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Material Safety Data Sheet: Pyridoxal Hydrochloride

Identification

Product Name: Pyridoxal Hydrochloride
Chemical Formula: C8H10ClNO3
Synonyms: Pyridoxal HCl, Vitamin B6 hydrochloride
CAS Number: 41447-08-3
Recommended Use: Laboratory reagent, pharmaceutical intermediate, food supplement component
Supplier Details: Manufacturer’s name, full address, phone number of emergency contact

Hazard Identification

Classification: Not classified as hazardous under GHS or OSHA criteria
Health Hazards: Mild irritation to eyes, slight skin discomfort, may cause gastrointestinal upset if ingested
Environmental Hazards: Data indicates low risk to aquatic organisms
Signal Word: None
Pictograms: No hazard pictograms required
Potential Routes of Exposure: Inhalation, ingestion, skin, and eye contact
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, use with adequate ventilation

Composition / Information on Ingredients

Chemical Identity: Pyridoxal Hydrochloride
Concentration: ≥98%
CAS Number: 41447-08-3
Impurities and Stabilizing Additives: Trace inorganic salts, no ingredients identified as hazardous above regulatory thresholds

First Aid Measures

Inhalation: Move to fresh air, seek medical attention if symptoms persist
Skin Contact: Remove contaminated clothing, immediately wash with soap and plenty of water, seek medical advice for irritation
Eye Contact: Flush eyes with clean water for at least 15 minutes, remove contact lenses if present, consult a physician
Ingestion: Rinse mouth, drink water to dilute, never give anything by mouth to an unconscious person, contact physician if feeling unwell
Most Important Symptoms: Eye, mucous membrane irritation, mild GI disturbance possible after ingestion

Fire-Fighting Measures

Extinguishing Media: Use water spray, carbon dioxide, dry chemical powder, or suitable foam
Non-Suitable Media: Direct water jet for large fires
Hazardous Combustion Products: Nitrogen oxides, hydrochloric acid, carbon monoxide, carbon dioxide
Protective Equipment: Firefighters wear self-contained breathing apparatus and full protective gear
Advice for Firefighters: Cool containers exposed to fire with water spray, control run-off to prevent entry into waterways

Accidental Release Measures

Personal Precautions: Avoid breathing dust, prevent skin and eye contact, ensure adequate ventilation
Protective Equipment: Respirator, chemical-resistant gloves, safety goggles, laboratory coat
Containment: Sweep up material, avoid creating airborne dust, place into suitable container for disposal
Cleanup Procedures: Wash spill area with detergent and water, ventilate area, collect contaminated wash waters for disposal
Environmental Precautions: Prevent entry into drains, surface waters, soil

Handling and Storage

Safe Handling: Handle in a well-ventilated area, minimize dust generation and accumulation, do not eat or drink while using
Hygiene Measures: Wash hands and face after handling, do not touch eyes or face with contaminated gloves
Storage Conditions: Keep container tightly closed, store at room temperature (15-25°C), avoid moisture and direct sunlight
Incompatibilities: Strong oxidizers, strong acids, strong bases, reactive metals
Container Requirements: Use corrosion-resistant, airtight containers; label containers clearly

Exposure Controls and Personal Protection

Occupational Exposure Limits: No specific exposure limits established
Engineering Controls: Use fume hood or local exhaust, eyewash stations, safety showers
Personal Protection – Eyes: Safety goggles
Personal Protection – Skin: Chemical-resistant gloves and protective lab clothing
Personal Protection – Respiratory: Use dust respirator if dust formation likely
Environmental Exposure: Implement measures to prevent product release to environment

Physical and Chemical Properties

Appearance: White to yellowish crystalline powder
Odor: Odorless or slight characteristic smell
Odor Threshold: Not established
pH: 2.0 - 3.0 (1% solution in water)
Melting Point: 162-166°C (decomposes)
Boiling Point: Not applicable (decomposes)
Flash Point: Data not available
Flammability: Not classified as flammable
Vapor Pressure: Not applicable
Solubility: Soluble in water, slightly soluble in ethanol, insoluble in ether
Partition Coefficient (log Kow): Data not available
Evaporation Rate: No data
Density: 1.41 g/mL
Other Properties: Stable, crystalline, hygroscopic

Stability and Reactivity

Chemical Stability: Stable under recommended conditions, sensitive to light and moisture
Reactivity: No violent reactions under normal conditions
Conditions to Avoid: Exposure to excessive heat, open flames, incompatible chemicals, humidity
Materials to Avoid: Strong oxidizers, strong acids, strong bases
Hazardous Decomposition: Nitrogen oxides, carbon monoxide, carbon dioxide, hydrogen chloride
Polymerization: Will not occur under normal storage and handling

Toxicological Information

Routes of Exposure: Eye, skin, ingestion, inhalation
Acute Toxicity: Estimated oral LD50 (rat) > 2,000 mg/kg
Irritation: Mild eye, skin and respiratory irritation possible
Sensitization: Not reported
Chronic Effects: No data linking substance to reproductive toxicity, carcinogenicity, mutagenicity
Medical Conditions Aggravated: Preexisting eye, skin, respiratory conditions
Symptoms of Overexposure: Headache, nausea, mild gastrointestinal upset

Ecological Information

Ecotoxicity: Expected to have minimal toxicity to aquatic life
Persistence and Degradability: Biodegradable in soil and water
Bioaccumulative Potential: Low potential for bioaccumulation
Mobility in Soil: High mobility due to water solubility
Other Adverse Effects: No known significant environmental hazards at relevant concentrations

Disposal Considerations

Waste Disposal: Bury in approved landfill or send to authorized waste treatment facility; avoid release to sewage or natural waters
Container Disposal: Triple rinse, puncture and dispose in accordance with local, regional, national regulations
Precautions: Do not incinerate closed containers, keep waste away from heat, sparks, open flame

Transport Information

UN Number: Not applicable
Proper Shipping Name: Not regulated
Transport Hazard Class: None
Packing Group: None
Environmental Hazards: Not a marine pollutant
Special Precautions: Avoid mechanical shock, keep containers upright and secure during transport

Regulatory Information

OSHA Status: Not regulated as hazardous
TSCA: Listed on TSCA inventory
SARA Title III: Not subject to reporting
DSL/NDSL (Canada): Listed
EU Classification: Not classified as hazardous under CLP Regulation (EC) No 1272/2008
Labeling Requirements: Standard chemical labeling, hazard communication as good laboratory practice demands
Other Regulations: Users must follow local, state, and federal laws dealing with chemicals and hazardous materials