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Riboflavin Sodium Phosphate Material Safety Data Sheet (MSDS)

Identification

Product Name: Riboflavin Sodium Phosphate
Chemical Name: Riboflavin 5’-Sodium Phosphate
Chemical Formula: C17H19N4NaO9P
Synonyms: Sodium Riboflavin 5’-Phosphate, Vitamin B2 Sodium Phosphate
Manufacturer/Supplier: Listed on product packaging or supply documents
Recommended Use: Nutritional supplement, pharmaceutical ingredient
Contact Information: Emergency phone and address as found on manufacturer labels

Hazard Identification

GHS Classification: Not classed as hazardous under GHS criteria
Signal Word: None
Hazard Statements: Not expected to produce hazardous effects under normal use
Precautionary Statements: Prevent dust formation, avoid inhalation, keep away from eyes and skin
Potential Health Effects: May be mildly irritating to eyes and skin with direct, prolonged exposure; ingestion in large quantities can cause stomach upset
Environment: Not classified as environmentally hazardous, but minimize release to soil and waterways

Composition / Information on Ingredients

Chemical Identity: Riboflavin Sodium Phosphate
CAS Number: 130-40-5
Content: Greater than 95% purity
Other Ingredients: Trace moisture or minor stabilizers may appear in some samples

First Aid Measures

Inhalation: Move exposed person to fresh air immediately; offer water if throat discomfort continues
Eye Contact: Rinse eyes gently with water for several minutes; remove contact lenses if present
Skin Contact: Wash affected area with soap and plenty of water; seek medical attention if irritation increases
Ingestion: Rinse mouth, drink water to dilute, do not induce vomiting; consult a physician for large ingestions or ongoing symptoms
Symptoms to Watch: Redness, mild irritation, abdominal discomfort

Fire-Fighting Measures

Suitable Extinguishing Media: Dry chemical, CO2, water spray, foam
Unsuitable Extinguishing Media: High-pressure water jets
Special Protective Equipment: Full protective clothing and self-contained breathing apparatus for responders
Specific Hazards: Dusts may ignite when exposed to strong ignition sources, creating a risk of fine particulate explosion; combustion produces carbon oxides, possible nitrogen or phosphorus oxides
Advice for Firefighters: Move containers from fire area if possible, avoid inhalation of smoke

Accidental Release Measures

Personal Precautions: Use dust mask, gloves, splash goggles; ensure good air ventilation
Environmental Precautions: Prevent entry into drains or surrounding environment; contain spillage to prevent runoff
Cleanup Methods: Sweep or vacuum up spillage; avoid generating dust, collect into suitable containers for safe disposal; wash area with water and detergent

Handling and Storage

Handling: Avoid creating dust clouds; use local exhaust ventilation; wear protective gloves, glasses
Storage Conditions: Store in tightly sealed containers; keep in cool, dry location out of direct sunlight; avoid contact with incompatible materials like strong oxidizers
Storage Temperature: Do not allow to freeze or overheat; maintain under 25°C (77°F)

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust for large-scale operations; keep working area clean to minimize airborne dust
Personal Protective Equipment (PPE): Eye protection (goggles), gloves (nitrile or similar), dust mask or respirator as necessary
Hygiene Measures: Wash hands after handling, avoid eating or drinking in the work area, change contaminated clothing promptly
Occupational Exposure Limits: No established limits for this substance; general dust exposure standards (e.g., OSHA PEL for particulates) apply

Physical and Chemical Properties

Appearance: Yellow to orange fine powder
Odor: Odorless
Solubility: Highly soluble in water
pH: 6.0–7.5 (1% solution in water)
Melting Point: Decomposes prior to melting
Boiling Point: Not applicable (decomposes)
Flash Point: Not determined
Vapor Pressure: Not applicable (non-volatile)
Density: 0.8–1.0 g/cm³
Partition Coefficient (n-octanol/water): Not available

Stability and Reactivity

Chemical Stability: Stable under normal handling and storage conditions
Conditions to Avoid: Excessive heat, sunlight, moisture, strong oxidizing agents
Incompatible Materials: Strong acids, strong oxidizers
Hazardous Decomposition Products: Thermal decomposition generates carbon, nitrogen, and phosphorus oxides
Polymerization: Will not occur

Toxicological Information

Acute Toxicity: Low oral toxicity, not considered acutely toxic by ingestion
Skin Contact: May cause mild irritation with prolonged exposure
Eye Contact: Can provoke mild irritation, redness, or discomfort
Inhalation: Overexposure to dust may irritate respiratory tract
Chronic Effects: Not recognized as causing chronic toxicity; vitamin B2 overdose from excessive long-term use by ingestion can create yellow urine but rarely causes toxic effects
Sensitization: No known sensitizing effects

Ecological Information

Aquatic Toxicity: Low toxicity; data indicates minimal environmental harm at realistic exposure levels
Persistence and Degradability: Readily biodegradable; does not bioaccumulate
Mobility in Soil: Highly water-soluble; can travel with surface water runoff
Other Adverse Effects: Not likely to pose risk to aquatic organisms or plants at low concentrations

Disposal Considerations

Waste Treatment Methods: Dispose of in accordance with local, regional, and national regulations; incineration or landfill in approved sites may be suitable
Packaging Disposal: Contaminated containers should be emptied completely and delivered to approved waste handlers; rinse packaging if possible before disposal
Prohibition: Do not dispose of in natural waterways, do not release undiluted to environment

Transport Information

UN Number: Not regulated
UN Proper Shipping Name: Not regulated
Transport Hazard Class: Not classified as dangerous goods for road/rail/air/sea transport
Packing Group: Not assigned
Special Precautions for User: Avoid dust generation, keep in original packaging, protect from moisture

Regulatory Information

Label Requirements: Product label should indicate proper handling and safety instructions
Agency Listing: Not subject to specific regulations in most countries, but nutritional ingredients should comply with relevant pharmacopeia and food safety standards
Safety Assessment: SDS and product details must comply with national chemical safety frameworks (e.g., OSHA in U.S., REACH in Europe)
Other Regulatory Status: Consider relevant worker protection and environmental laws when handling in bulk or disposing of surplus