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Material Safety Data Sheet (MSDS) for Picrorhiza Scrophulariiflora Extract

1. Identification

Product Name: Picrorhiza Scrophulariiflora Extract
Other Names: Kutki, Hu Huang Lian extract
Product Use: Herbal supplement, ingredient in traditional medicine, pharmaceutical research
Manufacturer/Distributor: Supplier contact information to be provided on the packaging
Emergency Contact: Local or national poison center, health and safety officer
Recommended Restrictions: Not intended for use except as directed in product literature or label

2. Hazard Identification

Classification: Not classified as a hazardous substance under most global regulations, but dust inhalation and skin/eye contact may cause minor irritation
Label Elements: No pictogram required, but precautionary statements about personal protective equipment can minimize risk
Signal Word: None required
Hazard Statement: Dust or powder may cause respiratory tract irritation, skin, and eye discomfort
Precautionary Statement: Avoid breathing dust, wash hands after handling, use in a well-ventilated area
Other Hazards: Not known to contain sensitizers, carcinogens, or mutagens at typical workplace concentrations

3. Composition / Information on Ingredients

Chemical Identity: Extract of Picrorhiza Scrophulariiflora root
Common Name: Kutki extract
CAS Number: Not specifically assigned; plant-derived mixture
Concentration: Potency and concentration depend on manufacturer’s extraction process but often standardized to 5-10% picrosides
Impurities: Possible trace contaminants from soil or extraction solvents within regulatory limits
Synonyms: Picrorhiza, Hu Huang Lian extract, Kutki root extract

4. First Aid Measures

Inhalation: Move to fresh air, monitor for persistent cough or breathing difficulty, consult a physician if irritation persists
Skin Contact: Wash thoroughly with soap and water, seek medical advice for persistent redness or sensitivity
Eye Contact: Rinse immediately with plenty of water, remove contact lenses, seek medical attention if irritation remains
Ingestion: Rinse mouth with water, do not induce vomiting, observe for gastrointestinal discomfort, consult medical personnel if symptoms occur
Notes for Medical Professionals: Treat symptomatically; no specific antidote identified for this botanical extract

5. Fire-Fighting Measures

Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide for surrounding fire
Specific Hazards: Organic powder may create a risk of dust explosion if dispersed in air and exposed to ignition source
Special Protective Equipment: Firefighters should wear self-contained breathing apparatus and full turnout gear
Combustion Products: Incomplete combustion can release carbon monoxide, carbon dioxide, and possibly other irritant gases
Advice for Firefighters: Avoid dust generation, avoid inhalation of smoke, use water spray to cool exposed containers

6. Accidental Release Measures

Personal Precautions: Use protective gloves, dust mask or respirator, and eye protection
Environmental Precautions: Prevent large spills from entering waterways or drains, dilute small quantities with ample water
Methods for Clean Up: Use damp absorbent material or a vacuum fitted with HEPA filter to collect spilled powder, dispose in accordance with local regulations
Reference to Other Sections: Refer to disposal considerations and personal protective equipment details below

7. Handling and Storage

Handling: Avoid raising dust, use in well-ventilated area, wear recommended personal protective gear, wash hands after handling
Storage: Keep container tightly closed, store in cool, dry place away from direct sunlight and moisture; avoid contact with incompatible substances such as strong oxidizers
Special Requirements: Clearly label containers, keep away from food and beverages, restrict access to authorized personnel

8. Exposure Controls and Personal Protection

Control Parameters: No occupational exposure limits established for picrosides; typical workplace controls for plant powders apply
Engineering Controls: Good general ventilation, local exhaust ventilation for bulk handling
Personal Protective Equipment: Protective gloves (nitrile or similar), safety goggles, N95 or equivalent dust mask for airborne powders, lab coat or coveralls
Hygiene Measures: Wash hands and face before eating, drinking, or smoking, keep contaminated work clothes separate

9. Physical and Chemical Properties

Appearance: Fine powder or coarse granule, light to dark brown
Odor: Mild, earthy, herbal
Odor Threshold: Not established
pH: Typically slightly acidic to neutral in water suspension
Melting Point/Freezing Point: Not applicable to mixture
Boiling Point / Range: Not applicable to botanical extract
Flash Point: Not established, but organic materials can support combustion
Evaporation Rate: Not available
Flammability: Can form combustible dust clouds
Vapor Pressure/Density: Not applicable
Solubility (Water): Partially soluble
Partition Coefficient (n-octanol/water): Not determined
Decomposition Temperature: Not precisely determined
Viscosity: Not applicable

10. Stability and Reactivity

Chemical Stability: Stable under recommended storage conditions
Reactivity: Not expected to react dangerously under normal handling
Incompatibility: Strong oxidizers and acids can degrade product or create hazardous conditions
Hazardous Decomposition: Possible emission of carbon monoxide, carbon dioxide, and organic irritants at high temperature
Hazardous Polymerization: Will not occur
Conditions to Avoid: Excess heat, moisture, direct sunlight, open flames, spark sources

11. Toxicological Information

Possible Routes of Exposure: Inhalation, skin contact, eye contact, ingestion
Acute Effects: May cause mild irritation to eyes, skin, or respiratory system; ingestion of large amounts may cause gastrointestinal upset
Chronic Effects: No known long-term hazards at typical workplace exposures; safety data limited by lack of large-scale studies
Sensitization: No evidence of significant skin or respiratory sensitization under intended use
Carcinogenicity: Not classified as carcinogenic; IARC, NTP, OSHA do not list picrosides as cancer hazard
Mutagenicity/Teratogenicity: No conclusive evidence for genotoxic or reproductive toxicity
Medical Conditions Aggravated by Exposure: Pre-existing respiratory issues may be irritated by dust exposure

12. Ecological Information

Ecotoxicity: No specific toxicity data on aquatic or terrestrial organisms; plant extract expected to exhibit low toxicity but large spills should be avoided
Persistence/Degradability: Natural organic material undergoes biodegradation in soil and water
Bioaccumulation Potential: No known potential for bioaccumulation in wildlife
Mobility: Partial solubility in water may allow some migration through soil and water pathways
Other Adverse Effects: No effects on ozone depletion or global warming understood from current data

13. Disposal Considerations

Waste Treatment Methods: Residual product may be disposed with regular waste if not contaminated with hazardous chemicals; large quantities or spill residues should be treated as organic waste and disposed according to local environmental regulations
Container Disposal: Empty containers should be triple rinsed, then recycled or discarded as non-hazardous material if permitted
Special Precautions: Prevent product from entering drains or waterways; consult local, regional, or national guidelines for appropriate handling of herbal and plant-based wastes

14. Transport Information

UN Number: Not classified as hazardous for transport
Proper Shipping Name: Picrorhiza Scrophulariiflora Extract
Transportation Hazard Class: Not regulated
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Transport Precautions: Use sealed packaging to avoid dust release and moisture exposure during transit

15. Regulatory Information

Regulatory Status: Not subject to special labeling or restrictions as a food- or pharma-grade botanical under most national chemical safety regulations
Relevant Regulations: Product aligns with REACH exempt substances, TSCA natural substance exemptions, and may fall under local herbal supplements rules
Chemical Safety Assessment: No chemical safety assessment required under available regulations for plant extracts
Workplace Classification: Not classified as hazardous chemical; standard health and safety workplace protections recommended
Labeling Requirements: Maintain labeling with batch number, manufacturer, date of manufacture, and safety guidance for user reference