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Sodium Ferulate: A Natural Compound with Modern Applications

Historical Development

Discovery of sodium ferulate traces back to decades of research on traditional Chinese medicine, where ferulic acid appeared in rhizomes like Angelica sinensis and Ligusticum chuanxiong. For generations, these plants served as cornerstones in herbal therapies for blood circulation and inflammation. Scientists eventually isolated ferulic acid and converted it to sodium ferulate to boost both solubility and bioavailability. Hospitals in China incorporated sodium ferulate injections and tablets into mainstream treatment by the end of the twentieth century, mainly for cardiovascular and cerebrovascular disorders. Extraction methods started by soaking plant material in ethanol, filtering it, and then crystallizing it with sodium bicarbonate. Over years, refinements increased yields and purity, helping bridge folk knowledge and pharmaceutical regulation. Each advancement brought natural medicines closer to widely accessible and standardized drug products.

Product Overview

Sodium ferulate hits the market most often as a white or slightly yellow crystalline powder. Most users encounter it in injectable vials, tablets, or capsules packaged in moisture-proof containers. The product’s main draw comes from antioxidant and anti-inflammatory properties, rooted in the stability of the ferulic acid backbone and the improved water compatibility from the sodium salt. Health care professionals in Asia prescribe it widely for disorders linked to oxidative stress, such as stroke, thrombosis, and diabetic complications. A smaller but growing audience seeks sodium ferulate in nutraceuticals and adjunct therapies in Europe and North America, pinning hope on its botanical roots and safety track record. Unlike newer synthetic drugs, this product tells a story that blends cultural heritage with modern science.

Physical & Chemical Properties

Sodium ferulate powder flows freely when dry, offering a neutral to slightly bitter taste. Solubility in water reaches about 10 mg per mL at room temperature, which supports its use in IV formulations and pills. Chemical analysis reveals a molecular formula of C10H9NaO4 with a molecular weight near 216.16 g/mol. The carboxyl group reacts with sodium to form the salt, which results in greater hydrophilicity compared with the parent acid. The compound melts above 200°C, keeping its structure stable through standard sterilization methods. Under routine light and air, sodium ferulate holds up for months, but humidity or repeated heating speed up degradation, leading manufacturers to use desiccants and protective packaging. Smell profiles register almost nothing, a big plus for patient compliance.

Technical Specifications & Labeling

Quality control guidelines stretch beyond basic purity, demanding less than 0.1% impurities in pharmaceutical-grade sodium ferulate. Product sheets specify 98–102% sodium ferulate content by weight, along with acceptable levels of moisture, heavy metals, and microbial contamination. Labels clearly state not only the compound’s chemical name but dosage instructions, storage recommendations (cool, dry, dark), and batch details. Larger suppliers include certificates of analysis outlining particle size, assay results (usually by HPLC), and safety testing. Labels on injections outline sterility validation, pyrogen-free status, and compatibility data for IV mixing – measures set by both Chinese and international pharmacopeias. Marketers have to remain vigilant about regulatory changes, as even small batch inconsistencies can trigger recalls or batch quarantines, underscoring tight global oversight.

Preparation Method

Most extraction begins with plant material, ground up and soaked in ethanol or methanol to liberate ferulic acid and related phenolic acids. The solution passes through filtration before acidification, which forces ferulic acid out of solution. After collection through centrifugation or simple sedimentation, the solid gets washed, then neutralized with sodium hydroxide or sodium bicarbonate, forming sodium ferulate. This product gets crystallized again from water or ethanol. Each purification brings down residual plant oils and pigments, with repeated recrystallization pushing purity higher. To scale up, producers use stainless steel reactors, automate solvent recovery, and rely on mechanical filtration to handle industrial quantities. Waste management for organics and heavy metals shapes each facility’s environmental footprint. In smaller labs, students can produce sodium ferulate with just glassware and common reagents, making it a favorite for early synthetic training.

Chemical Reactions & Modifications

Sodium ferulate enters several straightforward chemical transformations. The phenolic hydroxyl group makes it a target for methylation, often yielding derivatives like methyl ferulate, which researchers chase for altered pharmacokinetics or improved stabilization. Cross-linking through its unsaturated side chain produces dimers or polymers, explored as antioxidant agents in food packaging or biodegradable plastics. Oxidation reactions break down the ferulate backbone, a topic with environmental import for tracking drug breakdown in waste streams. Some research teams graft sodium ferulate onto nanoparticles or biopolymers to boost its delivery to specific tissues or prolong circulating half-life. Its simple carboxylic acid and aromatic ring allow creative chemical engineering, often with routine reagents like alkyl halides or oxidizing agents. Side products from these reactions guide analysts in trace impurity detection, bringing analytical chemistry full circle to product safety.

Synonyms & Product Names

Pharmacies and suppliers trade sodium ferulate under names like Sodium 4-Hydroxy-3-methoxycinnamate, Sodium ferulic acid, and Chinese equivalents such as Na-Ferulate and Suan Liu Suan Na. Branded pharmaceutical products carry names tied to manufacturers, helping clinicians identify generics or alternatives. The synonyms matter for regulatory and import-export documentation, where chemical abstracts numbers (CAS) – 24276-84-4 for sodium ferulate – play a role. Some suppliers include the Chinese Pharmacopeia coding or international harmonized system codes for bulk export. Trade name confusion sometimes triggers customs delays or prescription mixups, prompting more unified naming and translation practices. Health professionals keep a list of synonyms handy to ensure patients and procurement teams access the right formulation regardless of brand or supplier.

Safety & Operational Standards

Production facilities set rigorous environmental and occupational safety procedures. Workers must wear gloves, goggles, and long sleeves to handle solvents, acids, and bases during extraction and crystallization. Ventilation protects them from solvent fumes and dust, while emergency showers and eyewash stations provide first aid for accidental splashes. Finished products pass sterility and pyrogen testing, especially for injectables bound for hospital pharmacies. Shelf-life stability studies shape guidelines for storage temperature and humidity, minimizing spoilage and breakdown. National and international regulatory agencies – China’s NMPA, US FDA, or EU EMA – send inspectors to verify GMP compliance and reported safety data. Adverse reactions or contamination triggers alerts, batch withdrawals, and public reports. The drive for standardized procedures, lot traceability, and professional training threads through every phase of the product’s journey from lab to hospital cart.

Application Area

Sodium ferulate reaches far beyond cardiac care wards. Doctors in neurology turn to IV injections for cerebral infarction and post-stroke rehabilitation, citing research that points to blood thinning and vessel relaxation effects. Diabetes clinics apply it to protect renal microcirculation in nephropathy, where oxidative stress threatens fragile capillaries. Eye doctors investigate benefits in preventing retinopathy and glaucoma progression by improving blood flow to ocular tissues. In rheumatology, patients with arthritis explore sodium ferulate for swelling and pain relief, aiming to reduce steroid doses. Some athletes and health-conscious consumers add it to supplement stacks to bolster antioxidant defenses, betting on decades of botanical use to back safety claims. Animal health researchers experiment with livestock feed additives, hoping to support cardiovascular or metabolic health in intensive farming operations. These application zones flow from both traditional evidence and new laboratory data, rewarding the compound’s unique blend of heritage and innovation.

Research & Development

Corporate and academic scientists push sodium ferulate into new dosing models, delivery mechanisms, and chemical analogues. Nanoparticle carriers, liposomal encapsulation, and sustained-release coatings dominate research, each promising smoother blood levels and fewer side effects. Structural modifications attempt to target tissues like the heart, kidneys, or brain selectively, hunting greater benefit at lower doses. Clinicians advocate for more rigorous double-blind trials, pitching for broader indication approval in the West. Research teams compare sodium ferulate to aspirin, clopidogrel, or statins, seeking either new therapeutic windows or adjunct routines that minimize pharmaceutical load. Digital modeling platforms screen libraries of ferulate derivatives, predicting anti-inflammatory or anti-cancer properties based on molecular fingerprints. International consortia chase grants and translational funding, seeing a future where sodium ferulate stands shoulder-to-shoulder with synthetic drugs in standard guidelines. Throughout these projects, compliance with Good Laboratory Practices (GLP) and ethical review boards takes center stage, reminding all players that botanical origins must measure up to twenty-first-century scrutiny.

Toxicity Research

Toxicologists track both acute and chronic exposure, focusing on organ health, reproductive toxicity, and mutagenic effects. Rodent studies set no-observed-adverse-effect levels well above routine therapeutic doses, with oral and IV formulations showing minimal adverse events. Isolated reports list gastrointestinal discomfort and, rarely, hypersensitivity rashes, especially in people sensitive to phenolic compounds. Reproductive outcome studies on pregnant lab animals show no teratogenicity at typical exposure. Chronic high-dose intake rarely elevates liver enzymes or damages renal function, but regulators urge caution in people with underlying hepatic or renal failure. Animal modeling supports safety, but controlled, longitudinal human studies remain thin. Pharmacovigilance databases record no mass safety issues even after millions of patient exposures in China, offering reassurance to cautious clinicians and family members alike. Vigilance grows as the compound moves into supplements and new patient groups, with researchers advocating for mandatory reporting, better adverse-event databases, and wider consumer education.

Future Prospects

Growth in sodium ferulate’s global reach rests on blending its traditional medicine story with rigorous clinical evidence. Demand for plant-based, low-toxicity drugs fills hospitals and health food aisles. Chinese regulatory and clinical bodies continue to set the pace with large patient datasets, while Western researchers build trials for regulatory submission. Collaborations with chemists explore not just pharmaceutical but agro-industrial and environmental uses for sodium ferulate and its derivatives. The potential for expanded use in chronic disease management, especially in aging populations, attracts public and private funding. Advances in synthetic biology promise bioengineered ferulic acid sources that bypass traditional agriculture, broadening supply and reducing environmental impact. If clinical research confirms new applications – perhaps in neurodegenerative or autoimmune disease – a new generation of botanically inspired drugs could follow. Success relies on honest discussion of limitations, open data sharing, and transparency at every level, from laboratory bench to bedside.




What is Sodium Ferulate and how is it naturally extracted?

Getting to Know Sodium Ferulate

Sodium ferulate has been around in herbal medicine circles for quite a while. People often cross paths with it thanks to its roots in Chinese medicine. This compound, coming from ferulic acid, gets its fame from its anti-inflammatory and antioxidant properties. Scientists noticed its potential, so it moved beyond tradition and found a slot in research labs and even as an ingredient in supplements and some treatments.

Natural Extraction Methods

The journey often starts in fields of Angelica sinensis, or Dong Quai. Others look to rice bran and wheat bran as rich sources. Ferulic acid is locked into the cell walls of these plants. The main challenge isn’t about discovering where it hides—it’s about coaxing it into a form the body can use.

Traditional extraction uses ethanol or water to draw out the ferulic acid. The process combines grinding the plant material with these liquids, heating and stirring it for several hours. What’s left gets filtered. The result is a solution filled with ferulic acid. The next task: mixing in sodium hydroxide to convert it into sodium ferulate. After removing all the unwanted bits with more filtration and washing, and letting it dry out, what remains is the desired compound. This isn’t just an academic exercise. The method preserves the structure of ferulic acid, keeping its protective qualities intact for use in tablets, powders, and even intravenous drips for hospital use in some countries. The push to use less toxic solvents and greener methods has led some innovators to try enzymatic extraction, making the whole process safer and friendlier to the environment. This works by breaking the tough plant cell walls using enzymes instead of harsh chemicals. The focus on sustainable production responds to both environmental concerns and consumer demand for cleaner, safer ingredients.

Why Sodium Ferulate Has Caught Attention

Interest in sodium ferulate extends beyond its chemistry. Researchers keep highlighting its anti-clotting and anti-inflammatory actions. Patients in China use it for vascular health, especially those dealing with high blood pressure and heart complications. The National Center for Biotechnology Information (NCBI) publishes studies showing it blocks harmful free radicals and calms inflammation at the cellular level. With evidence stacking up, people have begun to see it as more than just another plant extract. Instead, it’s a bridge between ancient remedies and modern medical science.

Looking at the Broader Picture

The safety and purity of sodium ferulate matter a lot, since it often ends up in medicine or food products. Adulterated or impure material can lead to health risks, especially when large scale factories cut corners to speed up the process. Trusted brands stick with standardized testing and certification, ensuring what reaches pharmacies and supplement shelves is what the label promises.

Moving to greener extraction isn’t just a trend for the marketing team. It has real effects on the land and the people working with these crops. Synthetic solvents and harsh conditions can leave unhealthy residues in waste water and in our food. Better methods cut down on pollution, use less energy, and often result in a cleaner, more effective product. The science keeps evolving. New research may soon push the field further, creating better ways to unlock the benefits of plants without sacrificing safety or the natural world around us.

What are the main health benefits of Sodium Ferulate?

Understanding Sodium Ferulate

Sodium ferulate crops up in conversations about plant-based remedies, especially in East Asian medicine cabinets. It springs from ferulic acid, found in grains like rice and wheat. Over time, it’s earned a spot in supplement bottles because folks noticed it seemed to help beyond the pages of folk remedies. Many might see it as just another supplement in the health aisle, but the research paints a more interesting picture.

Taming Inflammation

Chronic inflammation ranks among the top underlying troubles leading to heart disease, diabetes, and arthritis. Sodium ferulate works as a natural inflammation reliever. Science journals highlight this. A study published in European Journal of Pharmacology saw that the compound can calm the body’s inflammatory response. I’ve talked with health professionals who notice how targeting inflammation at its root helps patients feel better before big issues show up. By making inflammatory molecules back down, sodium ferulate lets the body heal faster and bounce back stronger.

Shielding the Heart

Everyone has a friend or family member tracking cholesterol or worrying about their next blood pressure reading. Sodium ferulate has been studied for its knack for improving blood flow and protecting blood vessel walls. Researchers believe it decreases stickiness in platelets, making blood less likely to clot dangerously. The Journal of Ethnopharmacology shared work suggesting people using sodium ferulate saw lower risks of thrombotic events. As someone with a family history of heart trouble, keeping vessel walls healthy can’t be overlooked.

Fighting Oxidative Stress

Antioxidants don’t just make headlines; they’re crucial. Our bodies face constant battering from pollutants, UV rays, and stress. Sodium ferulate stands out as a strong antioxidant. Studies at Chinese medical universities showed it scavenges free radicals better than some popular vitamins. Fewer free radicals mean cells last longer, skin keeps its glow, and the brain works smoother into older age. After seeing friends struggle with memory loss in their parents, any edge in cellular defense makes a difference.

Supporting Brain Function

Scientists pursue treatments for memory decline and neurodegenerative diseases harder every year. Public nutrition forums increasingly mention sodium ferulate. It appears to help guard brain cells against degeneration by reducing harmful protein buildup. Animal studies report fewer tangled proteins in the brain, similar to what’s found in Alzheimer’s disease. Close relatives of mine living with cognitive changes often grasp for any hope to keep their independence longer. Introducing a supplement with real backing from neuroscience offers a path to slower decline.

Room for Caution and Where to Next

Like most supplements, sodium ferulate needs smart use. Research up to 2024 points to safety at commonly recommended doses, but that doesn’t mean every bottle is the same. People on blood thinners or under treatment for cancer should talk to doctors first. Some doctors wish for larger clinical trials. Still, early findings push for broader research, especially to see how sodium ferulate interacts with modern medicines. Better regulation of supplement purity and more funding for human studies would go a long way for consumers and clinicians alike.

Practical Tips

For people exploring sodium ferulate, starting slow and logging any changes matters. Pharmacies in China routinely stock it for heart or joint support, but folks picking it up elsewhere should stick with trusted brands and check for certification. Healthcare providers encourage this kind of cautious optimism—open to possibilities, but grounded in both tradition and emerging science.

Is Sodium Ferulate safe for daily consumption?

Diving into Sodium Ferulate

Sodium ferulate gets a lot of attention in wellness circles, especially since it's found naturally in some plants and often shows up in supplements. This compound, a derivative of ferulic acid, has a resume filled with antioxidant potential, and people in some parts of Asia have used it to support heart health and even circulation. Most folks aren’t grabbing sodium ferulate from the grocery store; they usually see it in pill form or as part of traditional remedies.

Sifting Through Science and Tradition

Scientists have looked into sodium ferulate for its antioxidant and anti-inflammatory effects. Several studies out of China show the compound might help protect blood vessels, ease certain symptoms tied to high cholesterol, and even show benefits for brain health. Researchers have even tested it as an add-on treatment in some chronic illnesses. In these studies, usual doses of sodium ferulate ranged from 100mg to a gram a day, and folks taking it daily rarely reported major problems.

Still, most of these studies clock in under a year. Side effects reported so far sound pretty mild—maybe a bit of digestive upset or dizziness now and then. To put it simply, nothing so far points to common dangerous effects in healthy people at typical amounts.

Regulation and Oversight

Here’s the thing. Sodium ferulate is not a household name in places like the United States, so the Food and Drug Administration hasn’t given it a gold star. Over in China, doctors can prescribe it, often for blood vessel support, so there’s some track record under formal supervision. Supplements found online or in shops might not follow strict rules, so labels don’t always match what’s inside. This can trip up anyone assuming each bottle means the same thing.

Risk Factors and Cautions

People with allergies to wheat or plant products might want to pause before adding sodium ferulate to their routine. Pregnant or breastfeeding folks get left out of most research, so it’s tough to say what’s safe for them. Anyone on blood thinners or meds for circulation needs to check with a professional, as sodium ferulate could boost blood flow and might add to the effects of other drugs.

Personal health always matters more than what a supplement promises on the label. Age, liver and kidney health, and any chronic conditions matter when it comes to safety. That’s true for sodium ferulate, too.

Where to Go From Here?

Supplements carry a certain appeal. They promise an edge, sometimes backed by centuries of folk use, sometimes by a splashy new study. For sodium ferulate to fit into daily life with real confidence, larger studies outside of Asia could help, with better reporting on long-term effects. Regulatory agencies should tighten manufacturing standards so each bottle lists what’s really inside. Health professionals can help by guiding their patients, checking for interactions, and keeping tabs on research as it comes out.

Those looking to add sodium ferulate for daily health might want to slow down and ask questions. Check in with a healthcare provider, especially if you have health conditions or take regular meds. No pill fits every person, especially when science is still catching up. Caution, not hype, offers the best foundation for real wellness decisions.

What are the typical applications of Sodium Ferulate in supplements or food products?

The Drive Behind Using Sodium Ferulate

Sodium ferulate comes from ferulic acid, a compound that exists naturally in grains like rice bran and wheat. Over time, researchers noticed its strong antioxidant power. That’s a big deal. Oxidative stress stirs up all sorts of trouble inside the body—think about how rust damages metal. Oxidation does something similar to our cells. Antioxidants help slow this wear and tear. Because of this, experts started including sodium ferulate in supplements, hoping to support the body’s defense systems.

Common Ways Sodium Ferulate Shows Up in Supplements

Look at the shelves in health stores, especially brands that focus on heart or liver health. Plenty of them contain sodium ferulate alongside other herbal ingredients. People often choose these products to help with blood circulation. Years back, I met a nutritionist who recommended sodium ferulate tablets for her patients with “thick blood,” saying it could help to keep their vessels smooth.

Older folks in China have used supplements with sodium ferulate for decades. It isn’t just hype—a study published in Phytotherapy Research found benefits for folks with heart and vascular problems. So it’s no surprise that companies still pack sodium ferulate into compounds marketed for heart wellness. Sometimes, manufacturers blend it into multi-ingredient capsules aimed at liver protection, hoping to cut down on the impact of daily fat, sugar, or alcohol intake.

How It Finds Its Way Into Foods

Sodium ferulate sometimes pops up in functional foods, mostly for its antioxidant value. Think nutrition bars, drinks, or powdered mixes. The logic is pretty simple: people want to squeeze extra good stuff out of everyday snacks and drinks. Having read ingredient labels on many imported products, I noticed sodium ferulate in some fortified soy or oat beverages claiming to fight free radicals.

In cereal-based foods, manufacturers use sodium ferulate for more than just shelf-life extension. Yes, antioxidants help keep foods fresh longer, but companies also aim to offer perceived wellness benefits. In China, one brand markets rice noodles with sodium ferulate for older adults, promising “more vigor, less worry.” The examples pile up, and they all point to a steady trend: many brands want to give their foods an extra nutritional punch by adding antioxidants.

Safety and the Evidence Issue

Not every new supplement ingredient wins a gold star. Sodium ferulate stands on decent ground because it’s derived from plants people already eat. Still, a handful of clinical trials can’t give the full picture yet. Investigators have seen improved blood flow and reduced inflammation in some animal and small human studies. Yet, experts keep asking for more data before making bigger promises.

Regulators in China and some European countries cleared sodium ferulate for use in certain foods and supplements. The US hasn’t given the same nod, so shoppers won’t spot it in mainstream products here. Most of the research comes out of Chinese universities. Some studies point to possible interactions with blood thinners, so anyone thinking about supplements needs to talk to a doctor, especially if they have other medical conditions.

Better Transparency and Quality

Consumers often feel confused by long lists of strange-sounding ingredients. One way forward: companies should be more open about why they include sodium ferulate and what the science really says. Cutting back on misleading health claims and focusing on honest education would help people make more informed choices about what they put on their plates or take as pills.

Are there any side effects or interactions associated with Sodium Ferulate?

Why Sodium Ferulate Draws Attention

Many folks in China and other parts of Asia look to sodium ferulate for its herbal roots. Coming from ferulic acid in angelica sinensis, it has a reputation for fighting inflammation and thinning blood. People with heart disease, stroke risk, or memory troubles sometimes turn to it hoping for extra support. It’s easy to find over the counter in some countries, making it tempting to try without a doctor’s advice.

Possible Side Effects People Often Ignore

No medicine comes without baggage. Doctors have reported headaches, dizziness, and stomach upset with sodium ferulate. Some users develop rashes or skin itch, which means an allergy has kicked in. In more serious cases, blood pressure may drop and people feel faint. Nausea and dry mouth may also show up, especially when the stomach is empty.

A few studies and patient reports describe bruising and nosebleeds, especially for those already on blood thinners. This risk increases for anyone with liver concerns or people who bruise easily.

How Sodium Ferulate Mixes with Common Medications

Sodium ferulate thins the blood by slowing platelet clumping. It can boost the effects of aspirin, warfarin, clopidogrel, or other drugs that keep blood from clotting. Taking both together can mean unexpected bleeding, both inside and where you can see it. Folks on anti-inflammatory medication like ibuprofen or naproxen have also reported more stomach sensitivity and bleeding.

People using diabetes medicine may see changes in blood sugar control. Drug guides also mention possible trouble with liver enzymes, which concerns those on cholesterol pills, anti-epileptics, or some antifungals.

Not Everything Fits Every Person

Older adults with several health problems need to ask extra questions. A routine herbal supplement for one person creates risks for another, especially if there’s a kidney or liver issue. Kids and women who are pregnant or breastfeeding deserve extra caution. Not enough research covers these groups in detail, leaving doctors to play it safe and suggest other treatments.

Label quality and consistency vary by country and brand. Dose differences, hidden ingredients, or contaminants are not rare in the supplement market. With sodium ferulate, lack of consistent regulation sometimes leads to unexpected side effects caused by what’s in the bottle, not sodium ferulate itself.

Making Choice with Knowledge

No health decision should happen in secret. Healthcare professionals, pharmacists, and even some well-read nurses catch problems with herb-drug mishaps before they start. A person taking several medicines or blood thinners should be honest with the whole care team before starting sodium ferulate.

Safe use relies on asking the right questions, reading up on brand quality, and never making big changes without guidance. Reporting side effects and checking routine bloodwork gives the best shot at avoiding harm. Traditional medicines have their place, but staying healthy means putting facts over wishful thinking. Anyone thinking about sodium ferulate owes it to themselves to learn the risks, check for interactions, and respect their body’s signals.

Sodium Ferulate - Natural Extraction
Names
Preferred IUPAC name Sodium (E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enoate
Other names Ferulic acid sodium salt
Sodium ferulic acid
Sodium 4-hydroxy-3-methoxycinnamate
Pronunciation /ˈsəʊdiəm ˈfɛr.jə.leɪt/
Identifiers
CAS Number 538-23-8
3D model (JSmol) `3D model (JSmol)` string for **Sodium Ferulate - Natural Extraction**: ``` C1=CC(=CC=C1C=O)OCC2=CC=CC=C2C(=O)[O-].[Na+] ```
Beilstein Reference 1728233
ChEBI CHEBI:50274
ChEMBL CHEMBL203283
ChemSpider 151274
DrugBank DB13003
ECHA InfoCard 875aa3d4-9bdc-4ad4-9ad8-91ff7b23d460
EC Number 214-684-5
Gmelin Reference 87852
KEGG C00950
MeSH Sodium Ferulate"[MeSH]
PubChem CID 152166
RTECS number CV8060000
UNII YF1NJ3Q44X
UN number UN2811
Properties
Chemical formula C10H9NaO4
Molar mass 194.14 g/mol
Appearance White or off-white crystalline powder
Odor Odorless
Density 0.5 g/cm³
Solubility in water Soluble in water
log P -2.72
Acidity (pKa) 9.59
Basicity (pKb) 12.6
Magnetic susceptibility (χ) −24.0×10⁻⁶ cm³/mol
Refractive index (nD) 1.521
Viscosity Viscous liquid
Dipole moment 2.34 D
Thermochemistry
Std molar entropy (S⦵298) NaN
Pharmacology
ATC code B01AB12
Hazards
Main hazards Not hazardous under normal conditions of handling.
GHS labelling GHS07
Pictograms GMP,ISO9001,Halal,Kosher
Signal word Warning
Hazard statements Hazard statements: Not a hazardous substance or mixture according to Regulation (EC) No. 1272/2008.
Precautionary statements P264, P270, P301+P312, P330, P501
NFPA 704 (fire diamond) 2-1-0
Flash point > 134.3°C
Lethal dose or concentration LD₅₀ (oral, rat): 2,100 mg/kg
LD50 (median dose) LD50 (median dose): Mouse intravenous LD50: 220mg/kg
NIOSH 8013-86-3
REL (Recommended) REL (Recommended) of product 'Sodium Ferulate - Natural Extraction' is "0.2 g/person/day".
Related compounds
Related compounds Ferulic acid
Ethyl ferulate
Methyl ferulate