© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Sodium Sulfamethoxazole
Synonyms: Sulfamethoxazole sodium salt
Chemical Formula: C10H10N3NaO3S
CAS Number: 6829-86-3
Recommended Use: Pharmaceutical intermediate, antibacterial agent
Manufacturer Information: Company name, address, phone number for emergencies
Emergency Contact: Local poison control, national chemical emergency number
Relevant Uses Advised Against: Non-medical applications
GHS Classification: Acute toxicity (oral), Eye irritation, Skin sensitization
Signal Word: Warning
Hazard Statements: Harmful if swallowed, Causes eye irritation, May cause allergic skin reactions
Pictograms: Exclamation mark
Precautionary Statements: Avoid inhalation, avoid contact with skin and eyes, wash thoroughly after handling, wear protective gloves and eye protection
Routes of Exposure: Inhalation, ingestion, skin, eyes
Potential Health Effects: Allergic reactions, gastrointestinal upset, rash, liver or kidney effects in sensitive individuals
Target Organs: Skin, eyes, liver, kidneys
Chemical Name: Sodium Sulfamethoxazole
Concentration: 98–100%
Impurities: Trace process-related materials
EC Number: 229-971-9
Molecular Weight: 287.26 g/mol
Inhalation: Move person to fresh air, provide oxygen if breathing is difficult, seek medical attention for persistent symptoms
Skin Contact: Remove contaminated clothing, wash exposed skin with plenty of soap and water, seek medical attention for rash or irritation
Eye Contact: Rinse with plenty of water for at least 15 minutes, lift eyelids occasionally, remove contact lenses if present and easy to do, seek medical attention
Ingestion: Rinse mouth with water, do not induce vomiting unless directed by medical personnel, seek immediate medical help
Most Important Symptoms and Effects: Allergic reactions, skin and eye irritation, gastrointestinal discomfort, possible delayed effects on liver and kidneys
Note to Physicians: Treat symptomatically, monitor for severe allergic or toxic reactions, especially in patients with compromised renal or hepatic function
Suitable Extinguishing Media: Water spray, dry chemical, carbon dioxide, foam
Unsuitable Extinguishing Media: High-velocity water jets
Specific Hazards: May produce hazardous fumes under fire conditions, including oxides of nitrogen and sulfur
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective clothing
Special Fire-Fighting Procedures: Stay upwind, avoid inhalation of fumes, cool containers exposed to flames with water spray, prevent runoff from reaching sewers or waterways
Personal Precautions: Evacuate non-essential personnel, use appropriate protective equipment including gloves, eye and respiratory protection
Environmental Precautions: Prevent further leakage or spillage if safe to do so, avoid discharge into drains or surface water
Methods for Cleaning Up: Sweep up spilled material, avoid generating dust, transfer to suitable closed containers for disposal, ventilate area and wash spill site after material pickup is complete
Handling: Use engineering controls to minimize dust formation, handle using appropriate PPE, avoid contact with eyes, skin, clothing, avoid inhalation of dust
Hygiene Practices: Wash hands thoroughly after handling, remove contaminated clothing and wash before reuse, do not eat or drink while handling
Storage Conditions: Store in tightly closed containers, keep in a cool, dry, well-ventilated area away from incompatible substances like strong acids and oxidizers, protect from moisture and direct sunlight
Incompatible Materials: Strong acids, strong oxidizing agents
Specific End Uses: For use in laboratory, research, or pharmaceutical manufacturing settings
Occupational Exposure Limits: No specific limit established, handle as nuisance dust
Engineering Controls: Local exhaust ventilation, fume hood, process enclosures
Personal Protective Equipment:
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 9–11 (1% solution in water)
Melting Point / Freezing Point: Decomposes before melting
Initial Boiling Point / Boiling Range: Not available
Flash Point: Not applicable
Evaporation Rate: Not available
Flammability: Non-flammable
Upper/Lower Flammability or Explosive Limits: Not applicable
Vapor Pressure: Negligible at ambient conditions
Vapor Density: Not available
Solubility: Freely soluble in water, slightly soluble in alcohol
Partition Coefficient (n-octanol/water): Not determined
Auto-ignition Temperature: No data
Decomposition Temperature: > 200 °C
Viscosity: Not applicable
Chemical Stability: Stable under normal conditions of use and storage
Possibility of Hazardous Reactions: Not expected under prescribed use
Conditions to Avoid: High temperatures, exposure to moisture, humidity, direct sunlight
Incompatible Materials: Strong acids, oxidizing agents
Hazardous Decomposition Products: Toxic gases such as nitrogen oxides and sulfur oxides may form under fire or decomposition
Acute Toxicity: Harmful if swallowed (rat oral LD50: 2500 mg/kg)
Skin Corrosion/Irritation: Can irritate skin; may cause rashes or dermatitis with repeat exposure
Serious Eye Damage/Irritation: May cause severe eye irritation and pain
Respiratory or Skin Sensitization: Potential for allergic skin reactions, asthma-like symptoms
Germ Cell Mutagenicity: Not classified as mutagenic based on current data
Carcinogenicity: Not listed by IARC, NTP, or OSHA as a carcinogen
Reproductive Toxicity: Evidence of reproductive effects at high doses in animal studies
STOT (Specific Target Organ Toxicity): May affect kidneys and liver with prolonged or repeated exposure
Symptoms Related to Exposure: Allergic reactions, nausea, vomiting, headache, dizziness
Delayed and Immediate Effects: Hypersensitivity reactions, hematological effects in susceptible people, possible delayed onset of symptoms
Ecotoxicity: Harmful to aquatic life, especially algae and invertebrates
Persistence and Degradability: Moderately persistent, partial degradation through photolysis and biodegradation
Bioaccumulative Potential: Low to moderate (log Kow estimated below 2)
Mobility in Soil: Mobile in water, risk of leaching to groundwater
Other Adverse Effects: Pharmaceuticals in surface waters can affect microbial communities
Waste Treatment Methods: Incinerate or dispose of as hazardous pharmaceutical waste in accordance with local, regional and national regulations
Contaminated Packaging: Dispose of empty containers as hazardous waste; do not reuse
Sewage Disposal: Do not release into sewers or the environment
Additional Precautions: Avoid all unnecessary exposure during disposal procedures
UN Number: Not regulated for transport
Proper Shipping Name: Not classified as a dangerous good under transport regulations
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Special Precautions for Transport: Protect from excessive heat and physical damage
Environmental Hazards: No strong evidence for environmental hazard during transport, but avoid accidental spills
OSHA Status: Not classified as hazardous under OSHA Hazard Communication Standard
EPA Status: Not on the list of regulated substances, but general pharmaceutical controls apply
TSCA: Listed
DSL/NDSL (Canada): Listed
REACH (EU): Registered
Labeling Requirements: Labels indicating GHS hazard and precautionary statements
Other Regulations: Conform with state, federal, and local regulations for storage, handling, disposal and reporting of hazardous spills
Workplace Hazard Categories: Sensitizer, Irritant, Harmful if swallowed
