© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Substance Name: (R)-4-Benzyl-2-Oxazolidinone
Synonyms: (R)-4-Benzyl-2-oxazolidone; Chiral Auxiliary
CAS Number: 82544-97-6
EC Number: 617-277-8
Recommended Uses: Intermediate in organic synthesis, pharmaceutical research, custom chemical synthesis
Manufacturer: Provided by laboratory supply companies in bulk or sample quantities for research
Contact Information: Laboratory supplier’s customer support, available on the package or accompanying paperwork
Emergency Phone Number: Referenced from local supplier or national emergency chemical number
GHS Classification: Not classified as hazardous by GHS criteria, but precaution is standard in lab settings
Signal Word: None required under typical handling conditions
Hazard Statements: May cause mild skin or eye irritation; inhalation of dust should be avoided
Precautionary Statements: Wear protective gloves, eye protection, and avoid generating dust
Symbol(s): No pictograms required under GHS for standard laboratory use, but professional handling advised
Routes of Exposure: Skin and eye contact, inhalation of dust, incidental ingestion
Potential Health Effects: Repeated exposure may cause dryness or cracking of the skin; eyes may become irritated upon direct contact
Chemical Name: (R)-4-Benzyl-2-Oxazolidinone
Concentration: >99% (in most laboratory settings)
Impurities: Typically less than 1% trace organic impurities from synthesis processes
Molecular Formula: C10H11NO2
Molecular Weight: 177.20 g/mol
Physical Form: Solid crystalline powder, white to off-white
Other Components: No significant additives or stabilizers in standard reagent grade
Skin Contact: Wash thoroughly with soap and water; remove contaminated clothing
Eye Contact: Rinse cautiously for several minutes, lift eyelids to ensure thorough rinsing; seek medical attention if discomfort persists
Inhalation: Move to fresh air and keep at rest in a comfortable position; seek medical care if symptoms like coughing or shortness of breath develop
Ingestion: Rinse mouth out and obtain medical advice if feeling unwell or after swallowing large amounts
Most Important Symptoms: Redness or irritation of eyes and skin; cough after inhaling dust
Notes for Physicians: Treat symptoms; no specific antidote known
Suitable Extinguishing Media: Dry chemical, CO2, foam or water spray
Specific Hazards: May emit nitrogen oxides, carbon monoxide and carbon dioxide under fire conditions
Protective Equipment for Firefighters: Full protective gear and self-contained breathing apparatus advised
Special Procedures: Contain runoff to prevent environmental contamination; avoid raising dust; use water spray to cool unopened containers
Explosion Data: Non-explosive under normal use, but dust can mingle with air and combust if ignition source present
Personal Precautions: Use gloves, safety goggles and dust mask; ventilate area before cleaning
Environmental Precautions: Prevent entry into drains, sewers or waterways; sweep or vacuum without stirring up dust
Cleanup Methods: Collect spilled material mechanically, deposit in a sealed waste container; wash down remaining traces with water
Disposal: Store in appropriate container for transfer to authorized chemical waste facility
Precautions for Safe Handling: Wear gloves, laboratory coat, and eye protection; avoid breathing dust; handle in a well-ventilated fume hood if possible
Hygiene Measures: Wash hands and face thoroughly after handling; keep work spaces clean
Storage Conditions: Store in tightly closed, properly labeled container; keep in a dry, cool, and well-ventilated place away from incompatible materials like strong oxidizers
Incompatibilities: Strong acids, bases, oxidizing agents
Storage Class: General chemical storage
Occupational Exposure Limits: No established exposure limit values for this compound
Engineering Controls: Use in a chemical fume hood; utilize dust collection for bulk handling
Personal Protection: Safety glasses with side shields, chemical-resistant gloves (nitrile recommended), laboratory coat; dust mask or respirator for dusty operations
Environmental Controls: Use procedures to prevent dispersal and inhalation of dust; ensure effluent is filtered or contained
Appearance: Solid, white to off-white crystalline powder
Odor: Odorless or faint organic scent
Odor Threshold: Not applicable
pH: Not applicable in solid form
Melting Point: 95-99°C
Boiling Point: Decomposes prior to boiling
Flash Point: Not determined
Evaporation Rate: Not applicable
Flammability: Not classified as highly flammable; dust can support combustion
Vapor Pressure: Negligible at room temperature
Vapor Density: Not applicable
Water Solubility: Slightly soluble
Partition Coefficient (n-octanol/water): Not established
Auto-ignition Temperature: Not determined
Decomposition Temperature: Not established; avoid overheating
Viscosity: Not applicable in solid state
Chemical Stability: Stable under normal laboratory conditions; avoid moisture
Conditions to Avoid: High temperatures, exposure to open flames, contact with strong oxidizers
Materials to Avoid: Strong acids, bases, and oxidizing substances
Hazardous Decomposition Products: Nitrogen oxides, carbon monoxide, carbon dioxide
Polymerization: Will not occur under recommended handling
Acute Toxicity: Information not fully available; low toxicity expected based on structure and similar compounds
Inhalation: Dust may cause mild irritation to respiratory tract
Skin Contact: Prolonged or repeated contact may cause mild irritation or dryness
Eye Contact: Solid may cause irritation, redness, lacrimation
Ingestion: Large quantities may produce gastrointestinal upset; no chronic adverse effects reported
Chronic Toxicity: Data lacking for chronic exposure; good laboratory practice and engineering controls provide protection
Sensitization: No known effects for standard laboratory use; prolonged contact could sensitize susceptible individuals
Carcinogenicity: Not classified as carcinogenic under current regulations
Mutagenicity: No gene mutation data available for compound; low risk inferred from structure
Reproductive Toxicity: No data available
Ecotoxicity: No detailed studies on aquatic or terrestrial organisms; low expected toxicity but avoid uncontrolled release
Persistence and Degradability: Likely to degrade slowly in environment due to stable oxazolidinone ring
Bioaccumulative Potential: Structure suggests low likelihood of bioaccumulation
Mobility in Soil: Restricted; solid tends to remain near spill site
Other Adverse Effects: Not expected to impact environment severely at laboratory scale
Waste Disposal Methods: Collect as chemical waste and dispose in accordance with local, national, and regional regulations; incineration or chemical landfill typically recommended
Container Disposal: Decontaminate empty containers before recycling or disposal; puncture and triple rinse if permitted
Special Precautions: Do not allow material to enter water supplies or sewer systems; advisories change regionally based on chemical regulations
UN Number: Not classified as hazardous for transport
Proper Shipping Name: (R)-4-Benzyl-2-Oxazolidinone or laboratory chemical, not regulated
Transport Hazard Classes: Not assigned; ship as non-dangerous material
Packing Group: Not regulated
Environmental Hazards: Not considered a marine pollutant
Special Precautions for Users: Transport in well-sealed, labeled containers; protect from mechanical damage and moisture during shipment
Safety, Health and Environmental Regulations: No specific regulatory reporting requirements under REACH, TSCA, or comparable regional lists for standard research use
Inventory Status: Not listed as a controlled chemical in principal regulatory inventories
Labeling Requirements: Label in line with laboratory and workplace safety standards—chemical name, supplier, hazard, and precautionary statements
Other Information: Not regulated as a pesticide, medical drug or explosive; further guidance found in local chemical hygiene plan; lab personnel expected to comply with institutional training and PPE standards
