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Material Safety Data Sheet: Phenylmercuric Acetate

Identification

Product Name: Phenylmercuric Acetate
Chemical Formula: C8H8HgO2
CAS Number: 62-38-4
Synonyms: PMA, Mercurem Phenylacetate
Recommended Use: Laboratory reagent, antifungal preservative
Manufacturer Information: [Fill with supplier details]
Emergency Contact: Local poison control center or chemical incident response

Hazard Identification

GHS Classification: Acute Toxicity (Oral) Category 2; Acute Toxicity (Dermal) Category 3; Acute Toxicity (Inhalation) Category 3; Aquatic Acute Category 1; Aquatic Chronic Category 1
Pictograms: Skull and crossbones, environment
Signal Word: Danger
Hazard Statements: Fatal if swallowed, toxic if inhaled, toxic in contact with skin, very toxic to aquatic life with long-lasting effects
Precautionary Statements: Avoid all unnecessary exposure. Do not breathe dust or vapors. Wash hands thoroughly after handling. Avoid release to the environment.
Routes of Exposure: Skin, eyes, inhalation, ingestion
Potential Health Effects: Neurotoxic effects, kidney damage, allergic skin reaction

Composition / Information on Ingredients

Chemical Name: Phenylmercuric Acetate
CAS Number: 62-38-4
Concentration: 98-100%
Impurities: May contain trace levels of related organomercury compounds
Molecular Weight: 336.75 g/mol

First Aid Measures

Eye Contact: Rinse promptly with water for at least 15 minutes. Remove contact lenses if present. Seek medical attention immediately.
Skin Contact: Remove contaminated clothing. Wash skin thoroughly with soap and water. Get medical help if irritation occurs.
Inhalation: Move person to fresh air. Administer artificial respiration if breathing stops. Seek immediate medical care.
Ingestion: Rinse mouth with water. Do not induce vomiting unless instructed by medical personnel. Get emergency medical assistance.
Symptoms: Nausea, headache, dizziness, tremors, difficulty breathing, rash, kidney damage

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, CO2, water spray, or foam. Do not use water jet.
Specific Hazards: Emits toxic fumes under fire, including mercury vapor, phenyl compounds, and carbon oxides. Fire run-off may contaminate water supply.
Protective Equipment for Firefighters: Full protective gear, self-contained breathing apparatus.
Advice for Firefighters: Control run-off water to prevent entry into soil, drains, or waterways. Remove containers if safe to do so.

Accidental Release Measures

Personal Precautions: Evacuate personnel to safe area. Prevent contact with skin and eyes. Use personal protective equipment.
Environmental Precautions: Prevent leak or spillage from entering drains, sewers, or waterways. Notify authorities if contamination has occurred.
Cleanup Methods: Absorb spillage with inert material (sand, earth). Collect in suitable, labeled chemical waste containers. Ventilate area. Decontaminate surfaces with sodium thiosulfate solution.
Specific Spill Response: Recommended use of mercury spill kit and appropriate PPE.

Handling and Storage

Safe Handling Advice: Avoid generation of dust or aerosols. Wear proper PPE at all times. Only handle in well-ventilated areas inside chemical fume hoods.
Storage Requirements: Store in tightly closed container, in dry place at room temperature. Keep away from incompatible substances like acids, strong oxidizers, ammonia, and sulfide compounds.
Special Practices: Keep away from food, drink, and animal feed. Wash hands thoroughly before breaks and after handling.
Packing Materials: Use corrosion-resistant and shatterproof containers.

Exposure Controls and Personal Protection

Occupational Exposure Limits: OSHA PEL: 0.01 mg/m³ (as Hg, skin); ACGIH TLV: 0.01 mg/m³ (as Hg, skin)
Engineering Controls: Chemical fume hood, proper ventilation, closed handling systems
Personal Protection:

  • Respiratory: NIOSH-approved full-face respirator for mercury vapor/dust
  • Skin: Chemical-resistant gloves (nitrile, neoprene), lab coat, full body protective clothing
  • Eye: Chemical safety goggles, face shield
  • Hygiene: Remove contaminated clothing immediately; do not eat, drink, or smoke during use

Physical and Chemical Properties

State: Solid
Appearance: White crystalline powder
Odor: Odorless
Melting Point: 174°C
Boiling Point: Decomposes before boiling
Solubility: Slightly soluble in water, soluble in ethanol, acetone
pH (solution): Around neutral
Vapor Pressure: Negligible
Density: 2.44 g/cm³
Flash Point: Not applicable
Autoignition Temperature: Not determined

Stability and Reactivity

Chemical Stability: Stable under proper storage conditions
Conditions to Avoid: Heat, flames, sparks, exposure to direct sunlight
Incompatible Materials: Strong acids, strong oxidizing agents, ammonia, sulfides, active metals
Decomposition Products: Mercury vapors, phenyl compounds, carbon oxides
Hazardous Polymerization: Does not occur

Toxicological Information

Routes of Exposure: Ingestion, skin, inhalation, eyes
Acute Toxicity: Oral LD50 (rat): 15 mg/kg; Dermal LD50 (rabbit): not available; Inhalation LC50: data not available
Chronic Health Effects: Prolonged exposure may cause neurological damage, kidney damage, birth defects, and reproductive toxicity
Specific Symptoms: Headache, nausea, trembling, vision changes, dermatitis, renal dysfunction
Carcinogenicity: Not listed by IARC, NTP, or OSHA
Teratogenicity/Mutagenicity: Evidence of reproductive effects in animal studies

Ecological Information

Aquatic Toxicity: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Persistence and Degradability: Poorly biodegradable, persistent in the environment
Bioaccumulative Potential: Strong tendency to bioaccumulate in aquatic organisms
Mobility in Soil: May leach into groundwater, contaminating water sources
Other Effects: Environmental mercury cycling can magnify toxicity up the food chain

Disposal Considerations

Disposal Methods: Chemical waste collection by licensed disposal contractor. Do not dispose of with regular garbage.
Container Disposal: Triple rinse containers before disposal, then puncture and send for hazardous waste landfill.
Environmental Precautions: Prevent disposal in drains, surface, or ground water.
Relevant Regulations: Follow EPA, local, and state hazardous waste requirements.

Transport Information

UN Number: UN1673
UN Proper Shipping Name: Phenylmercuric Acetate
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: II
Marine Pollutant: Yes
Special Transport Precautions: Secure packaging, avoid vibration, appropriate hazard labels

Regulatory Information

TSCA Inventory: Listed
SARA Title III: Section 313 Toxic Chemical
CERCLA Reportable Quantity: 1 lb (Mercury compounds)
OSHA: Regulated as hazardous chemical
DSL/NDSL: Listed in Canadian inventory
EU Classification: T+ (Very toxic), N (Dangerous for the environment)
Restrictions: Subject to special requirements for environmental safety and disposal