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Chemical Name: Sodium Dextran Sulfate
CAS Number: 9011-18-1
Synonyms: Dextran sulfate sodium salt, SDS
Recommended Use: Research, laboratory reagent
Supplier Information: Name, address, phone and emergency contact (user provides these details as required by local regulation)
Product Appearance: White to off-white powder or crystalline
Molecular Formula: Variable, typically C6H7Na3O14S3·xH2O
Molecular Weight: Varies (commonly reported as 5000–50,000 or higher based on source preparation)
GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Respiratory irritation
Label Elements: Warning, exclamation mark symbol
Hazard Statements: Causes skin and serious eye irritation. May cause respiratory tract irritation. Prolonged inhalation produces coughing and discomfort.
Precautionary Statements: Avoid breathing dust. Use only outdoors or in well-ventilated areas. Wear protective gloves, clothing, and eye protection.
Routes of Exposure: Inhalation, ingestion, eye, and skin contact
Emergency Overview: Powder can create dust clouds; can be irritating to mucous membranes
Sodium Dextran Sulfate: 90–100%
Impurities: May contain sodium chloride, trace organic contaminants, unreacted dextran (typically under 10%)
Formulation Notes: No hazardous stabilizers or additives detected in high-purity grades
Inhalation: Move person to fresh air. Keep comfortable for breathing. Seek medical attention if symptoms develop or persist.
Skin Contact: Wash thoroughly with soap and water. Remove contaminated clothing and footwear; wash before reuse. Get medical advice for persistent irritation.
Eye Contact: Rinse carefully with water for at least 15 minutes, holding eyelids apart. Remove contact lenses if present and easy to do. Continue rinsing and seek medical care for ongoing discomfort.
Ingestion: Rinse mouth. Do not induce vomiting. Give water to drink if conscious. Monitor for allergic or gastrointestinal symptoms. Medical supervision recommended.
Flammable Properties: Not classified as flammable but may burn under fire conditions, producing irritating and/or toxic fumes
Extinguishing Media: Water spray, dry chemical, carbon dioxide, or foam
Unsuitable Media: Direct water stream may spread powder
Protective Equipment: Self-contained breathing apparatus (SCBA), full firefighting gear
Specific Hazards: Sulfur oxides, carbon monoxide, carbon dioxide, sodium oxide may form during combustion
Fire Fighting Procedures: Cool containers with water spray. Isolate area. Prevent runoff into drains or watercourses.
Personal Precautions: Evacuate area. Wear appropriate respirator, gloves, lab coat, and goggles.
Environmental Precautions: Prevent spills from entering drains, soil, or surface water.
Containment Methods: Sweep up or vacuum without creating dust. Avoid dry sweeping if dust clouds form.
Cleanup Procedures: Collect material in suitable, labeled containers for disposal. Wash spill area with water and detergent.
Handling: Avoid dust generation and inhalation. Do not get in eyes, on skin, or clothing. Maintain good laboratory hygiene. Use in ventilated space.
Storage: Store in tightly sealed containers in a cool, dry place, away from incompatible substances such as strong oxidizers. Store away from food and drink.
Incompatibles: Strong acids, oxidizing agents. Avoid humidity that could degrade the product.
Engineering Controls: Use local exhaust ventilation or work under a chemical fume hood.
Exposure Limits: No established occupational exposure limits for sodium dextran sulfate; treat as a particulate nuisance dust (e.g. OSHA PEL for particulates not otherwise regulated: 15 mg/m3 total dust, 5 mg/m3 respirable fraction)
Personal Protective Equipment: Safety goggles, appropriate gloves (nitrile or equivalent), protective lab coat. In case of inadequate ventilation, use a dust mask or NIOSH-approved respirator.
Hygiene Measures: Wash hands after handling, remove contaminated clothing and wash before reuse. Do not eat, drink, or smoke while using the material.
Appearance: White to off-white powder or granules
Odor: Odorless
pH (1% solution): 6.0–8.0
Melting Point / Freezing Point: Decomposes before melting
Boiling Point: Not applicable (polymer)
Flash Point: Not applicable
Evaporation Rate: Not applicable
Flammability: Not flammable as supplied
Vapor Pressure: Not relevant
Solubility: Soluble in water
Partition Coefficient: Not determined
Decomposition Temperature: >200°C
Viscosity: Not available
Stability: Stable under recommended storage conditions.
Conditions to Avoid: Excessive moisture, heat, open flames
Incompatible Materials: Strong acids, oxidizing agents
Hazardous Decomposition Products: Carbon monoxide, carbon dioxide, sulfur oxides, sodium oxides
Polymerization: Hazardous polymerization does not occur under normal conditions
Acute Toxicity: Low acute toxicity expected based on studies with rodents and reported LD50 values (rat, oral >2000 mg/kg)
Skin/Eye Irritation: May cause moderate irritation upon contact
Respiratory Effects: Dust inhalation may affect airways, causing coughing and shortness of breath
Sensitization: Rare cases of skin or respiratory allergic reactions reported
Chronic Effects: No evidence of mutagenicity, carcinogenic or reproductive toxicity found in standard studies
Target Organs: Lungs (if inhaled as dust), skin, eyes
Additional Information: Individuals with pre-existing allergies or respiratory conditions may be at greater risk from exposure
Toxicity to Aquatic Life: No acute harm expected in typical laboratory release concentrations. Limited aquatic data; high concentrations may affect biological oxygen demand.
Persistence and Degradability: Gradual biodegradation by soil and water microorganisms
Bioaccumulation Potential: Expected to be low due to high solubility and large molecular size
Mobility in Soil: Soluble in water, potential for movement in groundwater if large quantities released
Other Ecological Effects: Avoid direct release to the environment; laboratory procedures should minimize discharge
Disposal Methods: Treat as non-hazardous laboratory chemical waste. Small quantities can be diluted and flushed with water to drain if local regulations allow. Large or bulk waste should be incinerated or landfilled in accordance with municipal, regional, and national regulations.
Container Disposal: Triple rinse containers, then offer for recycling or disposal according to local rules.
Precautions: Avoid uncontrolled release to environment. Maintain all records and documentation of waste disposal.
UN Number: Not classified as a dangerous good for transport
Transport Hazard Class: Not regulated
Packing Group: Not applicable
Labeling Requirements: Standard labeling for laboratory chemicals
Special Precautions: Prevent packaging breaches. Use dry, sealed bags or containers. Protect from humidity during shipment.
International Transport: Not considered a marine or air pollutant under current regulations
TSCA Status: Listed or exempt in most jurisdictions
DSL/NDSL (Canada): Listed
REACH (EU): Registration not required for this polymer under current tonnage thresholds
OSHA Hazard Communication: Classified as hazardous for skin, eye, and respiratory irritation only
WHMIS (Canada): D2B – Toxic Material Causing Other Toxic Effects
Additional Regulations: Product not listed as carcinogen by IARC, NTP, OSHA. Users comply with all local, regional, and federal laws relating to use, storage, transport, and disposal.
