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Product Name: Sulfacetamide Sodium Monohydrate
Chemical Formula: C8H9N2NaO3S·H2O
Chemical Family: Sulfonamide
Synonyms: Sodium Sulfacetamide Hydrate
CAS Number: 6209-17-2
Intended Use: Pharmaceutical ingredient, topical antibacterial
Manufacturer: Available from multiple pharmaceutical suppliers, details as per labeling
Emergency Contact: Refer to local poison control center or manufacturer emergency line
Recommended Restrictions: Professional and industrial use only
GHS Classification: Eye irritation, Category 2A
Signal Word: Warning
Pictograms: Exclamation mark
Hazard Statements: Causes serious eye irritation, may cause skin irritation, may cause respiratory tract irritation
Precautionary Statements: Avoid breathing dust, wear protective gloves and eye protection, wash thoroughly after handling
Potential Health Effects: Inhalation may cause coughing and sneezing, direct contact with eyes may lead to redness and discomfort, ingestion could upset stomach
Environmental Impact: See ecological section for toxicity data, minimize release to environment
Chemical Name: Sulfacetamide Sodium Monohydrate
CAS Number: 6209-17-2
Percent: 98–100%
Impurities: Water of hydration (approx. 7.8%), trace process residues
Additives: None typically present
Inhalation: Move subject to fresh air, provide respiratory support if breathing is difficult, seek medical advice for any lasting symptoms
Skin contact: Wash skin gently with soap and plenty of water, remove any contaminated clothing, seek medical attention for persistent irritation
Eye contact: Rinse cautiously with water for at least 15 minutes, keep eyelids open, consult an eye specialist if irritation remains
Ingestion: Rinse mouth, drink water to dilute, do not induce vomiting, seek medical guidance if large amounts have been swallowed
Most Important Symptoms/Effects: May cause local irritation, burning, stinging, or redness
Note to Physician: Treat symptomatically, control exposure, supportive care as needed
Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Unsuitable Extinguishing Media: Avoid straight streams of water
Hazards from Combustion: Emits toxic fumes such as nitrogen oxides, sulfur oxides, and carbon monoxide on burning
Protective Equipment: Self-contained breathing apparatus, full protective clothing
Advice for Firefighters: Use caution, avoid inhaling smoke, evacuate area if large quantities involved
Special Procedures: Cool exposed containers with water mist, control run-off to prevent environmental contamination
Personal Precautions: Wear gloves, goggles, and dust respirator, avoid contact and inhalation
Environmental Precautions: Prevent spill from entering drains or waterways, collect for proper disposal
Methods for Cleaning Up: Sweep or scoop spilled material, place into labeled containers, clean area thoroughly with water
Reference to Other Sections: For personal protection see Section on Exposure Controls
Safe Handling: Avoid creation of dust, use with adequate ventilation, do not eat or drink while working with material
Storage Conditions: Store in closed, labeled containers in a cool, dry, well-ventilated area, protect from excessive heat or freezing
Incompatibilities: Strong oxidizing agents, acids
Specific End Use: For industrial or research use as indicated by product label, follow workplace protocols
Occupational Exposure Limits: No published limits for sulfacetamide sodium, general dust limit: 10 mg/m³ (nuisance dust, OSHA PEL)
Engineering Controls: Local exhaust or general ventilation to minimize airborne concentrations
Personal Protection: Protective gloves (nitrile recommended), chemical splash goggles, lab coat
Respiratory Protection: Use dust mask or respirator if exposure may exceed limits
Hygiene Measures: Wash hands and face after handling, do not eat, drink, or smoke around the substance
Appearance: White, crystalline powder
Odor: Slight characteristic odor
Odor Threshold: Not established
pH (1% solution): 8–10
Melting Point: 185–190°C (decomposes)
Boiling Point: Decomposes before boiling
Flash Point: Not available
Flammability: Not classified as highly flammable
Solubility: Soluble in water
Partition Coefficient (log Kow): Not available
Vapor Pressure: Negligible at room temperature
Density: Approximately 1.3 g/cm³
Decomposition Temperature: >185°C
Viscosity: Not applicable
Evaporation Rate: Not relevant for solid
Chemical Stability: Stable under standard conditions, shelf stable in closed containers
Possibility of Hazardous Reactions: Not likely under normal processing
Incompatible Materials: Strong oxidizers, strong acids, may react with halogens
Hazardous Decomposition Products: Sulfur oxides, nitrogen oxides, possible toxic gases on burning
Conditions to Avoid: Excessive heat, moisture ingress
Acute Toxicity: Oral LD50 (rat): approx. 16,000 mg/kg
Skin Corrosion/Irritation: May cause skin irritation with repeated exposure
Eye Damage/Irritation: Can cause moderate to severe irritation
Respiratory Effects: Prolonged dust inhalation may irritate airways
Chronic Exposure: Sensitization, allergies or skin reactions seldom reported in medical use
Carcinogenicity: Not classified as carcinogen (IARC, EPA)
Mutagenicity: Not expected to be mutagenic at therapeutic doses
Reproductive Toxicity: No specific data available; caution advised
Medical Conditions Aggravated by Exposure: Sulfonamide hypersensitivity, asthma, respiratory disorders
Toxicity to Aquatic Life: Ecotoxicity data sparse, sulfonamides may harm aquatic microorganisms with prolonged exposure
Persistence and Degradability: Not rapidly degraded in environment, persistent by some accounts
Bioaccumulation: Potential for bioaccumulation appears low based on chemical properties
Mobility in Soil: Highly soluble, could move through soil to groundwater
Other Adverse Effects: Avoid release to the environment, antibiotic residues may disrupt microbial ecosystems
Product Disposal: Treat as non-hazardous chemical waste, follow local or national regulations, consult licensed waste processor
Contaminated Packaging: Wash and reuse if permitted locally, otherwise discard with chemical waste
Special Precautions: Prevent entry to water systems, secure containers during transit or storage
UN Number: Not regulated for transport under ADR/RID, IMDG, IATA
Transport Hazard Class: Not classified as dangerous good
Packing Group: Not assigned
Shipping Description: Sulfacetamide sodium monohydrate, white crystalline powder
Environmental Hazards: Not a marine pollutant
Special Precautions: Store upright, avoid rough handling, consign according to local guidelines
TSCA Status: Listed
EPCRA Section 302/304: Not subject
SARA 313: Not subject
California Prop 65: Not listed as a carcinogen or reproductive toxin
REACH: Registered for professional and industrial use
Other: Medicine regulations or workplace controls may apply, refer to relevant national or regional legislation for additional details
