© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: Piperazine Citrate
Synonyms: Piperazine hexahydrate citrate, 1,4-diazacyclohexane citrate
Chemical Formula: C4H10N2·C6H8O7
CAS Number: 41372-12-1
Intended Use: Anthelmintic agent in pharmaceutical formulations, included in veterinary and human medicine for treatment of parasitic infections
Supplier Details: Manufacturer name, address, emergency contact information
Recommended Use Restrictions: Provided for professional and industrial use only, not for home or recreational use or in uncontrolled environments
Classification: Not classified as hazardous under GHS; low acute toxicity
Hazard Statements: Avoid contact with eyes, skin, prolonged inhalation
Precautionary Statements: Use personal protective equipment as appropriate, wash skin thoroughly after handling, avoid breathing dust
Potential Health Effects: Inhalation may irritate respiratory tract, ingestion in large amounts can cause gastrointestinal upset or neurological symptoms, skin or eye contact may cause mild irritation
Signal Word: None required
Pictograms: None assigned
Other Hazards: Dust generation can present risk of mild respiratory irritation, no known chronic health hazards in normal handling
Chemical Name: Piperazine Citrate
Concentration: 100%
CAS Number: 41372-12-1
Impurities: No relevant impurities negatively affecting classification disclosed by suppliers
Additives: None contemplated in standard pharmaceutical or laboratory grade material
Inhalation: Remove affected person to fresh air, provide supportive medical attention if symptoms occur
Skin Contact: Rinse thoroughly with soap and water for several minutes, remove contaminated clothing
Eye Contact: Rinse cautiously with water for several minutes, lift upper and lower eyelids occasionally, seek care if irritation persists
Ingestion: Rinse mouth with water, seek medical advice if large amounts are swallowed or symptoms present
General Notes: No delayed effects known, no antidote required, symptomatic treatment provides control over mild exposure
Suitable Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or alcohol-resistant foam
Specific Hazards: Non-combustible, can emit toxic fumes, including nitrogen oxides and carbon oxides, under fire conditions
Special Protective Equipment: Firefighters require self-contained breathing apparatus and protective clothing
Hazardous Combustion Products: Carbon monoxide, carbon dioxide, nitrogen oxides can form at high heat
Special Procedures: Avoid inhaling dust or fumes, keep material out of confined or poorly ventilated spaces
Personal Precautions: Use personal protective equipment, prevent generation of dust, ventilate closed spaces before entry
Environmental Precautions: Prevent product from entering drains, sewers, and surface water
Containment: Sweep up and shovel material, place in suitable, closed containers for disposal
Cleanup Methods: Clean with water and detergent, avoid creating airborne dust during collection
Other Advice: Dispose of waste via authorized sites, follow all local, state, and national regulations
Safe Handling: Avoid inhalation and contact with skin and eyes, handle in well-ventilated area, wear appropriate protective equipment
Hygiene Measures: Wash hands thoroughly after handling, do not eat or drink in areas where material is used
Storage Conditions: Store in tightly closed containers, keep in a cool, dry, well-ventilated area, protect against direct sunlight and moisture
Incompatible Materials: Strong oxidizers, acids, and bases can cause hazardous reactions or degradation
Packaging: Use corrosion-resistant and airtight containers to prevent absorption of atmospheric moisture
Exposure Limits: No occupational exposure limit values established for piperazine citrate
Engineering Controls: Employ general room ventilation, local exhaust recommended for large-scale use
Personal Protection – Eye: Use safety glasses or chemical splash goggles
Personal Protection – Skin: Wear impervious gloves, lab coats or coveralls
Personal Protection – Respiratory: Use dust mask or respirator in case of inadequate ventilation or high dust concentrations
Workplace Hygiene: Routine hand washing after handling
Appearance: White or off-white crystalline powder
Odor: Odorless
pH: Approximately 5-7 (aqueous solution)
Melting Point: Decomposes before melting
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water
Density: No data available
Vapor Pressure: Not relevant
Flash Point: Not flammable
Partition Coefficient: No data available
Explosive Properties: Not explosive
Oxidizing Properties: Not an oxidizer
Chemical Stability: Stable under normal temperatures and pressures
Reactivity: No strong reactivity under expected use conditions
Hazardous Reactions: Strong oxidizing substances may lead to hazardous decomposition
Conditions to Avoid: Excessive heat, moisture, open flames
Incompatible Materials: Oxidizers, acids, and alkalis
Hazardous Decomposition: Produces carbon dioxide, carbon monoxide, nitrogen oxides under fire or high temperature
Acute Toxicity: Low toxicity by oral, dermal, or inhalation routes
Symptoms of Exposure: Gastrointestinal disturbance (nausea, vomiting, diarrhea), possible mild central nervous system effects in high doses
Skin/Eye Irritation: Mild irritation possible
Sensitization: Rare, but some allergic skin reactions reported
Chronic Toxicity: No evidence of carcinogenicity, mutagenicity, or reproductive toxicity
Relevant Studies: Toxicological studies in animals show low systemic toxicity at therapeutic levels
Ecotoxicity: Low environmental hazard, not expected to bioaccumulate
Mobility: Moderately mobile in soil, soluble in water
Degradability: Biodegradable under environmental conditions
Bioaccumulation Potential: Does not persist or build up in aquatic environments
Other Adverse Effects: No significant effect on aquatic organisms at low concentrations based on available data
Waste Disposal Method: Dispose in accordance with local, state, and federal regulations, do not discharge to drains or environment
Container Disposal: Use puncture-proof, closed containers for any waste; decontaminate or incinerate in approved facility
Special Considerations: Do not reuse emptied containers without proper cleaning
UN Number: Not regulated as dangerous good
Proper Shipping Name: Not restricted
Transport Hazard Class: Not applicable
Packing Group: Not assigned
Special Transport Precautions: Avoid exposure to moisture or extremes of heat during shipment, secure containers against spillage
TSCA (USA): Listed
DSL/NDSL (Canada): Listed
REACH (EU): Not classified as hazardous under EC Regulation 1272/2008
OSHA Hazard Communication: Not hazardous
Other Listings: No reporting requirements under SARA Title III, CERCLA, or RCRA
Labeling Requirements: Comply with all workplace, transportation, and pharmaceutical labeling regulations for safe use and handling
