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Product Name: S-Adenosylmethionine Disulfate P-Toluenesulfonate
Chemical Formula: C15H24N6O5S2·C7H8O3S
Synonyms: SAMe Tosylate, S-Adenosyl-L-methionine p-toluenesulfonate
CAS Number: 97540-22-2
Recommended Use: Active pharmaceutical ingredient, dietary supplement
Supplier: [Company Name and Contact Information]
Classification: May cause skin and eye irritation; not considered hazardous under GHS criteria
Signal Word: Warning
Hazard Statements: May cause mild irritation to mucous membranes, eyes, and skin
Precautionary Statements: Avoid breathing dust; wash hands thoroughly after handling; use eye protection and gloves
Other Hazards: Combustible dust may form if the powder spreads in air; keep away from ignition sources
Chemical Identity: S-Adenosylmethionine Disulfate P-Toluenesulfonate
Percentage: Approximately 99% active ingredient
Impurities: May contain small amounts of related organic impurities (<1%)
EC Number: Not available
Molecular Weight: About 766.9 g/mol
Inhalation: Move to fresh air. Seek medical attention if symptoms appear.
Skin: Wash affected area with plenty of water and soap. Remove contaminated clothing. If irritation persists, get medical advice.
Eye Contact: Rinse opened eye for several minutes under running water. Remove contact lenses if possible. Get medical attention if discomfort continues.
Ingestion: Rinse mouth with water. Seek immediate medical attention if unwell or if a large amount has been swallowed.
Most Important Symptoms: Redness, irritation, possible gastrointestinal discomfort
Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or foam
Specific Hazards: Combustible material; fumes may contain carbon oxides, nitrogen oxides, sulfur oxides, and toluene
Protective Equipment: Wear full protective clothing and self-contained breathing apparatus
Special Precautions for Firefighters: Cool exposed containers with water; avoid runoff into drains or sewers
Personal Precautions: Use personal protective equipment; avoid dust formation; ensure good ventilation
Environmental Precautions: Prevent spilled product from entering soil, drains, and watercourses
Cleanup Methods: Sweep or vacuum up and place in suitable container for disposal; clean contaminated surfaces with water and detergent; ventilate area
Handling: Avoid contact with skin, eyes, and clothing; prevent dust build-up; use only in well-ventilated areas; do not eat, drink, or smoke while handling
Storage: Store in tightly closed, labeled containers in a cool, dry, well-ventilated place; protect from light, heat, and moisture; keep away from incompatible substances such as strong oxidizers and acids
Exposure Limits: No workplace exposure limit established
Engineering Controls: Use local and general exhaust to minimize dust formation; use closed systems or adequate containment
Personal Protective Equipment: Wear chemical-resistant gloves, lab coat or apron, safety goggles; provide eye-wash stations and safety showers where appropriate
Respiratory Protection: Use a NIOSH-approved particulate respirator in dusty environments
Appearance: White to off-white crystalline powder
Odor: Odorless
pH (1% solution): 2.0–3.0 (acidic)
Melting Point: Decomposes above 180°C
Solubility in Water: Freely soluble
Flash Point: Not established
Boiling Point: Not applicable (decomposes before boiling)
Vapor Pressure: Not relevant (solid)
Relative Density: About 1.2 g/cm³
Partition Coefficient (Log Pow): Not determined
Chemical Stability: Stable under recommended storage conditions
Reactivity: May react with strong oxidizing agents and strong acids
Conditions to Avoid: Heat, moisture, open flames, exposure to light
Incompatible Materials: Strong oxidizers, acids, bases
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides, p-toluenesulfonate fumes
Acute Toxicity: No data on acute toxicity in humans; may cause irritation to mucous membranes, eyes, skin
Chronic Toxicity: No reports of chronic toxicity; generally recognized as safe at recommended doses in dietary supplements
Routes of Exposure: Inhalation, ingestion, dermal, eye
Symptoms: Mild irritation, possible gastrointestinal effects if ingested in large quantities
Carcinogenicity/Mutagenicity: Not classified as carcinogenic or mutagenic by IARC, NTP, or OSHA
Reproductive Toxicity: No known effects
Toxicity to Aquatic Life: Not expected to be hazardous, but limited data available
Persistence and Degradability: Product expected to degrade under environmental conditions
Bioaccumulative Potential: Not expected to bioaccumulate
Mobility in Soil: Highly soluble, may leach in soil
Other Adverse Effects: Avoid release to the environment; prevent contamination of waterways
Waste Treatment Methods: Dispose of material as non-hazardous chemical waste, in accordance with local, state, and federal regulations
Contaminated Packaging: Rinse containers and dispose of as chemical waste
Disposal Precautions: Prevent product release to drain, surface water, or soil
UN Number: Not classified as a dangerous good for transport
Proper Shipping Name: S-Adenosylmethionine Disulfate P-Toluenesulfonate
Transport Hazard Class: Not regulated
Packing Group: Not regulated
Environmental Hazards: None known
Special Precautions for User: Secure packaging to avoid dust emission and direct contact
OSHA: Not classified as hazardous
TSCA Status: Listed or exempt
DSL/NDSL Status: Not listed
REACH Registration: Exempt or not required
Other Regulations: Subject to regulations related to pharmaceuticals and dietary supplements; specific regulations may apply for workplace exposure and environmental release depending on local requirements
