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Product Name: Policresulen
Chemical Formula: C24H16O7S2
Synonyms: 4,4'-dihydroxy-3,3'-sulfonyl-biphenyl-formaldehyde condensation product, Hemoclair, Albothyl
CAS Number: 135-62-6
Intended Use: Used as a topical antiseptic and hemostatic agent in medical settings, usually applied to mucous membranes
Manufacturer’s Contact: Detailed information provided by supplier upon request
Emergency Contact: Refer to local poison control center or emergency health services
Product Form: Solid (powder) or aqueous solution
Relevant Identified Uses: Medical, dental, and veterinary topical applications
GHS Classification: Skin Corrosion/Irritation: Category 2; Serious Eye Damage/Eye Irritation: Category 2A
Signal Word: Warning
Hazard Statements: Causes skin irritation, may cause eye irritation, harmful if swallowed
Pictograms: Exclamation mark
Route of Exposure: Skin, eyes, ingestion
Target Organs: Mucous membranes, skin, eye tissues
Principal Hazards: Strong acidic irritant, can cause burns and tissue damage, especially with prolonged exposure
Precautionary Statements: Wear protective gloves, wash hands thoroughly, avoid inhalation and direct contact
Other Hazards: Not classified as carcinogenic or mutagenic under current regulations
Main Ingredient: Policresulen (approx. 98%)
Chemical Structure: Condensation product of meta-cresolsulfonic acid and formaldehyde
Impurities: Trace amounts of formaldehyde, meta-cresol derivatives, water (in solutions), excipients
Concentration Range: Varies by formulation; typically between 5% (solution) to 98% (powder)
Additives: Stabilizers and preservatives in aqueous formulations, such as sodium chloride or sodium sulfate
Component Contribution: Policresulen delivers antimicrobial and hemostatic effects, other components provide physical stability
Regulatory Listings: All main components appear in relevant chemical inventories for international trade
Inhalation: Move person to fresh air, seek medical attention for persistent symptoms such as coughing or difficulty breathing
Skin Contact: Immediately remove contaminated clothing, wash affected area thoroughly with soap and water, seek medical advice for persistent irritation
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, seek immediate medical attention
Ingestion: Do not induce vomiting, rinse mouth with water, seek medical attention quickly
Note to Physicians: Treat symptomatically, monitor for gastrointestinal burns and respiratory distress in severe cases
Special Instructions: Always bring product label or container if seeking medical help
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry powder, foam
Unsuitable Media: Do not use high-pressure water jets that may spread the substance
Special Hazards: Combustion releases sulfur dioxide, carbon monoxide, carbon dioxide, and possibly formaldehyde fumes
Protective Equipment: Wear self-contained breathing apparatus, full protective suit
Specific Procedures: Remove containers from fire area if safely possible
Fire Residue Disposal: Collect contaminated firefighting water and dispose according to regulations
Personal Precautions: Use chemical-resistant gloves, protective eyewear, suitable footwear, and face protection
Environmental Precautions: Prevent further leakage or spillage if safe to do so, avoid entry into waterways, drains, or soil
Containment Methods: Confine spill area, cover with inert absorbent material such as sand or soil
Cleanup Procedures: Collect absorbed material in approved waste containers, wash spill site after cleanup
Reporting Spills: Notify relevant safety authorities if required by law
Decontamination: Clean affected surfaces thoroughly, check area for residue before resuming normal operations
Handling Precautions: Avoid direct contact, use only with sufficient ventilation, do not eat or drink near product, avoid generating dust or aerosols
Safe Storage Conditions: Keep containers tightly sealed in a cool, dry, well-ventilated place, store away from acids and alkalis
Incompatible Materials: Strong oxidizers, reducing agents, acids, bases
Safe Transfer: Use proper dispensing equipment, minimize splashing
Sectioned Storage: Store separately from food and feedstuffs
Labeling: Maintain clear, legible labels on all containers
Occupational Exposure Limits: No established TLV or OEL for Policresulen; limit exposure to lowest feasible
Engineering Controls: Use local exhaust ventilation, eye wash stations, emergency showers
Personal Protective Equipment: Chemical-resistant gloves, lab coats or aprons, goggles or face shields, suitable footwear
Hygiene Measures: Wash thoroughly after handling, remove contaminated clothing before leaving work area
Respiratory Protection: Wear a P2/P3 particulate mask under dust-forming conditions
Exposure Monitoring: Routine air monitoring not required under normal use; special situations may need assessment
Appearance: White to off-white crystalline powder or clear, colorless to yellowish aqueous solution
Odor: Slight, phenolic or medicinal
Molecular Weight: 480.5 g/mol
pH (solution): 0.5 - 2.0 (high acidity in solution form)
Melting Point: Above 200°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Readily soluble in water, partially soluble in alcohol
Viscosity: Low-moderate (aqueous solution)
Density: 1.6 g/cm³ (approx.)
Partition Coefficient: Not determined
Vapor Pressure: Negligible at room temperature
Explosive Properties: Not classified as explosive
Flammability: Not a flammable solid
Chemical Stability: Stable under recommended storage conditions
Reactivity: Reacts with strong bases and oxidizing agents
Hazardous Reactions: May release formaldehyde or sulfur oxides upon contact with strong acids, bases, or during combustion
Decomposition Products: Carbon monoxide, carbon dioxide, sulfur oxides, formaldehyde
Conditions to Avoid: Avoid exposure to heat, flames, strong acids, alkalis
Polymerization: Does not undergo hazardous polymerization
Acute Toxicity: LD50 (oral, rat) >5,000 mg/kg
Skin Irritation: Causes irritation, possible burns with direct contact or prolonged exposure
Eye Irritation: Causes severe irritation, possible corneal injury
Inhalation Risk: Low due to low volatility, inhalation of dust may cause respiratory irritation
Chronic Effects: No evidence of carcinogenicity or mutagenicity in standard testing
Allergic Reactions: Not a known sensitizer
Medical Conditions Aggravated by Exposure: Skin disorders, respiratory issues may worsen with exposure
Symptoms of Overexposure: Redness, soreness, ulceration at contact site, headache, nausea if ingested
Ecotoxicity: Harmful to aquatic organisms, especially at high concentrations
Persistence and Degradability: Limited data; chemical structure may resist rapid biological degradation
Bioaccumulative Potential: Not expected to accumulate significantly in aquatic life
Mobility in Soil: High solubility in water increases mobility; may reach groundwater
Other Adverse Effects: Spills contribute to local acidity, can harm soil microorganisms
Precautions for Environment: Avoid discharge into the environment; use safe disposal practices
Waste Treatment Methods: Collect as hazardous chemical waste
Product Disposal: Incinerate with proper emission controls or use chemical treatment facilities authorized for acidic organic chemicals
Container Disposal: Rinse thoroughly before recycling or dispose in accordance with regional guidelines
Special Disposal Measures: Do not release into drains, watercourses, or soil
Local Regulations: Follow instructions from local environmental protection authorities
Recommended Disposal Code: Seek category classification under hazardous waste regulations, typically as organic acid or pharmaceutical waste
UN Number: Not classified under UN Dangerous Goods Regulations
Proper Shipping Name: Not regulated for transport as a hazardous material
Transport Hazard Class: None assigned
Packing Group: None assigned
Environmental Hazards: Not a marine pollutant
Special Precautions: Do not transport with food or food containers, keep container tightly closed during transport
Regulatory Guidance: Observe local and national transport regulations for corrosive substances if classified for specific formulations
Labelling Requirements: Labels must carry product name, hazards, manufacturer, lot number, precautionary measures
SARA Title III: Not listed specifically
TSCA Inventory: Not separately listed but components covered
REACH Status: Subject to registration requirements within the EU
OSHA Status: Not regulated as a hazardous chemical under OSHA
WHMIS Classification: May fall under D2B (toxic material causing other effects) in Canada
Other National Regulations: Observe local workplace safety and health, environmental regulations, and pharmaceutical guidelines for topical agents
