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Sineconazole Material Safety Data Sheet

Identification

Product Name: Sineconazole
Chemical Formula: C15H17Cl2N3O2
Synonyms: Sineconazol, Fungicide Sineconazole
CAS Number: 94749-62-9
Recommended Use: Agricultural fungicide for plant protection
Supplier Details: Manufacturer and distributor information supplied on container label
Emergency Contact: Local poison control center, emergency services contact number listed on product label

Hazard Identification

Hazard Classification: Acute toxicity (oral, dermal, inhalation), Eye irritation, Skin sensitization
GHS Label Elements: Danger
Hazard Statements: Harmful if swallowed, Toxic in contact with skin, Causes serious eye irritation, May cause skin sensitization
Pictograms: Skull and crossbones, Exclamation mark
Routes of Exposure: Inhalation, skin and eye contact, ingestion
Precautionary Statements: Wear protective gloves and eye protection, Avoid breathing dust or spray, Do not eat or drink during handling, Wash thoroughly after use

Composition / Information on Ingredients

Active Ingredient: Sineconazole
Chemical Name: 1-[(2-Chlorophenyl)methyl]-1H-1,2,4-triazole-3-methanol
Other Ingredients: Inert materials used in formulation
Concentration: Sineconazole concentration varies based on formulation, typically 10-25% active
Impurities: Information provided by manufacturer if present in significant concentrations

First Aid Measures

Inhalation: Remove to fresh air, support breathing if needed, seek immediate medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water, wash with soap
Eye Contact: Rinse cautiously with water for at least 15 minutes, remove contact lenses if easy, continue rinsing
Ingestion: Do not induce vomiting, rinse mouth, seek medical attention without delay
Advice for Physicians: Treat symptomatically based on clinical judgement

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, water spray
Unsuitable Extinguishing Media: High-pressure water streams may spread contamination
Special Hazards: Combustion may produce toxic fumes of hydrogen chloride, nitrogen oxides, carbon oxides
Protective Equipment for Firefighters: Self-contained breathing apparatus, full protective clothing
Specific Procedures: Prevent runoff from contaminating water sources, cool containers exposed to flames with water spray

Accidental Release Measures

Personal Precautions: Evacuate area, use appropriate personal protective equipment including gloves, goggles, and respirators
Environmental Precautions: Prevent entry into drains, sewers, or water bodies
Methods for Containment: Absorb spill with inert material such as sand or earth, collect and transfer to suitable disposal container
Cleanup Procedures: Wash area thoroughly with detergent and water after removal of spilled material, ventilate the area

Handling and Storage

Handling Precautions: Use only outdoors or in well-ventilated areas, avoid skin and eye contact, avoid inhalation of dust or mist
Safe Storage Conditions: Store in tightly closed, original container, keep in a cool dry place away from sunlight, food, drink, and animal feed
Specific Storage Requirements: Keep containers upright and secure, segregate from incompatible chemical classes, use secondary containment where appropriate
Other Recommendations: Do not reuse empty containers, clean containers thoroughly before disposal

Exposure Controls and Personal Protection

Occupational Exposure Limits: No established occupational exposure limits for Sineconazole
Engineering Controls: Use local exhaust ventilation to minimize dust or spray
Personal Protective Equipment: Chemical resistant gloves and apron, safety goggles, respiratory protection if airborne concentrations are high
Hygiene Measures: Wash hands and face after handling, do not eat, drink, or smoke until hands are washed, remove contaminated clothing before breaks

Physical and Chemical Properties

Appearance: White to off-white crystalline powder
Odor: Odorless or slight chemical odor
Melting Point: 78-80°C
Boiling Point: Decomposes before boiling
Density: Approximately 1.25 g/cm3
Solubility: Slightly soluble in water, soluble in organic solvents such as acetone, methanol, dichloromethane
Vapor Pressure: Very low at room temperature
pH (1% solution): 7-8
Partition Coefficient (log Kow): 3.5-4.0
Flash Point: Not flammable under normal conditions

Stability and Reactivity

Chemical Stability: Stable under normal storage conditions
Conditions to Avoid: Moisture, heat, direct sunlight, strong oxidizing agents
Incompatible Materials: Strong acids, strong bases, oxidizers
Hazardous Decomposition Products: Hydrogen chloride, nitrogen oxides, carbon monoxide, carbon dioxide
Polymerization: Will not occur under recommended storage and use conditions

Toxicological Information

Acute Toxicity (Oral): LD50 (rat) 200-600 mg/kg
Acute Toxicity (Dermal): LD50 (rat) >2000 mg/kg
Acute Toxicity (Inhalation): LC50 (rat, 4h) >2 mg/L
Skin Irritation: Moderately irritating
Eye Irritation: Causes severe eye irritation
Respiratory Sensitization: No reliable data
Long-term Exposure Risks: Possible liver and kidney damage at high doses in animal studies
Carcinogenicity: Not classified as carcinogen based on available evidence
Mutagenicity: Not mutagenic in standard tests
Reproductive Toxicity: Data suggest no specific reproductive risk from normal handling

Ecological Information

Ecotoxicity: Very toxic to aquatic life, including fish, daphnia, and algae
Persistence and Degradability: Moderately persistent in soil and water, breakdown products can remain for weeks to months
Bioaccumulation Potential: Moderate potential based on partition coefficient
Mobility in Soil: Low to moderate, substance can bind to soil particles
Other Adverse Effects: May disrupt aquatic ecosystems if released into water bodies, avoid contamination of watercourses and drains

Disposal Considerations

Waste Treatment Methods: Incinerate in approved facility, or bury at licensed landfill site in accordance with local regulations
Product Disposal: Do not discharge into drains, soil, or surface waters
Container Disposal: Triple rinse and puncture or crush, dispose of through hazardous waste facility
Other Information: Compliance with local, regional, and national regulations is required for all disposal activities

Transport Information

UN Number: 3077
Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (contains Sineconazole)
Transport Hazard Class: 9
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Do not transport with foodstuffs or animal feed, keep container sealed during transport, follow spill response plan in case of accident

Regulatory Information

Safety, Health, and Environmental Regulations: Registered pesticide under national and international regulatory bodies
Signal Word and Labeling: Signal word “Danger” required on packaging
Restrictions: Approved for professional agricultural use, not intended for domestic use
Reporting Requirements: Subject to notification and reporting under various chemical inventories and hazardous materials regulations
Additional Information: Consult specific local and national regulatory frameworks for restrictions and worker protection requirements, SDS must be available onsite at all times