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Chemical: Potassium O-Nitrophenoxide
Common Use: Intermediate in organic synthesis, research reagent
Appearance: Pale yellow crystalline solid or powder
Odor: Faint, chemical-like
Solubility: Soluble in water and organic solvents like ethanol
Molecular Formula: C6H4KNO3
CAS Number: Not commonly listed in public databases, often classified as laboratory-only chemical
Hazard Class: Oxidizer, irritant
Acute Hazards: Eye and skin irritation, respiratory issues upon inhalation
Chronic Hazards: Possible effects on blood and kidneys with repeated or prolonged exposure
Pictograms: Corrosive and exclamation mark symbols, reflecting its irritant and harmful nature
GHS Label Elements: Signal word “Warning”, notices regarding skin, eye, and respiratory irritation
Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Main Ingredient: Potassium O-Nitrophenoxide (greater than 98%)
Impurities: Possible trace organic residues from synthesis, typically not considered hazardous in small quantities but relevant for purity-sensitive applications
Additives: None typically added; stored in pure solid form for laboratory work
Eye Contact: Flush immediately with plenty of water for at least 15 minutes; seek medical attention
Skin Contact: Remove contaminated clothing, wash affected area with soap and water; call for medical help if irritation continues
Inhalation: Move to fresh air immediately; apply artificial respiration if not breathing; seek urgent care
Ingestion: Do not induce vomiting; rinse mouth thoroughly with water; get medical attention as soon as possible
Special Notes: Always bring MSDS information and sample if medical assistance is required, as healthcare staff benefit from having this context
Suitable Extinguishing Media: Use dry chemical powder, foam, or CO2 extinguisher; water spray for small fires only
Specific Hazards: Thermal decomposition sends off toxic fumes, including nitrogen oxides and potassium compounds
Protective Equipment: Standard firefighting turnout gear plus self-contained breathing apparatus
Advice for Firefighters: Avoid breathing vapors and keep containers cool with water mist from distance to reduce risk of explosion due to pressure build-up
Combustion Products: Nitrogen oxides, potassium oxides
Personal Precautions: Use gloves, goggles, lab coat, and NIOSH-approved respirator if dust is generated
Environmental Precautions: Prevent runoff into sewers or waterways; avoid contamination of soil and vegetation
Small Spills: Sweep up carefully in a way that avoids dust, collect in a sealed container; ventilate area
Large Spills: Evacuate area, notify safety personnel, use appropriate containment measures, absorb residues with inert material
Clean-up Procedures: Wash down surfaces with plenty of water after physical removal; ensure site is completely decontaminated before restarting operations
Handling: Use in well-ventilated area or fume hood; avoid breathing in dust or vapors, avoid contact with eyes and skin, never eat/drink/smoke around open containers
Storage: Keep locked up, away from acids, reducing agents, and combustible materials; store in tightly closed containers in a cool, dry space
Incompatibilities: Strong acids, reducing agents, combustible organics
Protection from Physical Damage: Containers need secondary containment to avoid spills from breaks or accidental dropping
Engineering Controls: Fume hoods, local exhaust ventilation, unbreakable containers
Personal Protective Equipment: Chemical-resistant gloves (preferably nitrile), safety goggles, lab coat, face shield for large-scale transfers
Respiratory Protection: NIOSH-approved particulate respirator for handling powders or working outside proper ventilation
Hygiene Measures: Wash hands/face thoroughly after handling, shower before leaving lab or worksite
Occupational Exposure Limit: No specific regulatory limit, but always minimize exposure by adhering to good chemical hygiene practices
Form: Crystalline solid, fine powder
Color: Pale to bright yellow
Odor: Faintly pungent, chemical
Melting Point: Estimated between 110°C - 130°C (sample-dependent due to purity variance)
Solubility: Readily soluble in water and alcohols; moderate solubility in organic solvents like DMSO
pH: Slightly basic (alkaline) in aqueous solution
Vapor Pressure: Negligible at room temperature
Stability: Stable under normal storage and handling conditions
Reactive Hazards: May react vigorously with acids, reducing agents, or strong oxidizers
Hazardous Decomposition: Nitrogen oxides and potassium oxide fumes if heated strongly or burned
Polymerization: Does not polymerize
Conditions to Avoid: Exposure to moisture, high heat, sources of ignition, incompatible chemicals
Acute Toxicity: Can cause moderate irritation to eyes, skin, and respiratory tract; some animal studies suggest mild to moderate systemic toxicity on ingestion
Chronic Effects: Repeated exposure raises risk of kidney and blood function disruption
Carcinogenicity: No available evidence for human carcinogenicity, not listed with IARC or NTP
Sensitization: Risk of contact sensitization possible with repeated handling
Symptoms: Redness, soreness, coughing, shortness of breath, nausea after substantial exposure
Aquatic Toxicity: Likely hazardous to aquatic life based on nitrophenolic structure, which can persist in water and harm fish and other organisms
Terrestrial Impact: Mobility in soil can lead to groundwater contamination; nitro compounds often slow to degrade
Persistence and Degradability: Not easily broken down in the environment, tends to accumulate
Bioaccumulation: Potential for buildup in ecosystems, especially aquatic ones
Precautions: Waste minimization and responsible disposal help reduce long-term environmental impact
Recommended Methods: Treat as hazardous laboratory waste, segregate from household trash, use qualified waste disposal company
Neutralization: Chemical neutralization possible under controlled conditions, but only in equipped facilities
Contaminated Packaging: Dispose of empty containers as hazardous waste, do not reuse for other chemicals or household use
Legal Requirements: Follow local and federal rules for handling and disposal, as improper dumping can bring heavy penalties
Transport Hazards: Considered hazardous for transport; informs labeling, packaging, and paperwork
Transport Recommendation: Ship in well-sealed, impact-resistant containers, avoid mixing with incompatible goods, clearly mark with hazard symbols
Prohibited Modes: Certain forms may be restricted via air or sea freight given their oxidizing and irritant properties
Regulation: No broad commercial regulations due to limited volume and lab research focus, but often falls under Controlled Substances or Hazardous Chemicals classification for transport and handling
Workplace Law: Subject to OSHA laboratory safety standards and chemical hygiene plans where used in the United States
Environmental Law: Subject to EPA rules for hazardous waste and water discharge when used at significant scale
Labeling: GHS and local WHMIS/CLP labeling mandates clear identification and hazard communication
