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Product Name: Polysorbate 20
Other Names: Polyoxyethylene (20) sorbitan monolaurate, Tween 20
CAS Number: 9005-64-5
Recommended Use: Nonionic surfactant for pharmaceuticals, food, cosmetics, laboratory reagents
Supplier: Contact details as provided by manufacturer or distributor
Emergency Contact: Local poison control or supplier emergency line
Classification: Not classified as hazardous according to GHS criteria
Physical Hazards: Slippery when spilled, slight risk of static accumulation
Health Hazards: Prolonged skin or eye contact may cause mild irritation, ingestion can cause gastrointestinal discomfort
Environmental Hazards: May cause minor effects on aquatic organisms if released in large quantities
Signal Word: None required
Pictogram: Not applicable
Chemical Name: Polysorbate 20
Common Name: Tween 20
Component: Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivatives
CAS Number: 9005-64-5
Purity: >99%
Inhalation: Move person to fresh air, monitor for respiratory symptoms; seek medical advice if coughing or shortness of breath persists
Eye Contact: Rinse gently with water for several minutes; remove contact lenses, continue rinsing; have medical professional examine for persistent discomfort
Skin Contact: Remove contaminated clothing, wash exposed area with soap and water; seek medical attention for irritation
Ingestion: Rinse mouth thoroughly, drink water for dilution; do not induce vomiting; consult healthcare provider in case of adverse effects or continued discomfort
Suitable Extinguishing Media: Water spray, foam, dry chemical, carbon dioxide
Unsuitable Media: Direct stream of water can spread material
Hazards from Combustion: Can produce fumes, carbon monoxide, carbon dioxide under high heat
Special Protective Equipment: Full protective clothing and respiratory protection for firefighters; avoid inhaling fumes
Specific Procedures: Cool containers exposed to fire with water spray; prevent runoff from entering drains or water sources
Personal Precautions: Wear gloves, goggles, protective clothing; keep unnecessary personnel away
Spill Clean-Up: Soak up with inert absorbent material (sand, earth); collect in containers for disposal
Environmental Precautions: Prevent runoff to drains, surface waters
Method for Disposal: Sweep or scoop solid; absorb liquid with materials; ventilate area well
Handling: Use with proper ventilation, avoid inhaling mist or vapors, avoid contact with skin and eyes; wash hands thoroughly after use
Storage: Store in tightly sealed containers in a cool, dry, well-ventilated place; keep away from incompatible substances like strong oxidizers
Incompatibilities: Strong acids, alkalis, and oxidizing agents
Recommended Container Materials: High-quality HDPE, stainless steel, or glass
Workplace Exposure Limits: No established exposure limits for Polysorbate 20
Engineering Controls: Use local exhaust ventilation to minimize exposure
Personal Protective Equipment: Safety glasses or goggles, impervious gloves (nitrile, butyl rubber), lab coat or apron, use face shield for high-splash risk
Respiratory Protection: Not normally required, but approved mask or respirator in poorly ventilated areas
Hygiene Practices: Wash hands and face after handling, do not eat or drink in working area
Appearance: Clear to slightly yellow, viscous liquid
Odor: Faint, characteristic
Melting Point: Approximately -5°C
Boiling Point: Above 100°C
Flash Point: >100°C (Closed cup)
Solubility: Soluble in water, ethanol
Specific Gravity: About 1.08 – 1.10 (water = 1, 20°C)
pH (solution): 5.0 – 7.0
Viscosity: High
Vapor Pressure: Negligible at ambient conditions
Chemical Stability: Stable under normal conditions, no hazardous polymerization
Reactivity: Not reactive with most substances
Hazardous Decomposition: Carbon oxides under fire or excessive heat
Conditions to Avoid: Excessive heat, open flames
Incompatible Materials: Strong oxidizing agents, strong acids and alkalis
Acute Toxicity: Low; high doses may cause diarrhea or nausea if ingested
Skin Irritation: Minor irritation possible on prolonged or repeated contact
Eye Irritation: Slight temporary discomfort or redness
Respiratory Sensitization: Not expected to cause sensitization
Carcinogenicity: Not classified as carcinogen, not listed by IARC, NTP, OSHA
Chronic Effects: No known long-term health effects in typical workplace exposures
Ecotoxicity: Not toxic to aquatic life in low concentrations; large releases may affect water quality
Persistence and Degradability: Readily biodegradable in standard tests
Bioaccumulation: Does not bioaccumulate in organisms
Mobility in Soil: High water solubility; moves easily in water
Other Adverse Effects: None known in typical uses
Waste Disposal Methods: Dispose according to local, state, federal regulations; incineration or sanitary landfill preferred
Unused Product: Send to authorized chemical disposal contractor
Contaminated Packaging: Rinse thoroughly, recycle or dispose according to regulations
Special Precautions: Prevent disposal to natural waters and storm drains whenever possible
UN Number: Not regulated as dangerous good
Proper Shipping Name: Not regulated
Transport Hazard Class: Not applicable
Packing Group: Not applicable
Special Precautions for Transport: Keep container tightly sealed and upright during transport to prevent leakage
US Regulations: Listed on TSCA inventory; not classified as hazardous under OSHA
EU Regulations: Listed under EINECS/ELINCS; not considered a hazardous substance
Canadian Regulations: Listed on DSL/NDSL
International Inventories: Compliant with regulations in Japan, Australia, Korea, China
Labeling Requirements: No special labeling required beyond good industrial hygiene and safety practice
