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Material Safety Data Sheet for Quinocetone

1. Identification

Product Name: Quinocetone
Chemical Formula: C13H10N2O2S
CAS Number: 81810-66-4
Synonyms: 3-Methyl-2-quinoxalin-2-yl-1,4-benzoquinone
Recommended Use: Veterinary medicine, feed additive (not approved in all countries)
Manufacturer Details: Name, address, emergency contact number provided by supplier
Emergency Phone Number: Provided by manufacturer or local poison control

2. Hazard Identification

Classification: Eye irritation (Category 2), Skin sensitization (Category 1), Specific target organ toxicity (Category 2)
Label Elements: Warning, hazard pictograms for irritation and sensitization
Hazard Statements: May cause skin and eye irritation. Suspected of causing genetic defects. Harmful if swallowed or inhaled.
Precautionary Statements: Wear protective gloves, avoid breathing dust, wash hands thoroughly after use, use only outdoors or in a well-ventilated area.
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Health Effects: Possible respiratory tract irritation, skin rash, eye redness, systemic effects after prolonged exposure
Environmental Hazards: Harmful to aquatic life with long lasting effects

3. Composition / Information on Ingredients

Chemical Name: Quinocetone
CAS Number: 81810-66-4
Concentration: 97-100% Quinocetone
Impurities: Trace organic compounds or additives, less than 3%
Other Additives: None stated for pure product

4. First Aid Measures

Inhalation: Move affected person to fresh air. Support breathing if required. Seek medical attention.
Eye Contact: Rinse gently with water for several minutes. Remove contact lenses if present. Continue rinsing. Get medical advice if irritation persists.
Skin Contact: Remove contaminated clothing. Rinse skin with plenty of water. Seek medical help if rash or irritation develops.
Ingestion: Rinse mouth with water. Do not induce vomiting without guidance from medical personnel. Call poison center or get medical attention immediately.
Most Important Symptoms: Coughing, sneezing, sore throat, skin redness, eye discomfort, abdominal pain after ingestion
Notes for Doctor: Treat symptomatically. Monitor for allergic reactions or respiratory distress.

5. Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, dry chemical, foam, carbon dioxide
Special Hazards: Produces hazardous gases such as nitrogen oxides and sulfur oxides during combustion
Protective Equipment: Self-contained breathing apparatus, complete protective clothing
Specific Fire Fighting Procedures: Prevent fire-fighting run-off from entering waterways. Use caution as containers may rupture under intense heat.
Explosion Data: No explosive properties identified, but fine dust may form combustible mixtures with air

6. Accidental Release Measures

Personal Precautions: Evacuate unnecessary personnel. Wear appropriate protective equipment. Avoid dust formation.
Environmental Precautions: Prevent product from entering drains, sewers, or watercourses. Notify environmental authorities in the event of a large spill.
Containment and Cleanup: Sweep up and place in suitable closed container for disposal. Use damp methods or approved vacuum cleaner to minimize dust.
Decontamination: Wash spill area with water and detergent. Ensure proper ventilation.
Disposal: Dispose of in compliance with local regulations.

7. Handling and Storage

Handling: Avoid breathing dust. Avoid contact with skin, eyes, and clothing. Use personal protective equipment. Ensure adequate ventilation. Do not eat, drink, or smoke while handling.
Storage: Store in a tightly closed container. Keep in cool, dry, well-ventilated place away from direct sunlight and incompatible materials.
Incompatible Substances: Strong oxidizers, acids, alkalis
Storage Temperature: Store at room temperature, protect from freezing and excessive heat
Special Packaging Requirements: Use containers resistant to chemical action of product

8. Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation. Maintain workplace air levels below occupational exposure limits.
Personal Protective Equipment: - Respiratory: Use NIOSH-approved dust respirators if dust is generated - Hands: Chemical-resistant gloves - Eye: Safety glasses with side shields - Skin/Body: Lab coat or full protective clothing
Environmental Protection: Control emissions to prevent release to environment

9. Physical and Chemical Properties

Appearance: Yellow to orange crystalline powder
Odor: Slight, not distinctive
Odor Threshold: Not established
pH (solution): Not determined
Melting Point: 188-190°C
Boiling Point: Not established (decomposes before boiling)
Flash Point: Not established
Evaporation Rate: Not applicable (solid)
Flammability: Not flammable, but dust may combust
Vapor Pressure: Negligible at room temperature
Solubility in water: Low (insoluble to sparingly soluble)
Solubility in other solvents: Slightly soluble in organic solvents
Partition Coefficient (log Kow): Not available
Vapor Density: Not applicable
Relative Density: Approximately 1.4 g/cm³
Other Information: Stable under recommended storage and handling conditions

10. Stability and Reactivity

Chemical Stability: Stable under normal conditions.
Reactivity: Not highly reactive under typical conditions.
Possible Hazardous Reactions: May react with strong oxidizing agents.
Incompatible Materials: Strong acids, oxidizers, alkalis
Decomposition Products: Toxic or irritating fumes including nitrogen oxides, sulfur oxides, carbon monoxide, carbon dioxide
Conditions to Avoid: Heat, direct sunlight, moisture, static discharge

11. Toxicological Information

Acute Toxicity: Oral LD50 (rat) > 2,000 mg/kg.
Skin Corrosion/Irritation: May cause mild to moderate irritation with prolonged exposure.
Serious Eye Damage: Causes eye irritation.
Respiratory Sensitization: Dust inhalation may provoke respiratory irritation.
Skin Sensitization: May cause allergic skin reactions.
Germ Cell Mutagenicity: Animal studies suggest possible mutagenic potential.
Carcinogenicity: Not classified by IARC, NTP, OSHA.
Reproductive Toxicity: No definitive data.
STOT-single exposure: May cause transient respiratory or mucous membrane irritation.
STOT-repeated exposure: Target organ effects not fully characterized.
Other Effects: Allergic dermatitis, photosensitivity possible in sensitive individuals

12. Ecological Information

Toxicity to Aquatic Organisms: Harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Persistence and Degradability: Not readily biodegradable.
Bioaccumulative Potential: Data lacking; limited evidence of significant bioaccumulation.
Mobility in Soil: Low water solubility, expected to adsorb to soil particles.
Other Adverse Effects: Avoid release to environment.
Large Releases: Reportable to appropriate authorities in many jurisdictions

13. Disposal Considerations

Product Disposal: Dispose of as hazardous waste following national, state, and local regulations. Incineration or professional hazardous waste disposal recommended.
Container Disposal: Empty containers may contain hazardous residues. Rinse and dispose in accordance with regulations.
Methods of Disposal: Avoid release to waterways. Do not dispose of with household refuse.
Contaminated Packaging: Treat as hazardous waste.
Precautions: Do not attempt disposal without proper authorization; improper handling could contaminate soil or water.

14. Transport Information

UN Number: Not classified as a hazardous material for transport.
Proper Shipping Name: Quinocetone, chemical
Transport Hazard Class: Non-regulated for road, rail, sea, or air
Packing Group: Not assigned
Environmental Hazards: Avoid accidental release during transit; harmful to water systems.
Transport Precautions: Packages should be secure, sealed, and properly labeled.
Special Provisions: Comply with national and international regulations for chemical transport

15. Regulatory Information

International Regulations: Not listed on major international hazardous substance lists.
United States: Not subject to specific SARA Title III or TSCA reporting; check state lists.
European Union: Not registered under REACH, not on Annex XIV or SVHC; use limitations apply for animal feed.
Japan: Not under PRTR Law; may appear on local inventory lists.
China: Agricultural and feed use restricted or prohibited.
Occupational Exposure Limits: No established ACGIH, OSHA, or EU OEL.
Other National Regulations: Consult local chemical safety agencies for requirements specific to your area.
Labeling Requirements: Hazard and precautionary statements should appear on containers.
Worker Protection: Employer responsible for appropriate safety practices based on national law and guidance