Sodium Sulfachloropyrazine
CAS Number: 23282-55-5
Recommended Uses: Veterinary pharmaceutical, antiparasitic agent
Supplier Information: Manufacturer’s name, address, and emergency contact phone number provided by the specific supplier
Emergency Overview: White to pale yellow powder, slight odor, supplied mainly as a technical or formulated powder

Hazard Identification

Classification: Harmful if swallowed, potential skin and eye irritant, possible respiratory sensitizer
Label Elements: Signal word “Warning” on label, hazard pictograms for health hazard and exclamation mark
Hazard Statements: H302: Harmful if swallowed; H315: Causes skin irritation; H319: Causes serious eye irritation; H334: May cause allergy or asthma symptoms or breathing difficulties
Precautionary Statements: Wash hands after handling, avoid breathing dust, use only outdoors or in a well-ventilated area, wear protective gloves and eye protection
Unusual Hazards: Some evidence of potential reproductive toxicity based on animal studies, long-term exposure linked to hematological effects in laboratory animals

Composition / Information on Ingredients

Chemical Name: Sulfachloropyrazine Sodium
Percentage by Weight: >95% active ingredient
Impurities: Sodium chloride, process-related residuals, trace of unreacted sulfonamide derivatives
Other Components: Not considered hazardous under current regulatory criteria

First Aid Measures

Inhalation: Move person to fresh air, keep at rest in comfortable position, seek medical attention for coughing or breathing difficulty
Skin Contact: Remove contaminated clothing, wash affected skin area with soap and water for at least 20 minutes, seek medical advice if irritation persists
Eye Contact: Immediately flush eyes with plenty of running water for 15 minutes, lifting upper and lower lids occasionally, remove contact lenses if present
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical personnel, seek immediate medical evaluation
Advice to Physicians: Treat symptomatically, monitor for allergic or hypersensitivity reactions, administer supportive care if required

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, carbon dioxide, foam, water spray
Unsuitable Media: Strong water streams may cause contamination spread
Hazardous Combustion Products: Emits toxic fumes of nitrogen oxides, sulfur oxides, hydrochloric acid, and sodium oxides during combustion
Protective Equipment: Firefighters need self-contained breathing apparatus and protective clothing
Special Procedures: Cool surrounding containers with water, prevent runoff from entering drains or water sources, evacuate area if necessary due to toxic gases

Accidental Release Measures

Personal Precautions: Wear NIOSH-approved respirator, chemical-resistant gloves, eye protection, minimize dust generation
Environmental Precautions: Prevent powder from entering watercourses or drains, avoid contaminating soil, report large releases to local authorities
Methods for Cleanup: Carefully sweep up spilled material without creating dust, place in appropriate waste disposal container for collection, rinse area with water and detergent, ventilate affected area after cleanup

Handling and Storage

Handling: Avoid inhaling dust or direct contact with skin and eyes, use only with adequate ventilation, handle with care to keep container tightly closed
Storage Requirements: Store in tightly sealed original containers, cool dry well-ventilated place, away from incompatible substances such as acids and oxidizing agents
Specific Storage Details: Protect from moisture and direct sunlight, keep out of reach of children and animals, avoid excessive stacking to prevent container breakage

Exposure Controls and Personal Protection

Exposure Limits: No official occupational exposure limits set by OSHA or ACGIH
Engineering Controls: Use local exhaust ventilation where dust may be generated, maintain positive airflow to limit accumulation
Personal Protective Equipment: Wear chemical-resistant gloves (nitrile or neoprene), safety goggles, protective clothing (lab coat or coveralls), NIOSH/MSHA approved respirator if exposure limits exceeded or dust present
Additional Precautions: No eating or drinking in work areas; always wash hands thoroughly after handling

Physical and Chemical Properties

Appearance: White to pale yellow powder or granules
Odor: Faint, unremarkable odor
pH (1% Solution): Around 8–10
Melting Point: Decomposes above 250°C
Solubility: Freely soluble in water
Relative Density: About 1.55 g/cm³
Partition Coefficient (log Kow): Not significantly lipophilic, low to moderate mobility in the environment
Vapor Pressure: Negligible at room temperature
Boiling Point: Not applicable (decomposes before boiling)
Flash Point: Not flammable

Stability and Reactivity

Chemical Stability: Stable under normal conditions of storage and use, decomposes with prolonged heat or exposure to strong sunlight
Conditions to Avoid: High temperature, moisture, exposure to strong oxidizing agents and acids
Incompatible Materials: Strong oxidizers, acids, bases
Hazardous Decomposition Products: Toxic fumes including nitrogen oxides, sulfur oxides, sodium oxides, possible trace chlorine compounds
Polymerization: No risk of hazardous polymerization

Toxicological Information

Routes of Exposure: Inhalation, ingestion, skin and eye contact
Acute Toxicity: LD50 (oral, rat): 3,000–5,000 mg/kg; may cause gastrointestinal upset, nausea, vomiting, diarrhea
Skin Sensitization: Evidence of allergy or dermatitis with repeated/prolonged contact
Eye Effects: Irritation, redness, pain with direct contact
Chronic Effects: Prolonged exposure can impact blood parameters, minor effects seen in animal reproduction studies, not classified conclusively as a carcinogen
Other Data: No evidence of mutagenicity or carcinogenicity in standard animal bioassays, not proven teratogenic, possible idiosyncratic drug reactions in some humans

Ecological Information

Ecotoxicity: Moderate toxicity to aquatic invertebrates and fish, EC50 (Daphnia magna): 12–30 mg/L over 48 hours
Persistence and Degradability: Degrades slowly under natural conditions, moderate bioaccumulation risk
Mobility in Soil: Leachable in water-saturated soils due to high water solubility, binds weakly to organic matter
Other Environmental Hazards: Harmful to aquatic life with long lasting effects, risk for secondary poisoning in non-target organisms through food chain
Precaution: Avoid application near waterways, observe local guidelines regarding veterinary pharmaceutical residues

Disposal Considerations

Waste Disposal Methods: Dispose as hazardous pharmaceutical waste through authorized contractor, incinerate in licensed facility, comply with local legislation
Container Disposal: Triple rinse and offer for recycling or puncture and dispose in approved landfill (do not reuse containers for other purposes)
Special Precautions: Do not contaminate water, food, or feed by waste disposal; avoid uncontrolled release into the environment

Transport Information

UN Number: Not classified as dangerous goods under UN Model Regulations
Proper Shipping Name: Not regulated
Transport Hazard Class: Not assigned
Packing Group: Not required
Marine Pollutant: Not regulated as marine pollutant, but recommended to avoid bulk shipment near sensitive environments
Special Transport Precautions: Transport in original packaging, avoid exposure to moisture or extreme heat, secure to prevent movement

Regulatory Information

Labelling Requirements: Comply with relevant OSHA/GHS hazard communication standards for workplace chemicals
Inventory Listings: Listed in major pharmacopoeias; regulated as veterinary active substance in various jurisdictions
TSCA Status: Exempt as pharmaceutical active, check local reporting obligations
EU Classification: Regulation (EC) No 1907/2006 (REACH) and Regulation (EC) No 1272/2008 (CLP) apply for substances handled in Europe
Other Regulation: Follow waste handling acts, pharmaceutical and environmental residue control requirements, check for updates on usage restrictions or residue limits in food-producing animals