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MSDS for Stachydrine Hydrochloride

Identification

Product Name: Stachydrine Hydrochloride
Chemical Name: Proline, 1-carboxy-N,N,N-trimethyl-, hydrochloride
Synonyms: Betaine, L-Proline betaine hydrochloride, Stachydrinium chloride
CAS Number: 4136-37-2
Recommended Use: Laboratory reagent, research chemical, not for food or drug use
Manufacturer Details: Contact the supplier listed on the packaging or purchase invoice for specific company data
Emergency Phone: Refer to local poison control center or emergency contact listed with shipment

Hazard Identification

GHS Classification: Acute toxicity (oral) Category 5, Eye irritation Category 2B
Hazard Statements: May cause mild skin and eye irritation, dust inhalation aggravates respiratory symptoms
Signal Word: Warning
Hazard Symbols: Exclamation mark
Precautionary Statements: Avoid breathing dust or fume, wash hands thoroughly after handling, use personal protective equipment as required, get medical attention for exposure

Composition / Information on Ingredients

Chemical Name: Stachydrine Hydrochloride
Chemical Formula: C7H13NO2·HCl
Molecular Weight: 179.65 g/mol
Concentration: ≥ 98% (by weight)
Impurities: Trace moisture possible, minor organic contaminants from synthesis

First Aid Measures

Inhalation: Move individual to fresh air, ease breathing, seek medical advice for coughing or persistent discomfort
Skin Contact: Rinse thoroughly with soap and water, remove contaminated clothing, seek medical guidance if skin reaction appears
Eye Contact: Flush eyes gently with plenty of water for several minutes, remove contact lenses if present, contact medical personnel if irritation persists
Ingestion: Rinse mouth with water, never induce vomiting unless directed by a healthcare provider, seek medical assistance for large amounts or if unwell
Most Important Symptoms: Eye stinging, mild gastrointestinal upset, dry throat if inhaled

Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, dry chemical, foam, or carbon dioxide
Unsuitable Media: Do not use high-pressure streams as dust can become airborne
Hazards from Combustion: Main products include carbon dioxide, carbon monoxide, nitrogen oxides, hydrogen chloride gas
Protective Equipment for Firefighters: Firefighters require self-contained breathing apparatus and protective gear
Special Precautions: Fire can release irritating or toxic gases, keep away from heat or open flames

Accidental Release Measures

Personal Precautions: Wear laboratory gloves, goggles, lab coat, limit exposure and ensure adequate ventilation
Spill Clean-Up: Sweep up gently to minimize dust, place material in a sealed container, clean contaminated surfaces with water, avoid discharging to drains
Environmental Precautions: Collect spilled product to prevent it entering waterways, shield spills from storm drains, notify authorities if large releases threaten public water

Handling and Storage

Handling: Use only in a chemical fume hood or well-ventilated area, avoid generating dust, avoid contact with skin, eyes, and clothing, wear personal protective equipment
Storage: Store in a tightly closed container, keep in a cool, dry, and well-ventilated location, segregate from strong bases, oxidizing agents, and direct sunlight
Incompatibles: Strong oxidizers, strong acids, avoid sources of ignition, prevent contamination with moisture

Exposure Controls and Personal Protection

Engineering Controls: Use enclosures, local exhaust ventilation, or process isolation
Personal Protective Equipment: Safety goggles, laboratory gloves (nitrile or latex), lab coat or chemical-resistant apron, dust mask or respirator if powder handling
Hygiene Measures: Wash hands before eating, drinking, or leaving the laboratory, do not eat or drink near the chemical, handle according to appropriate laboratory safety guidelines
Occupational Exposure Limits: No established OSHA, ACGIH, or NIOSH exposure limits for stachydrine hydrochloride; minimize user exposure under routine handling

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Practically odorless
Odor Threshold: Not available
pH (10% solution): Ranges from 4.0 to 7.0
Melting Point/Range: 225-230°C (decomposition)
Boiling Point: Not available (decomposes before boiling)
Solubility: Freely soluble in water, sparingly soluble in ethanol, insoluble in non-polar solvents
Vapor Pressure: Not applicable under normal conditions
Flash Point: Not flammable under typical handling
Density: Approximately 1.32 g/cm³
Partition Coefficient: Not determined
Viscosity: Not available

Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Thermal Decomposition: May emit toxic fumes if heated above 200°C
Reactivity: Avoid contact with strong oxidizing agents, strong acids
Hazardous Reactions: Will not polymerize under normal circumstances
Conditions to Avoid: Excessive heat, open flame, direct sunlight, moisture exposure
Decomposition Products: Carbon monoxide, carbon dioxide, hydrogen chloride, nitrogen oxides

Toxicological Information

Acute Toxicity: Low acute oral toxicity (rat LD50 > 2000mg/kg), may cause mild nausea or irritation
Skin Corrosion/Irritation: Non-irritant or minor irritant; skin contact may cause slight dryness or reddening
Eye Damage/Irritation: May cause mild, reversible eye discomfort; rinsing usually relieves symptoms quickly
Respiratory Sensitization: Inhalation of powder may irritate airways, coughing, sneezing
Carcinogenicity: No ingredients classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity/Teratogenicity: No studies on mutagenic or reproductive effects available
Chronic Exposure: No evidence of organ toxicity or chronic health effects through workplace exposure

Ecological Information

Ecotoxicity: No detailed data on aquatic organisms; low expected hazard based on chemical nature
Mobility in Soil: Freely soluble in water, possibility of movement through soil to groundwater
Persistence/Degradability: Likely biodegradable in environmental conditions over time
Bioaccumulation: Not expected to significantly bioaccumulate
Other Adverse Effects: Do not release to environment without proper treatment, keep out of natural water bodies

Disposal Considerations

Waste Disposal: Gather any residue or contaminated materials, place in sealed waste container
Methods of Disposal: Incinerate in approved chemical waste facility; follow state, local, and federal regulations
Contaminated Packaging: Rinse empty containers, dispose in accordance with chemical container disposal law
Special Precautions: Never allow large quantities to enter water systems; coordinate disposal through licensed chemical waste handler

Transport Information

UN Number: Not regulated as hazardous material
Transport Hazard Class: Not classified as dangerous goods
Packing Group: Not assigned, non-hazardous
Environmental Hazards: None under standard transportation
Special Precautions: Keep material tightly sealed, dry, protect against extreme temperature swings; label outer packaging clearly when shipping in bulk

Regulatory Information

OSHA Status: Not regulated as hazardous by OSHA Standard (29 CFR 1910.1200)
TSCA Status: Listed or complies with TSCA inventory requirements
SARA Title III Section 313: Not designated as a reportable chemical
California Proposition 65: Not listed as a chemical known to cause cancer, birth defects, or reproductive toxicity
REACH (Europe): No registration required for research quantities, not a controlled substance
Other State/Local Laws: Comply with physical and health hazards reporting, prevent nonessential public exposure
WHMIS Canada: Considered non-hazardous, no classification assigned