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Product Name: Reserpine
Chemical Formula: C33H40N2O9
Synonyms: Raudixin, Serpasil, Indian snakeroot alkaloid
CAS Number: 50-55-5
Manufacturer: [Manufacturer's information]
Emergency Phone Number: [Emergency contact information]
Intended Use: Pharmaceutical, research, lab reagent
GHS Classification: Acute Toxicity (Oral) Category 3, Reproductive Toxicity Category 2, Specific Target Organ Toxicity (Repeated Exposure) Category 2
Label Elements: Skull and crossbones, Exclamation mark, Health hazard
Hazard Statements: Toxic if swallowed, Suspected of damaging fertility or the unborn child, May cause damage to organs through prolonged or repeated exposure
Precautionary Statements: Wear protective gloves, Avoid breathing dust, Wash hands thoroughly after handling
Health Effects: Headache, fainting, mental depression, nasal congestion, gastric upset
Environmental Hazards: Harmful to aquatic life with long lasting effects
Chemical Name: Reserpine
Concentration: ≥97% (purity may vary by supplier)
Molecular Weight: 608.7 g/mol
Impurities: Minor plant alkaloids, solvent traces from extraction
Additives: None (unless specified by supplier)
Inhalation: Move affected person to fresh air, monitor for respiratory distress, provide oxygen if breathing becomes labored, seek medical treatment immediately
Skin Contact: Immediately remove contaminated clothing, rinse skin thoroughly with soap and water for at least 15 minutes, consult a doctor
Eye Contact: Rinse carefully with plenty of clean, lukewarm water for at least 15 minutes, lift eyelids occasionally, seek immediate medical attention
Ingestion: Do not induce vomiting, rinse mouth with water, administer water if conscious, seek prompt medical evaluation, provide details of material to medical personnel
Symptoms and Effects: May cause low blood pressure, bradycardia, tremors, abnormal muscle movements, and mental depression
Note to Physicians: Treat symptomatically, monitor cardiovascular and nervous system function
Suitable Extinguishing Media: Water spray, CO2, dry chemical powder, foam
Unsuitable Extinguishing Media: Strong water jets may scatter powder
Specific Hazards from Combustion: Emits toxic fumes of nitrogen oxides and carbon oxides when heated to decomposition
Protective Equipment: Use self-contained breathing apparatus and full protective clothing in case of fire
Firefighting Instructions: Keep containers cool with water spray, prevent run-off from entering drains or watercourses
Personal Precautions: Evacuate area, ensure adequate ventilation, use personal protective equipment including gloves, goggles, and approved respirator
Environmental Precautions: Prevent further leakage, spill, or release into soil, drains, or water sources
Cleanup Methods: Absorb spills with inert materials such as sand or vermiculite, place waste in suitable containers for proper disposal, decontaminate area thoroughly with soap and water
Emergency Procedures: Report spill to appropriate emergency response authorities and supervisor, restrict access until cleanup is complete
Precautions for Safe Handling: Handle in a fume hood or well-ventilated area, avoid contact with skin and eyes, prevent dust formation, use correct PPE
Hygiene Measures: Do not eat, drink, or smoke during handling, wash hands and exposed skin before breaks and after work
Storage Conditions: Keep container tightly closed, store in a cool, dry location, shield from light, keep away from incompatible substances such as strong acids or bases
Packaging Materials: Store in amber glass or high-density polyethylene containers with tamper-evident seals
Incompatibilities: Oxidizers, strong acids, and bases
Exposure Limits: No established occupational exposure limits; minimize exposure as a precaution
Engineering Controls: Use only with adequate local exhaust ventilation, work in fume hood if possible
Personal Protective Equipment: Chemical-resistant gloves (nitrile recommended), safety goggles, laboratory coat, NIOSH-approved respiratory protection where risk of airborne dust or insufficient ventilation exists
Environmental Controls: Prevent material from reaching sewers or natural water surfaces
Other Precautions: Keep inaccessible to untrained personnel, have emergency shower and eyewash stations available
Appearance: White to pale yellow crystalline powder
Odor: Practically odorless
pH: Not applicable (non-aqueous solid)
Melting Point: 266 - 267°C
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water, freely soluble in alcohol, chloroform; sparingly soluble in ether
Density: Approximately 1.34 g/cm³
Partition Coefficient (log Kow): 3.0
Vapor Pressure: Negligible at room temperature
Chemical Stability: Stable under recommended storage and handling conditions
Decomposition Products: Hazardous gases including nitrogen oxides and carbon monoxide may form upon heating
Conditions to Avoid: Extreme heat, strong light, moisture
Incompatible Materials: Strong oxidizers, acids, bases
Polymerization: Does not polymerize
Acute Toxicity: Oral LD50 (rat) approximately 50 mg/kg
Target Organs: Nervous system, cardiovascular system
Health Hazards: Toxic if ingested, may cause hypotension, sedation, depression, nasal congestion, and disorders of cardiac rhythm
Chronic Effects: Possible risk of depression, gastrointestinal disturbances, and reproductive toxicity with prolonged exposure
Carcinogenicity: Not evaluated for carcinogenic potential in humans by IARC, NTP, or OSHA
Reproductive Toxicity: Evidence suggests risk to fetal development with repeated exposure
Sensitization: Not classified as a sensitizer
Other Information: Use strict laboratory safety controls to minimize risk
Ecotoxicity: Harmful to aquatic life, can contribute to long-lasting adverse effects in the aquatic environment
Aquatic Toxicity: LC50 (fish) data not thoroughly established, but likely in low mg/L range based on structural analogues
Persistence and Degradability: Moderately persistent, limited biodegradability
Bioaccumulative Potential: Potential for bioaccumulation in aquatic and terrestrial organisms
Mobility in Soil: Low to moderate mobility expected based on partition coefficient
Other Adverse Effects: Spills and improper disposal may disrupt local ecosystems
Waste Treatment Methods: Dispose according to local, regional, and national regulations for hazardous chemical waste
Product Disposal: Incinerate under controlled conditions or use approved chemical waste disposal company
Packaging Disposal: Decontaminate containers if possible, otherwise treat as hazardous waste
Precautions: Do not dispose into environment, drains, or watercourses
Contaminated Materials: Collect and incinerate contaminated gloves, cloths, or other exposables
UN Number: UN2811
Proper Shipping Name: Toxic solid, organic, n.o.s. (Reserpine)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Special Precautions: Ship only in approved packaging, ensure labeling as toxic hazard, maintain documentation for emergency response
Environmental Hazards: Marine pollutant
Transport Regulations: Adhere to road (ADR), air (IATA), and marine (IMDG) codes
Inventory Listings: Listed on major chemical inventories (TSCA, EINECS/ELINCS)
Labelling: Subject to hazard communication requirements for toxic substances
Workplace Safety Regulations: Controlled substance under select regulations in certain regions, consult local guidelines
OSHA Hazard Classification: Toxic material, reproductive hazard
Other Applicable Laws: Requires permits and registration for pharmaceutical manufacturing, specific controls based on country
International Agreements: Subject to transport and handling standards under global treaties on hazardous substances
