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Product Name: Sulbactamic Acid
Synonyms: β-lactamase inhibitor Sulbactam, Sulbactamic Acid
Chemical Formula: C8H11NO5S
Chemical Family: β-lactamase Inhibitors
Intended Use: Pharmaceutical intermediate for antibiotic therapies
Supplier Details: Manufacturer or distributor name, address, emergency phone
Recommended Restrictions: Restricted to trained personnel, not for household or amateur use
Classification: Eye irritation (Category 2), Skin irritation (Category 2), Respiratory sensitizer (Category 1)
GHS Label Elements: Warning, Exclamation mark
Potential Health Effects: Irritation to eyes and skin, respiratory symptoms including coughing and shortness of breath, allergic skin reaction
Potential Environmental Effects: Harmful to aquatic life, possibility of contamination in waterways
Routes of Exposure: Inhalation, skin/eye contact, accidental ingestion
Symptoms: Redness, itching, discomfort, respiratory distress
Chemical Identity: Sulbactamic Acid
CAS Number: 68373-14-8
Impurities: Less than 1% β-lactam analogs, solvents from manufacturing process
Purity: More than 98.5% (pharmaceutical grade)
Molecular Weight: 233.24 g/mol
Inhalation: Remove exposed individual to fresh air, monitor for respiratory difficulties, obtain medical advice if symptoms persist
Skin Contact: Wash thoroughly with soap and water, remove contaminated clothing, consult a physician if reaction persists
Eye Contact: Rinse opened eyes with plenty of water for at least 10 minutes, remove contact lenses, seek immediate medical attention
Ingestion: Do not induce vomiting, rinse mouth, call a poison control center or physician for further guidance
Note for Physicians: Treat symptomatically, evaluate risk of allergic or respiratory sensitization
Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Special Hazards: Toxic or irritating gases including sulfur oxides, nitrogen oxides may be released during combustion
Advice for Firefighters: Wear self-contained breathing apparatus and full protective gear, avoid inhaling smoke or fumes
Explosion Risk: No special risk of explosion expected under standard storage
Personal Precautions: Use standard chemical-resistant gloves, eye protection, laboratory coat, avoid breathing dust
Environmental Precautions: Prevent entry into sewers, drains, or water bodies; notify authorities as required
Methods and Materials for Containment: Absorb spilled material with inert absorbent, sweep up carefully to avoid dust
Cleanup Procedures: Collect in suitable, tightly sealed containers for disposal, ventilate area, clean surfaces with water and detergent
Safe Handling: Handle only in chemical fume hood or well-ventilated area, wear suitable protective equipment
Hygiene Measures: Avoid eating, drinking, or smoking near work area; wash hands thoroughly after handling
Storage Conditions: Store in cool, dry, well-ventilated area away from incompatible materials such as strong oxidizers or acids
Containers: Use tightly sealed, non-reactive containers
Protection Against Physical Damage: Store away from sources of flame or direct sunlight
Engineering Controls: Use chemical fume hoods, local exhaust ventilation to minimize airborne contamination
Occupational Exposure Limits: No specific occupational exposure limit, limit airborne dust as for nuisance particulates
Personal Protection: Safety goggles, chemically resistant gloves, disposable lab coat, respiratory protection if dust or aerosol generation is possible
Environmental Exposure: Ensure effluent complies with local environmental regulations to prevent contamination
Physical State: Solid, crystalline powder
Color: White to off-white
Odor: Odorless or faint characteristic odor
pH: 3–6 (1% solution in water)
Melting Point: 160–165°C
Boiling Point: Decomposes before boiling
Solubility: Freely soluble in water, sparingly soluble in ethanol
Vapor Pressure: Negligible at room temperature
Flash Point: Not applicable (decomposes)
Partition Coefficient: log Pow -1.6 (estimated)
Chemical Stability: Stable under recommended use and storage conditions
Conditions to Avoid: Moisture, high temperatures, exposure to light
Incompatible Materials: Strong acids, bases, oxidizing agents, alkali metals
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides under fire conditions
Polymerization: Not expected under normal circumstances
Acute Toxicity: Oral LD50 (rat): > 2000 mg/kg, low acute toxicity
Chronic Toxicity: No established chronic toxicity in humans, avoid prolonged or repeated exposure
Known Effects: Mild skin and eye irritation, potential respiratory allergic reaction in sensitive individuals
Carcinogenicity: No data available indicating carcinogenic risk
Mutagenicity: No evidence from animal tests
Reproductive Toxicity: No confirmed risk in humans, better to minimize incidental exposure
Sensitization: May cause allergic skin reaction in certain individuals
Ecotoxicity: Harmful to aquatic organisms based on structurally related compounds
Persistence and Degradability: Partially biodegradable, but may persist in environment if not properly disposed
Bioaccumulation: Low potential for bioaccumulation
Mobility in Soil: High mobility due to water solubility
Other Effects: Discharge into waterways or soil can disrupt local microbial ecologies
Disposal Methods: Dispose of in accordance with local regulatory requirements for chemical waste
Contaminated Packaging: Triple rinse and offer for recycling or disposal at approved facilities
Precautionary Measures: Do not attempt to flush large volumes into sewer; small laboratory quantities can be diluted and neutralized, then handled as normal chemical waste
Special Instructions: Keep clear records of disposal for reporting under pharmaceutical waste tracking regulations
UN Number: Not assigned (non-hazardous for ground transport under standard shipment conditions)
Transport Hazard Class: Not regulated
Proper Shipping Name: Sulbactamic Acid or related compound
Packing Group: Unregulated, use good industrial packaging
Special Precautions for Transport: Avoid moisture ingress, vibration, heat sources; mark packaging for pharmaceutical materials
TSCA Status: Not listed for commercial distribution in the United States except as research or pharmaceutical product
REACH Compliance: Requires registration for importation into the EU above required tonnage
OSHA Status: Not listed as hazardous by OSHA, yet standard laboratory safety guidelines apply
Other Regulations: Subject to pharmaceutical codes, controlled substance documentation, and chemical import/export restrictions as appropriate by region
Warning Labels: Chemical reagent, not for food or feed use, restricted laboratory use only
Inventory Listings: Confirm with local inventory, global registration or use guidelines as applicable
