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Chemical Name: Scopolamine Butylbromide
Common Names: Hyoscine Butylbromide
CAS Number: 149-64-4
Appearance: White or almost white crystalline powder
Odor: Odorless
Uses: Relief of abdominal pain, cramps, and spasms, often found in tablets or injectable form
Main Risks: Irritating to eyes and respiratory system, can cause drowsiness, confusion, dry mouth, blurred vision
Health Hazards: May provoke tachycardia, urinary retention, constipation, and in higher doses, hallucinations or agitation
Environmental Risks: Toxic to aquatic organisms, especially in concentrated form
Signal Words: Warning for accidental exposure, caution required for those with glaucoma or myasthenia gravis
Main Ingredient: Scopolamine Butylbromide, purity varies with product form
Formulation Carriers: Excipients in tablet or solution form may include lactose monohydrate, magnesium stearate, or sodium chloride
Impurities: Small amounts of related tropane alkaloids may occur depending on synthetic route, not usually in pharmacological doses
Inhalation: Remove to fresh air, seek medical attention if symptoms occur
Skin Contact: Rinse thoroughly with water, remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes, get medical help if irritation persists
Ingestion: Seek immediate medical attention; effects can include central nervous system symptoms and antimuscarinic toxicity signs
Suitable Extinguishing Media: Use water spray, foam, or dry chemical for small fires; do not use strong jets that might spread powder
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides, toxic fumes may develop if burned
Protective Equipment: Self-contained breathing apparatus, protective clothing prevent inhalation and contact during fire response
Spill Cleanup: Wear gloves and a dust mask, avoid creating dust clouds, sweep up and collect in suitable containers
Environmental Precaution: Prevent release into drains or rivers, not suitable for flushing into water systems
Decontamination: After cleanup, wash affected surfaces with soap and water; ventilate area well
Personal Protection: Do not touch spills without adequate skin and respiratory protection
Safe Handling: Use only in well-ventilated spaces, minimize dust formation, avoid inhalation or contact with eyes or mouth
Storage Recommendations: Store at room temperature in tightly closed containers away from moisture, direct sunlight, and incompatible substances
Incompatibles: Strong oxidizing agents, acids, and bases may react with the compound
Hygiene: Wash hands thoroughly after handling; do not eat, drink, or smoke during use
Engineering Controls: Work under fume extraction hoods or with good ventilation; keep airborne concentrations low
Personal Protection: Wear standard laboratory gloves, safety goggles, lab coats; for spills or bulk handling, use respirators
Exposure Limits: No established occupational exposure limits in most regions, though burdens fall under general dust and chemical guidelines
Environmental Controls: Avoid release to environment, especially aquatic ecosystems
Appearance: White crystalline powder
Odor: None
Melting Point: 190–200°C (decomposition)
Solubility: Soluble in water and ethanol
pH (1% Solution): Neutral to slightly alkaline
Molecular Weight: 400.46 g/mol
Chemical Stability: Stable under normal conditions if kept dry and in the dark
Conditions to Avoid: Heat, direct sunlight, contact with acids and oxidizers
Hazardous Decomposition: Decomposes to toxic vapors when burned, forming nitrogen oxides and carbon monoxide
Reactivity Notes: Not prone to violent reactions under typical storage and use
Acute Toxicity: Low to moderate toxicity by ingestion; central nervous effects at high doses
Symptoms: Dry mouth, blurred vision, drowsiness, agitation, urinary retention, tachycardia at significant exposures
Chronic Exposure: Long-term effects not well-studied in non-therapeutic settings; repeated overuse raises concern for cognitive impact
At-Risk Groups: Elderly, children, and people with certain health conditions face higher risk at lower doses, especially for anticholinergic symptoms
Environmental Impact: Potentially toxic to aquatic organisms if released in large quantities
Persistence: Slow degradation in soil and water, risk for accumulation in poorly managed waste
Bioaccumulation: No evidence of significant build-up in food chains, but risks remain for toxic effects in local water sources
Precautionary Steps: Avoid flushing into sewers, keep waste secured for safe disposal
Preferred Disposal: Controlled chemical incineration or hazardous waste landfill in line with local regulations
Packaging Disposal: Rinse and discard packaging as hazardous unless decontaminated
Avoid: Disposing in household garbage, sewage, or general landfill due to toxicity potential; illegal dumping threatens public safety and local ecology
Regulatory Caution: Follow specific national guidance for pharmaceutical and chemical waste
Shipping Category: Generally shipped as a hazardous material under pharmaceutical or lab chemical codes
Container Requirements: Use tightly sealed, appropriately labeled containers with protective outer packaging
Handling During Transit: Prevent falls, breakage, or leakage; limit worker exposure during handling
Documentation: Accompany with detailed hazard information and permit documentation required by authorities
Pharmaceutical Regulation: Classified as a prescription drug in most jurisdictions, tightly controlled in medical use
Chemical Legislation: Covered under chemical safety regulations, often falling into controlled substances lists given its pharmacology
Workplace Controls: Occupational exposure standards may be in place under health and safety law, requiring training and PPE for handlers
Environmental Law: Restrictions for release, reporting, and waste management are in effect in many regions to prevent environmental and health risks
