© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Roxarsone
Chemical Name: 4-Hydroxy-3-nitrobenzenearsonic acid
CAS Number: 121-19-7
Synonyms: Roxarsone, 4-Hydroxy-3-nitrophenylarsonic acid
Recommended Use: Used in animal feed as a growth promoter, particularly poultry
Manufacturer: Obtain contact details through supplier or label
Emergency Phone: Refer to local regulations for poison control centers and chemical emergency hotlines
Restrictions: Not for use in foods or pharmaceuticals intended for direct human consumption
GHS Classification: Acute toxicity (oral, dermal, inhalation) Category 2; Carcinogenicity Category 1; Specific Target Organ Toxicity – Repeated Exposure Category 2
Signal Word: Danger
Hazard Statements: Causes damage to organs through prolonged or repeated exposure; Suspected of causing cancer; Very toxic if swallowed or inhaled
Pictogram: Skull and crossbones, health hazard, exclamation mark
Precautionary Statements: Do not breathe dust; If on skin: wash with plenty of soap and water; If inhaled: remove person to fresh air and keep comfortable; Seek medical advice if feeling unwell; Contaminated work clothing must not be allowed out of workplace
Main Ingredient: Roxarsone
Concentration: 98–100%
Impurities: Traces of nitrated phenolic compounds, arsenic oxides
Molecular Formula: C6H6AsNO6
Molecular Weight: 263.04 g/mol
Inhalation: Remove from area to fresh air; Monitor for respiratory distress; Seek medical attention immediately
Skin Contact: Remove contaminated clothing; Rinse skin with copious amounts of water and soap for at least 15 minutes; Seek medical assistance if irritation develops
Eye Contact: Rinse with flowing water for at least 15 minutes; Remove contact lenses if easy; Seek prompt medical examination, even if no symptoms
Ingestion: Rinse mouth thoroughly; Do not induce vomiting; Never give anything by mouth to an unconscious person; Get medical attention straight away
Most Important Symptoms and Effects: Headache, nausea, vomiting, abdominal pain, skin irritation, respiratory tract symptoms
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Extinguishing Media: Avoid direct water jet
Specific Hazards: Arsenic and nitrogen oxides may be released on combustion; risk of toxic smoke
Protective Equipment: Self-contained breathing apparatus (SCBA) and full protective gear
Advice for Firefighters: Fight fire from upwind; Cool containers with water spray to prevent rupture; Avoid inhalation of fumes; Consider evacuation of area
Personal Precautions: Wear respiratory protection, chemical-resistant gloves, goggles, and protective clothing
Environmental Precautions: Prevent material from entering drains, sewers, or watercourses; Notify authorities if substantial spill reaches environment
Methods for Clean-up: Sweep up carefully, minimizing dust; Shovel into labeled, sealed containers for disposal; Wash spill area with plenty of water and detergent; Ventilate enclosed spaces
Handling: Use only with adequate ventilation or respiratory protection; Avoid generation and inhalation of dust; Never eat, drink, or smoke in working area; Avoid prolonged or repeated exposure
Storage: Store in original container, tightly closed, in a cool, dry, well-ventilated place; Protect from moisture and sources of ignition; Keep away from incompatible substances such as strong acids, oxidizers, reducing agents
Other Precautions: Clearly label storage containers; Store away from food, animal feed, and drinking water; Limit access to authorized personnel only
Exposure Limits: Occupational exposure limit values for arsenic compounds differ by jurisdiction (e.g., OSHA PEL 0.01 mg/m³ for arsenic)
Engineering Controls: Use local exhaust ventilation or process enclosure; Eyewash stations and safety showers within immediate work area
Personal Protective Equipment: Chemical-resistant gloves (nitrile or neoprene), goggles or face shield, lab coat or protective clothing; Approved respirators in situations where dust/vapors may form
Hygiene Measures: Wash hands before eating, drinking, or smoking; Remove and wash contaminated clothing before reuse; Do not touch face, mouth, or eyes when working with this product
Appearance: Yellow to light brown crystalline powder
Odor: Odorless
pH: 4.2 (1% solution in water)
Melting Point: Decomposes at 198-199°C (388-390°F)
Boiling Point: Not applicable (decomposes on heating)
Flash Point: Not available
Evaporation Rate: Not relevant for this class
Flammability: Not flammable, may support combustion under extreme conditions
Vapor Pressure: Negligible
Solubility: Slightly soluble in water; insoluble in most organic solvents
Partition Coefficient (log Kow): Not determined
Density: 1.68 g/cm³
Chemical Stability: Stable at standard temperatures and pressures; decomposes upon heating
Reactivity: Reacts with powerful oxidizers and strong acids
Hazardous Decomposition Products: May form arsenic oxides, nitrogen oxides, and carbon oxides
Incompatible Materials: Strong oxidizers, reducing agents, strong acids, bases
Polymerization: Does not occur under normal processing
Acute Toxicity: LD50 (oral, rat) approximately 390 mg/kg; highly toxic by ingestion or inhalation
Sensitization: May cause allergic skin reaction after repeated exposure
Chronic Effects: Chronic poisoning can damage liver, kidneys, and nerves; Carcinogenic in humans based on arsenic content
Carcinogenicity: Arsenic compounds listed as Group 1 carcinogen (IARC); Roxarsone may pose similar risks; No safe exposure level established
Symptoms of Exposure: Headache, dizziness, nausea, vomiting, diarrhea, confusion, weakness, skin eruptions
Target Organs: Liver, kidneys, skin, nervous system
Toxicity to Aquatic Life: Highly toxic to aquatic organisms (fish, daphnia, algae) due to arsenic content
Persistence and Degradability: Roxarsone converts to more toxic inorganic arsenic in soil; Persists in environment for weeks or months
Bioaccumulation: Arsenic compounds bioaccumulate in aquatic food chains; Roxarsone may result in long-term exposure to ecosystems
Mobility in Soil: Mobile under certain conditions; can pollute groundwater
Other Adverse Effects: Poses health threat to organisms in soil and water; Residues may accumulate in animal tissue and move up food chain
Waste Treatment Options: Dispose of as hazardous waste in accordance with local, regional, and national regulations
Disposal Methods: Do not discharge to sewer or water bodies; Chemical incineration, landfilling at designated sites, or controlled chemical destruction
Packaging Disposal: Triple rinse empty containers; render unusable prior to disposal at approved facility
Precautions: Ask permitted waste contractors for advice; Do not reuse packaging for any purpose
UN Number: 1557 (Arsenical pesticides, solid, toxic, n.o.s.)
UN Proper Shipping Name: Toxic solid, inorganic, n.o.s. (contains Roxarsone, arsenic compound)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II (substances presenting medium danger)
Label Required: Toxic
Environmental Hazards: Marine pollutant; avoid spills near waterways
Special Transport Precautions: Secure containers to prevent movement and breakage; Keep separate from food, feed, and animal products
Transport in Bulk: Not recommended without careful containment
U.S. EPA: Listed as hazardous substance (RCRA: D004 arsenic waste); subject to federal restrictions on use and disposal
OSHA: Regulated under hazardous substances standards; must comply with permissible exposure limits and hazard communication rules
IARC: Group 1 carcinogen (for inorganic arsenic compounds)
TSCA: Listed, with restrictions on use; must meet reporting and handling requirements
EU Regulations: Classified as toxic; subject to REACH reporting and authorization; Banned for use as animal feed additive in many regions
Other Information: Comply with all local and national laws regarding use, transport, and disposal; Roxarsone use suspended or prohibited in many countries in response to environmental and public health concerns
