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Material Safety Data Sheet: Sec-Amylamine

Identification

Product Name: Sec-Amylamine
Synonyms: 2-Pentanamine, sec-pentylamine
Chemical Family: Aliphatic amines
CAS Number: 623-33-6
Recommended Use: Intermediate in organic synthesis, reagent in laboratories
Manufacturer/Supplier: [To be filled by relevant party]
Contact Information: [To be filled by relevant party, include address, phone number, emergency contact]

Hazard Identification

GHS Classification: Flammable liquid (Category 3), Acute toxicity oral (Category 4), Acute toxicity dermal (Category 3), Serious eye irritation (Category 2A), Skin corrosion/irritation (Category 2)
Label Elements: Signal word: Danger; Hazard statements: Flammable liquid and vapor, Harmful if swallowed or in contact with skin, Causes skin and serious eye irritation
Precautionary Statements: Keep away from heat and sources of ignition, Avoid breathing vapors, Wear protective gloves and eye protection, Wash hands thoroughly after use
Pictograms: Flame, Exclamation mark, Corrosive

Composition / Information on Ingredients

Chemical Identity: Sec-Amylamine
CAS Number: 623-33-6
Concentration: >99% (by weight)
Impurities: Trace amounts of primary and tertiary amylamines, not considered hazardous under normal use

First Aid Measures

Inhalation: Move person into fresh air, keep at rest, seek medical attention if symptoms develop or persist like coughing, throat irritation, or dizziness
Skin Contact: Remove contaminated clothing, rinse skin with plenty of water for at least 15 minutes, seek medical help for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if easy, continue rinsing, get prompt medical evaluation if redness or pain continues
Ingestion: Rinse mouth thoroughly, do not induce vomiting, seek immediate medical attention, give nothing by mouth to an unconscious person

Fire-Fighting Measures

Suitable Extinguishing Media: Carbon dioxide, dry chemical powder, alcohol-resistant foam, water spray
Unsuitable Extinguishing Media: Full water jet can spread flammable liquid
Hazards from Combustion: Fires involving this material can produce toxic fumes including nitrogen oxides, carbon monoxide, carbon dioxide
Protective Equipment for Firefighters: Full protective gear and self-contained breathing apparatus, avoid inhaling vapors or combustion fumes
Specific Hazards: Vapor may travel and ignite at a distance, containers exposed to fire may explode due to pressure build-up

Accidental Release Measures

Personal Precautions: Evacuate area, ventilate space, eliminate all ignition sources, wear chemical splash goggles, gloves, and apron
Environmental Precautions: Prevent entry into waterways, drains, soil or vegetation, inform local authorities if spill cannot be contained
Cleanup Methods: Absorb with inert material like sand or vermiculite, collect in closed containers, flush area with water after removal, properly dispose of waste

Handling and Storage

Precautions for Safe Handling: Avoid contact with skin, eyes, clothing, use only with adequate ventilation, keep away from heat, sparks, and open flames, use explosion-proof equipment, ground all containers
Conditions for Safe Storage: Store in a cool, dry, well-ventilated place, keep container tightly closed, segregate from oxidizers, acids, and sources of ignition, do not store near food, beverages, or incompatible chemicals
Incompatible Materials: Acid chlorides, acid anhydrides, strong acids, oxidizing agents

Exposure Controls and Personal Protection

Occupational Exposure Limits: No ACGIH or OSHA PEL specifically assigned, recommend maintaining exposures as low as possible
Engineering Controls: Use fume hoods, process enclosures, and good industrial hygiene practices
Personal Protective Equipment: Chemical-resistant gloves (nitrile, neoprene), safety goggles, lab coat or apron, in case of insufficient ventilation use approved organic vapor respirator
Hygiene Measures: Wash hands, face, and exposed skin before eating or drinking, launder contaminated clothing before reuse

Physical and Chemical Properties

Appearance: Clear colorless to slightly yellow liquid
Odor: Ammoniacal, pungent
Molecular Formula: C5H13N
Molecular Weight: 87.16 g/mol
Boiling Point: 95-100°C (203-212°F)
Melting Point: -70°C (-94°F)
Flash Point: 21°C (70°F)
Vapor Pressure: 80 mm Hg at 25°C
Density: 0.758 g/cm³ at 20°C
Solubility: Miscible with water, alcohol, ether
pH (1% solution): Alkaline
Auto-ignition Temperature: 285°C (545°F)

Stability and Reactivity

Chemical Stability: Stable under recommended conditions of use and storage
Hazardous Reactions: Reacts with strong oxidizers, acids, acid chlorides, acid anhydrides, produces heat and flammable hydrogen gas
Decomposition Products: Exposed to heat or fire, generates nitrogen oxides, carbon monoxide, and other toxic vapors
Conditions to Avoid: Sparks, open flames, static discharge, high temperatures, incompatible substances

Toxicological Information

Routes of Exposure: Inhalation, skin and eye contact, ingestion
Acute Toxicity: Oral LD50 (rat): 165 mg/kg; causes nausea, vomiting, headache, CNS depression
Dermal Toxicity: Harmful through skin absorption, risk of burns, irritation, dermatitis with prolonged exposure
Eye Effects: Severe irritation, tearing, possible corneal injury
Chronic Effects: Prolonged exposure may cause liver, kidney, and nervous system effects
Cancer Information: No evidence of carcinogenicity found in available data
Sensitization: Not expected to cause respiratory or skin sensitization from available data

Ecological Information

Environmental Fate: Volatile, biodegradable, may contribute to formation of ground level ozone, mobile in soil
Toxicity to Aquatic Life: Moderately toxic to fish and aquatic invertebrates, LC50 (fish, 96h): 27 mg/L
Persistence and Degradability: Expected to be readily biodegradable in water and soil
Bioaccumulation: Not expected to bioaccumulate due to breakdown in environment
Other Adverse Effects: Avoid large releases to waterways; can cause algal bloom due to nitrogen content

Disposal Considerations

Waste Generation: Collect and dispose of as hazardous chemical waste
Methods of Disposal: Consult federal, state, and local regulations, use licensed chemical waste incinerator with afterburner and scrubber
Contaminated Packaging: Rinse thoroughly, render incapable of reuse, dispose or send for drum reconditioning
Precautions: Avoid discharge to environment, document disposal and follow best practice standards

Transport Information

UN Number: UN 2733
Proper Shipping Name: Amines, liquid, corrosive, flammable, n.o.s. (sec-amylamine)
Transport Hazard Class: 3 (Flammable liquid), 8 (Corrosive)
Packing Group: II
Environmental Hazards: Not classified as marine pollutant under IMDG
Special Precautions: Secure containers, ensure proper labeling, segregate from incompatible cargo, emergency response required for large spills or leaks

Regulatory Information

OSHA: Regulated as hazardous, subject to labeling and PPE mandates
TSCA: Listed in TSCA Inventory
RCRA: Classified hazardous waste when discarded
SARA Title III: Immediate health hazard, fire hazard
EU Regulation: Classified under CLP as Acute Tox. 4, Flam. Liq. 3, Skin Corr. 1B, Eye Dam. 1
Canadian WHMIS: Listed as Class B-2 (Flammable Liquids), Class D-1B (Toxic Material)
Other: Local, state, and national chemical control laws apply, always consult regulatory agency for exact compliance obligations