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Material Safety Data Sheet: Sodium Taurocholate

Identification

Product Name: Sodium Taurocholate
Chemical Formula: C26H44NNaO7S
Other Names: Sodium taurocholate hydrate, Bile acid sodium salt
CAS Number: 145-42-6
Recommended Use: Laboratory reagent, biochemical research, pharmaceutical applications
Manufacturer/Supplier: Details available from packaging or supply documentation
Contact Information: Emergency contact listed on supplier label, with 24-hour access for chemical emergencies
Synonyms: Taurocholic acid sodium salt, Taurocholate sodium, Sodium taurocholate hydrate
UN Number: Not assigned

Hazard Identification

GHS Classification: Not classified as hazardous under GHS
Hazard Statements: May cause mild irritation to skin, eyes, or respiratory tract
Signal Word: None
Pictogram: None required
Precautionary Statements: Avoid inhalation of dust, contact with eyes and prolonged skin exposure; use adequate ventilation
NFPA Ratings: Health: 1, Flammability: 0, Reactivity: 0
PPE Recommendations: Basic lab safety clothing and equipment
Key Hazards: Dust formation, potential mild irritant

Composition / Information on Ingredients

Chemical Name: Sodium Taurocholate
Concentration: >99% (pure compound, as provided by most laboratory suppliers)
Impurities: Water of hydration may be present; check batch analysis
Molecular Weight: 537.7 g/mol
EC Number: 205-647-9
Ingredient Classification: Not classified as hazardous
Form: Solid powder or crystalline
Odor: Odorless or slightly musty

First Aid Measures

General Information: Move exposed person from area if necessary; seek medical attention for symptoms
Inhalation: Remove to fresh air; support breathing if needed; seek medical care if breathing becomes difficult
Eye Contact: Rinse thoroughly with water for at least 15 minutes, keeping eyelids open; seek medical attention if irritation persists
Skin Contact: Wash with plenty of soap and water; remove contaminated clothing and wash before reuse
Ingestion: Rinse mouth with water; do not induce vomiting; seek medical advice if feeling unwell
Symptoms to Watch For: Mild irritation, redness, coughing, sneezing, or shortness of breath

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, water spray, or standard foam
Unsuitable Media: High-pressure water jets might spread the product
Specific Hazards: Product is not flammable; decomposition at high temperatures may produce hazardous fumes such as carbon oxides, sulfur oxides, sodium oxides, nitrogen oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing
Special Precautions: Avoid inhalation of combustion products; ventilate area after extinguishing
Thermal Decomposition: Toxic and irritating vapors possible if burned

Accidental Release Measures

Personal Precautions: Wear recommended personal protective equipment; avoid generating dusty conditions; avoid contact with eyes, skin, and clothing
Environmental Precautions: Prevent material from entering waterways or drainage systems
Methods for Cleaning Up: Sweep up spilled material with minimal dust generation; collect in suitable container for disposal; wash spill site after material pick-up is completed
Decontamination: Clean surfaces with plenty of water; ventilate area
Disposal: Follow disposal regulations for non-hazardous laboratory waste

Handling and Storage

Handling: Avoid dust formation and inhalation; use in well-ventilated spaces; handle with care to prevent release into environment
Hygiene Practices: Do not eat, drink, or smoke when handling; wash hands after use
Storage Conditions: Store in cool, dry location; keep containers tightly closed; protect from light, moisture, and incompatible substances (strong oxidizing agents)
Specific Storage Requirements: Segregate from feed, foodstuffs, strong acids and bases
Packaging Materials: Store in original containers or chemical-resistant sealed containers
Incompatible Materials: Strong oxidizers, strong acids and bases

Exposure Controls and Personal Protection

Exposure Limits: No occupational exposure limit established
Engineering Controls: Use adequate ventilation or local exhaust to minimize dust concentrations
Personal Protective Equipment: Lab coat, chemical resistant gloves, safety goggles
Respiratory Protection: Use dust mask or respirator if airborne powder is present
Skin Protection: Wear gloves; use barrier creams for extra precaution
Eye Protection: Chemical splash goggles or face shield
Hygiene: Wash hands thoroughly after handling; avoid touching face and eyes

Physical and Chemical Properties

Appearance: White or off-white, crystalline powder
Odor: Odorless or slight musty odor
pH (5% Solution): 7–9
Melting Point: Decomposes before melting; reported above 260 °C
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water, slightly soluble in ethanol
Vapor Pressure: Not applicable
Density: Approximately 1.36 g/cm³
Partition Coefficient (log Kow): Not available
Evaporation Rate: Not applicable
Flash Point: Not applicable
Autoignition Temperature: Not applicable
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable at room temperature in sealed container under normal storage and handling conditions
Possibility of Hazardous Reactions: None expected under standard use
Conditions to Avoid: Moisture, excessive heat, light
Incompatible Materials: Strong oxidizing agents, strong acids and bases
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides, sodium compounds
Reactivity: Does not react vigorously with common substances under ambient conditions

Toxicological Information

Acute Toxicity: Limited data on human toxicity; LD50 (oral, rat): >5000 mg/kg (low toxicity)
Routes of Exposure: Inhalation, skin, ingestion, eyes
Potential Health Effects: Possible mild irritation to respiratory tract, eyes, skin; ingestion may cause gastrointestinal upset
Symptoms: Coughing, sneezing, eye watering, mild transient redness
Chronic Effects: No evidence of long-term health risk at standard laboratory exposure
Carcinogenicity: No data indicating carcinogenic effects
Mutagenicity: No data reported
Reproductive Toxicity: No data indicating reproductive risk
Sensitization: Not known to cause allergic reactions

Ecological Information

Ecotoxicity: No acute data available; low hazard expected based on chemical structure
Persistence and Degradability: Expected to be biodegradable; breakdown occurs through hydrolysis and microbial action
Bioaccumulation Potential: Low, due to solubility and nature of chemical
Mobility in Soil: May leach into groundwater; product is water soluble
Other Adverse Effects: No significant ecological concern at small, lab-scale release; avoid large uncontrolled discharges to water bodies
Aquatic Toxicity: No data available, but unlikely to be acutely toxic at realistic concentrations

Disposal Considerations

Product Disposal: Collect solid material in clearly labeled containers for disposal according to local, regional, and national regulations; avoid discharge into drains
Contaminated Packaging: Rinse thoroughly before disposal; follow local guidelines for chemical containers
Waste Codes: Not listed as hazardous waste; classification should be confirmed with local authorities
Methods of Disposal: Chemical waste incineration or landfill permitted for non-hazardous material
Precautions: Wear suitable PPE during disposal; prevent material from entering water systems

Transport Information

UN Number: Not assigned
ADR/RID: Not regulated
IMDG: Not regulated
IATA: Not regulated
TDG: Not regulated
Proper Shipping Name: Sodium Taurocholate or “chemical, N.O.S.” (laboratory shipment)
Packaging Group: Not applicable
Environmental Hazards: No
Special Precautions for Transport: Prevent spillage; use secure, labeled containers

Regulatory Information

Inventory Status: Listed in TSCA, EINECS/ELINCS (EU), DSL (Canada), other major inventories
GHS Labelling: Not hazardous, precautionary language only
Right-to-Know: Not listed as hazardous in US or EU hazard inventories
REACH Status (EU): Not registered for industrial-scale production or widespread consumer use
Labelling Requirements: Standard chemical labeling for laboratory materials; workplace safety documentation required
Other Regulations: Avoid environmental release; ensure proper downstream notification of hazards