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Product Name: Phosphatidylserine
Chemical Name: 1,2-diacyl-sn-glycero-3-phospho-L-serine
Synonyms: PS, Soybean phosphatidylserine
CAS Number: 51446-62-9
Recommended Uses: Nutritional supplement, research applications
Manufacturer/Supplier: Refer to product label for supplier details
Emergency Contact: Refer to supplier emergency number
Classification: Not classified as hazardous under GHS
Physical Hazards: Dust or powder may cause mild irritation to eyes or respiratory system
Health Hazards: May trigger mild irritation to skin, eyes, or digestive tract. Very high inhalation exposure to dust could irritate airways
Environmental Hazards: Low persistence in environment, not identified as harmful to aquatic or soil organisms
Label Elements: No mandatory symbols
Signal Word: None
Precautionary Statements: Avoid generating dust. Use common sense hygiene practices
Substance: Phosphatidylserine
Percentage: >90% (purified form); presence of minor fatty acids and supporting phospholipids
Impurities: May contain traces of lecithin, glycerylphosphates, minor plant phospholipids
Ingredient Details: Derived from plant (commonly soybean, sunflower) or synthetic pathways. No major toxic excipients present
Inhalation: Move to fresh air, rinse mouth if needed, consult health professional if discomfort remains
Skin Contact: Wash thoroughly with water using gentle soap. Remove contaminated clothing
Eye Contact: Rinse eyes gently for several minutes with water. See medical help if irritation builds
Ingestion: Rinse mouth, drink water, monitor for any signs of gastrointestinal discomfort. Seek care if large amounts consumed
General Advice: Show label and safety data to medical personnel during treatment
Suitable Extinguishing Media: Use water spray, carbon dioxide, dry chemical, foam
Unsuitable Media: High-pressure water jets can spread powders
Fire Hazards: Organic dust may ignite in strong ignition sources; possible risk for dust explosion
Protective Equipment: Wear self-contained breathing apparatus and protective gear
Decomposition: Exposes hazardous gases like carbon oxides, phosphorous oxides if fully combusted
Advice for Firefighters: Move containers away from fire area if safe to do so. Prevent entry of runoff into environment
Personal Precautions: Wear protective mask/gloves to avoid breathing dust or contacting skin/eyes
Environmental Precautions: Prevent uncontrolled entry into waterways or soil
Methods for Clean Up: Pick up material using clean, dry methods. Scoop up bulk and wipe area with damp cloth to avoid dust re-suspension. Place waste in approved container
Reference to Other Sections: For disposal and further personal protection, reference corresponding sections below
Safe Handling: Handle in well-ventilated spaces. Avoid creating airborne dust. No eating or drinking during use. Wash hands after contact
Storage Conditions: Store in tightly sealed container. Keep in dry, cool, shaded environment. Protect from excess heat and direct sunlight
Incompatibilities: Strong oxidizers, open flames, and direct contact with moisture
Packaging Materials: Use original packaging or non-reactive secondary containers
Occupational Exposure Limits: Not established for phosphatidylserine. General dust limits: 10 mg/m³ for total inhalable dust
Engineering Controls: Use exhaust ventilation or local extraction to limit dust concentration
Personal Protective Equipment:
— Eyes: Safety goggles
— Skin: Gloves and protective clothing
— Inhalation: Dust mask or particulate respirator if workplace dust exceeds limit
Hygiene Practices: Wash hands and exposed skin after handling. Regularly clean workspaces to avoid build-up
Appearance: Off-white to pale yellow powder or granular solid
Odor: Mild, slightly fatty
Odor Threshold: Not determined
Molecular Formula: C₁₃H₂₄NO₁₀P (varies with fatty acid composition)
Molecular Weight: Approx. 749 g/mol (soy-derived form)
pH: 6-8 (1% in water)
Melting Point/Freezing Point: 60–80°C (depends on purity and acyl chain)
Boiling Point/Range: Decomposes before boiling
Solubility: Insoluble in water, soluble in chloroform, ethyl alcohol
Vapor Pressure: Not applicable
Density: 1.03–1.08 g/cm³
Partition Coefficient: Log P ≈ 3–6 (approximate, depends on lipid chain)
Flash Point: >150°C (estimate)
Chemical Stability: Stable in dry, sealed conditions without strong light or heat
Reactivity: Non-reactive under regular conditions
Hazardous Reactions: May react with oxidizers or acids; produces phosphorous oxides on combustion
Conditions to Avoid: Excess heat, open flame, prolonged contact with moisture
Incompatible Materials: Strong acids, oxidizing agents
Hazardous Decomposition: Carbon oxides, nitrogen oxides, phosphorus compounds during fire or severe heating
Acute Toxicity: Oral LD50 in rats > 5,000 mg/kg (low toxicity)
Chronic Toxicity: No evidence of carcinogenic or mutagenic effects in animal studies
Skin Corrosion/Irritation: No significant irritation with short exposure
Serious Eye Damage/Irritation: Mild, transient irritation only
Respiratory Sensitization: High dust exposure could infrequently irritate sensitive airways
Ingestion Effects: Unlikely to cause harm at dietary or workplace exposure levels. Very large doses may disrupt digestion
Other Data: Not listed as reproductive toxin or teratogen
Medical Symptoms Aggravated by Exposure: Asthma, chronic lung conditions
Ecotoxicity: Not identified as hazardous to aquatic life or plants in available studies
Persistence/Degradability: Biodegradable; decomposes naturally to CO₂, water, basic nutrients
Bioaccumulative Potential: Minimal—integration into environmental lipid cycles without concentration
Mobility in Soil: Low–moderate due to fatty, insoluble nature. May bind to organic material
Other Adverse Effects: No ozone depletion, no significant contribution to eutrophication or persistent pollution
Waste Disposal: Treat as non-hazardous laboratory or food waste. Dispose according to local and national regulations
Container Handling: Rinse thoroughly before recycling or discarding. Do not dispose in household waste
Environmental Cautions: Avoid release of significant quantities into drains or open ground
UN Number: Not regulated
UN Proper Shipping Name: Phosphatidylserine, non-hazardous
Transport Hazard Classes: None
Packing Group: Not required
Marine Pollutant: No
Transport Precautions: Secure containers to prevent breakage or leaks. Prevent contact with moisture during long-haul transport
Global Inventories: Listed in some national chemical inventories where dietary ingredients are regulated
TSCA: Exempt or listed in US as food/nutrient substance
REACH: Not classified as hazardous; no specific restrictions or labeling beyond usual industrial standards
OSHA: No specific OSHA limit for phosphatidylserine
Other Legislation: Not regulated as a controlled substance in major jurisdictions. Use and labeling requirements depend on geographic region and product type
Regulatory Status: Considered safe for food/nutraceutical applications by regulatory authorities in Europe, North America, and Asia under typical use conditions
