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Product Name: Pepsin 1:3000
Chemical Family: Enzymes
Chemical Name: Pepsin
Synonyms: Protease, Acid Protease
Recommended Use: Laboratory reagent, food processing additive
CAS Number: 9001-75-6
EC Number: 232-629-3
Manufacturer: [Company Name]
Emergency Contact: [Phone Number]
GHS Classification: Respiratory Sensitizer (Category 1), Skin Sensitizer (Category 1)
Signal Word: Warning
Hazard Statements: May cause allergic skin reaction, may cause allergy or asthma symptoms or breathing difficulties if inhaled
Pictograms: Exclamation Mark, Health Hazard
Precautionary Statements: Avoid breathing dust, wear protective gloves/eye protection/face protection, use only outdoors or in a well-ventilated area
Substance: Pepsin
CAS Number: 9001-75-6
EC Number: 232-629-3
Concentration: 100% enzymatic protein (variable activity)
Additional Information: Contains no other hazardous ingredients above cutoff values according to current regulations
Inhalation: Move person to fresh air, seek medical help if asthma-like symptoms develop; administer oxygen if breathing is difficult
Skin Contact: Wash off with soap and plenty of water, remove contaminated clothing, seek medical advice if irritation or allergic reaction occurs
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing and seek medical attention
Ingestion: Rinse mouth, do not induce vomiting, seek medical attention if symptoms occur or if large amounts are swallowed
Most Important Symptoms and Effects: Allergic reactions such as respiratory discomfort, dermatitis, sensitization
Notes to Physician: Treat symptomatically, consider risks of asthma and allergic responses
Extinguishing Media: Use water spray, alcohol-resistant foam, dry chemical, or carbon dioxide
Hazards from Combustion: Thermal decomposition can produce carbon oxides, nitrogen oxides, and sulfur oxides
Protective Equipment for Firefighters: Wear self-contained breathing apparatus and full protective clothing
Specific Methods: Approach fire upwind to avoid hazardous vapors, avoid breathing fumes
Special Precautions: Dust from the product can form explosive mixtures with air, minimize dust generation
Personal Precautions: Evacuate personnel to safe areas, wear respiratory protection, avoid formation or inhalation of dust
Environmental Precautions: Do not let product enter drains or watercourses
Methods for Cleaning Up: Sweep up and shovel gently to avoid raising dust, keep in suitable, closed containers for disposal
Reference to Other Sections: Wear appropriate protective equipment as described in Section 8
Handling: Keep containers tightly closed, handle in well-ventilated areas, wear appropriate personal protective equipment, wash hands thoroughly after handling, avoid contact with skin, eyes, and clothing, prevent formation of dust
Storage: Store in cool, dry, and well-ventilated area, protect from moisture, store in original container, keep away from strong acids and alkalis, segregate from food and feedstuffs, keep out of reach of children
Incompatibilities: Strong oxidizing agents, strong bases, strong acids
Occupational Exposure Limits: No specific exposure limit established for pepsin, use general dust limits (e.g., 10 mg/m³ total dust, 5 mg/m³ respirable)
Engineering Controls: Provide local exhaust ventilation to minimize dust exposure
Personal Protective Equipment:
Gloves (chemical-resistant, such as neoprene or nitrile), goggles or safety glasses, lab coat or protective clothing, suitable respirator if dust is generated
Hygiene Measures: No eating, drinking, or smoking in work area, wash thoroughly after handling, launder contaminated clothing before reuse
Appearance: Off-white to light tan powder
Odor: Mild, characteristic
pH: 1.0 – 3.0 (1% solution)
Boiling Point: Not applicable
Melting Point: Not determined
Solubility in Water: Soluble
Flash Point: Not flammable
Flammability: Non-flammable but dust may form explosive mixtures
Vapor Pressure: Not applicable
Vapor Density: Not applicable
Relative Density: Not determined
Partition Coefficient (n-octanol/water): Not determined
Explosive Properties: Dusts can present explosion risk if dispersed in air
Chemical Stability: Stable under recommended conditions
Reactivity: No dangerous reactions known under normal conditions
Possibility of Hazardous Reactions: Contact with oxidizers, acids, or alkalis may result in denaturation or decomposition
Conditions to Avoid: Excessive heat, moisture, dust generation
Incompatible Materials: Strong oxidizing agents, acids, alkalis
Hazardous Decomposition Products: Carbon oxides, nitrogen oxides, sulfur oxides when heated to decomposition
Acute Toxicity (Oral, Dermal, Inhalation): Not expected to be acutely toxic in small quantities, inhalation of dust may lead to respiratory sensitization
Skin Corrosion/Irritation: May cause irritation, allergic skin reaction possible
Serious Eye Damage/Irritation: May cause eye irritation
Respiratory Sensitization: Sensitization possible with repeated inhalation
Skin Sensitization: Prolonged contact may cause allergic reactions
Chronic Toxicity: Repeated exposure can lead to asthmatic symptoms
Carcinogenicity: Not classified as carcinogenic by IARC, NTP, or OSHA
Mutagenicity: No data available indicating mutagenic effects
Reproductive Toxicity: No data available indicating reproductive toxicity
Ecotoxicity: Product is a protein, expected to degrade naturally; not anticipated to have significant adverse aquatic effects
Persistence and Degradability: Biodegradable enzyme
Bioaccumulative Potential: Low, based on protein structure
Mobility in Soil: Moderate solubility in water may permit movement in moist soil; enzymatic proteins generally bind to soil particles
Additional Information: Avoid large releases to aquatic environments, best practice to prevent product entering waterways or drains
Disposal Methods: Dispose of contents and container according to local, regional, national, and international regulations; use hazardous waste facility if required
Contaminated Packaging: Triple rinse containers and offer for recycling or disposal according to regulations
Precautions: Prevent material from entering drains or aquatic environments, avoid dust generation during handling and disposal
UN Number: Not regulated
Proper Shipping Name: Not regulated as a dangerous good
Transport Hazard Class: Not assigned
Packing Group: Not applicable
Marine Pollutant: No
Special Precautions for User: Avoid packaging damage, minimize dust formation during handling and transport
Labeling Requirements: Hazard pictograms required by GHS, statement on respiratory sensitization
Safety, Health, and Environmental Regulations: Listed under TSCA, EINECS, DSL, AICS, ENCS as a protein enzyme
SARA Title III Sections 311/312: Classified as an acute health hazard; respiratory and skin sensitizer
OSHA Hazards: Sensitizer
REACH Registration: Exempt as naturally occurring protein
Other Information: Handlers and users must review guidance supplied on SDS and comply with applicable local regulations
