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Product Name: Pralidoxime Iodide
Synonyms: 2-Pyridinealdoxime methiodide; 2-PAM iodide
CAS Number: 5070-10-6
Molecular Formula: C7H9IN2O
Molecular Weight: 264.07 g/mol
Recommended Use: Management of organophosphate poisoning, antidote
Supplier Information: Contact details of chemical provider or distributor, including address, phone number, and emergency contact.
Emergency Phone Number: Emergency contact line for chemical spills or exposure available with supplier documentation.
Classification: Acute toxicity (oral, dermal, inhalation), eye irritation, skin irritation
GHS Label Elements: Danger
Hazard Statements: Harmful if swallowed, causes severe eye irritation, may cause skin and respiratory tract irritation, toxic to aquatic life with long lasting effects.
Precautionary Statements: Avoid breathing dust or vapors, wash face and hands after handling, wear suitable gloves and eye/face protection, prevent release to the environment.
Routes of Exposure: Inhalation, skin contact, ingestion, eye contact
Main Symptoms: Nausea, headache, muscular weakness, increased heart rate, blurred vision, convulsions may occur in cases of severe poisoning.
Target Organs: Nervous system, cardiovascular system
NFPA Ratings: Health: 2; Flammability: 0; Reactivity: 0.
Chemical Identity: Pralidoxime Iodide
Concentration: >98%
Impurities/Stabilizing Additives: Trace amounts of hydrazine may be present, along with water or moisture content less than 1%.
Ingredient CAS#: 5070-10-6
Inhalation: Move exposed person to fresh air, keep at rest, seek medical attention if symptoms persist.
Skin Contact: Remove contaminated clothing, rinse skin thoroughly with soap and water for at least 15 minutes, seek medical advice for signs of irritation.
Eye Contact: Flush eyes with gently running water for at least 15 minutes, lift eyelids, remove contact lenses if present, immediate medical attention required.
Ingestion: Rinse mouth with water, never induce vomiting, seek medical help immediately, do not give anything by mouth to an unconscious person.
Most Important Symptoms/Effects: Overstimulation of muscles, dizziness, possible convulsions or respiratory depression in severe cases.
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide to extinguish fire.
Unsuitable Media: Do not use water jet on burning material.
Specific Hazards: Decomposition can release toxic fumes such as nitrogen oxides, iodine compounds, and carbon oxides.
Protective Equipment for Firefighters: Wear self-contained breathing apparatus, full protective clothing.
Specific Methods: Remove all persons from fire area, stay upwind, control firefighting runoff to avoid environmental contamination.
Personal Precautions: Use personal protective equipment including gloves, safety goggles, lab coat or chemical apron, dust respirator as required.
Environmental Precautions: Prevent further leakage or spillage if safe, avoid entry into drains, surface water, or soil to minimize environmental impact.
Methods for Cleaning Up: Sweep up using inert absorbent material, place in labeled chemical waste container, ventilate affected area, wash site with water.
Disposal of Contaminated Material: Collect and dispose of all residues and clean-up materials according to local regulatory requirements.
Handling: Avoid creating dust, use only in well-ventilated areas, keep containers sealed when not in use, never eat, drink or smoke around the chemical, handle with care to avoid splashes or spills.
Storage Conditions: Store at room temperature (15-25°C) away from incompatible substances such as strong acids, bases, oxidizing agents, and sunlight. Keep container tightly closed in a dry, cool, and well-ventilated place.
Incompatible Materials: Strong acids, strong bases, strong oxidizing agents
Other Precautions: Store out of reach of unauthorized individuals, label all containers with content and hazard information.
Exposure Limits: No occupational exposure limits established, limit exposure by administrative and engineering controls.
Engineering Controls: Use chemical fume hood, local exhaust system, and adequate general ventilation.
Personal Protective Equipment: Protective gloves (nitrile or neoprene), laboratory apron or lab coat, chemical safety goggles with side shields, respiratory protection if dust formation possible.
Hygiene Measures: Wash hands and face before breaks and after handling, remove and wash contaminated clothing before reuse.
Environmental Controls: Prevent chemical from entering drains or waterways, keep work area clean, implement spill containment as required.
Appearance: White to off-white crystalline powder
Odor: Odorless
Odor Threshold: Not applicable
pH: 4.2 – 6.2 (50 mg/ml aqueous solution)
Melting Point/Freezing Point: 230°C (decomposes)
Boiling Point and Range: Not applicable (decomposes before boiling)
Flash Point: Non-flammable
Evaporation Rate: Not applicable
Flammability: Not flammable under standard conditions
Vapor Pressure: Negligible at ambient temperature
Vapor Density: Not applicable
Relative Density: 1.69 g/cm³
Solubility: Soluble in water, slightly soluble in ethanol
Partition Coefficient (n-octanol/water): Not available
Auto-ignition Temperature: Not self-igniting
Decomposition Temperature: >230°C
Viscosity: Not applicable
Other Data: Stable under standard conditions, can form dusts which may be hazardous if inhaled.
Chemical Stability: Stable under recommended storage conditions, moisture-sensitive
Possibility of Hazardous Reactions: May react violently with strong oxidants, releases toxic fumes in thermal decomposition
Conditions to Avoid: Heat, flames, sparks, moisture, and direct sunlight
Incompatible Materials: Strong oxidizing agents, strong acids, strong bases
Hazardous Decomposition Products: Nitrogen oxides, iodine vapors, carbon oxides
Polymerization: Will not occur under normal handling and storage.
Acute Toxicity: Oral LD50 (rat): approximately 230 mg/kg; may vary with source and formulation
Routes of Exposure: Signs and symptoms may arise from ingestion, inhalation, skin or eye contact
Symptoms: Muscle twitching, headache, nausea, respiratory depression, irregular heartbeat, hypotension, increased secretion production
Chronic Effects: Long-term exposure may affect nervous system, possible liver and kidney impairment documented in rare cases
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA
Mutagenicity/Teratogenicity: No evidence in standard animal assays
Other Data: Individuals with hypersensitivity may exhibit allergic reactions or increased sensitivity; prolonged or repeated exposure should be avoided.
Ecotoxicity: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Expected to degrade slowly; persistence in soil and water may result in buildup of toxic residues
Bioaccumulative Potential: Low bioaccumulation potential, not lipid-soluble
Mobility in Soil: Highly soluble in water; may migrate through soil to contaminate groundwater if released
Other Adverse Effects: Avoid environmental release; not considered to be an ozone-depleting chemical but can affect non-target species.
Waste Treatment Methods: Incinerate in a chemical incinerator equipped with afterburner and scrubber as per national and local regulations
Additional Information: Dispose of unused product, contaminated packaging, and waste in accordance with local, regional, and national regulations, do not discharge to sewers or natural water bodies
Contaminated Packaging: Triple rinse before disposal, offer rinsate to appropriate disposal facility, puncture and render packaging unusable.
UN Number: Consult shipping documentation for proper UN identification
UN Proper Shipping Name: Toxic solid, organic, n.o.s. (contains Pralidoxime iodide)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Marine Pollutant: Yes, avoid exposure to the marine environment
Transport Labels: Toxic substance label
Special Precautions for User: Handle and transport in accordance with local, regional, and international regulations, prevent spillage during transport.
Regulatory Status: Regulated as a hazardous chemical under OSHA Hazard Communication Standard (29 CFR 1910.1200)
TSCA Inventory: Listed
REACH Registration: Subject to registration for import into the European Union
SARA Title III: Not subject to specific reporting requirements but categorized under hazardous substances
WHMIS Classification (Canada): D2B (Toxic Material Causing Other Toxic Effects)
California Proposition 65: Not listed as a known carcinogen or reproductive toxicant
Other relevant national/international regulations: Conforms to IATA, IMDG, DOT requirements for toxic solids; manufacturer or supplier provides up-to-date regulatory references.
