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Product Name: Pargyline Hydrochloride
Chemical Name: N-Methyl-N-propargylbenzylamine hydrochloride
CAS Number: 555-57-7
Synonyms: Pargyline HCl
Recommended Use: Laboratory chemical, pharmaceutical research
Manufacturer: Supplier information available upon request
Emergency Contact: Refer to local regulations for poison control and emergency services
Hazard Classification: Acute oral toxicity (Category 4), Eye irritation (Category 2A), Skin irritation (Category 2)
Signal Word: Warning
Hazard Statements: Harmful if swallowed, causes skin and eye irritation, may affect organs through prolonged or repeated exposure
Pictograms: Exclamation mark
Precautionary Statements: Avoid inhalation, ingestion, or skin and eye contact; wash hands thoroughly after handling; do not eat, drink or smoke during use
Chemical Name: Pargyline Hydrochloride
CAS Number: 555-57-7
Formula: C11H13N·HCl
Concentration: 100% active material
Impurities: Not expected under normal usage; minor organic salts possible in trace amounts
Inhalation: Move exposed person to fresh air; keep at rest in a position that makes breathing easy; seek medical attention if symptoms develop
Skin Contact: Remove contaminated clothing; wash skin with soap and plenty of water for at least 15 minutes; get medical advice if irritation persists
Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present, continue rinsing, and seek medical attention
Ingestion: Rinse mouth with water, never induce vomiting unless directed by medical personnel, seek immediate medical help
Symptoms: Nausea, vomiting, headache, drowsiness, eye redness, skin irritation
Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical, carbon dioxide
Special Hazards: May release hazardous fumes such as nitrogen oxides, hydrogen chloride, carbon monoxide, and carbon dioxide in case of fire
Precautions for Firefighters: Wear self-contained breathing apparatus and full protective clothing
Specific Methods: Cool exposed containers with water spray to prevent rupture; evacuate area if fire occurs; contain run-off fire water to prevent environmental contamination
Personal Precautions: Wear chemical-resistant gloves, goggles, and laboratory coat; avoid breathing dust or vapor; provide adequate ventilation
Environmental Precautions: Prevent entry into waterways, drains, or soil; contain spill to prevent spread by covering with inert material
Methods for Cleanup: Sweep up and place in suitable closed container for disposal; wash contaminated surfaces with soap and water; ventilate area and dispose of wastes according to local regulations
Handling: Keep container tightly closed; minimize dust generation and accumulation; use only in well-ventilated areas; avoid all unnecessary exposure
Storage: Store in a cool, dry, and well-ventilated place; keep away from incompatible materials like strong oxidizing agents and strong acids; keep away from light and out of reach of unauthorized personnel; store in original packaging or sealed, clearly labeled containers
Exposure Limits: No occupational exposure limits established for this compound; avoid chronic exposure
Engineering Controls: Use local exhaust ventilation; utilize laboratory fume hood
Personal Protective Equipment: Safety goggles, chemical-resistant gloves (nitrile or neoprene preferred), lab coat or apron, respiratory protection if ventilation is inadequate
Hygiene Measures: Wash hands, forearms, and face thoroughly after handling; remove contaminated clothing and wash before reuse
Appearance: White to off-white crystalline powder
Odor: Odorless to faint amine-like
pH: Neutral to slightly acidic (in water)
Melting Point: 133-137°C
Boiling Point: Not applicable (decomposes)
Solubility: Soluble in water and ethanol
Density: Approximately 1.1 g/cm³
Vapor Pressure: Not measured; negligible at room temperature
Partition Coefficient: Log Pow - not determined
Flash Point: Not flammable under normal conditions
Auto-Ignition Temperature: Not established
Chemical Stability: Stable under recommended storage conditions
Hazardous Reactions: May react with oxidizing agents producing toxic gases
Conditions to Avoid: Excessive heat, moisture, light exposure, and strong acids or bases
Decomposition Products: Nitrogen oxides, hydrogen chloride, carbon monoxide, carbon dioxide may form at high temperatures
Polymerization: Not expected under normal handling and storage
Acute Toxicity: LD50 (oral, rat): reports vary from 56-290 mg/kg
Skin Corrosion/Irritation: Rated as irritant based on animal studies and structure-activity relationship
Serious Eye Damage/Irritation: Possible risk of eye damage or irritation
Respiratory Sensitization: May cause respiratory tract irritation if inhaled
Germ Cell Mutagenicity: Not listed as mutagenic; insufficient data
Carcinogenicity: Not identified as carcinogen by IARC, NTP or OSHA
Reproductive Toxicity: Not classified; insufficient human/animal data
Target Organ Effects: May affect central nervous system, cardiovascular, and respiratory systems
Ecotoxicity: Data unavailable for aquatic or terrestrial toxicity, but general practice avoids release into environment
Persistence and Degradability: Not rapidly degradable; chemical structure suggests slow breakdown in environment
Bioaccumulative Potential: No significant bioaccumulation expected based on physicochemical properties
Mobility in Soil: Expected to have some mobility in water due to high solubility
Other Adverse Effects: Do not allow material to contaminate surface water or sewers; avoid unnecessary environmental exposure
Disposal Methods: Dispose of in accordance with local, regional and national regulations; do not pour into drains or natural bodies of water
Contaminated Packaging: Triple rinse containers and dispose of in chemical waste collection; do not reuse packaging
Special Precautions: Incineration in approved facility recommended; consult local hazardous waste authorities for detailed procedures; keep records of disposal
UN Number: Not classified as dangerous for transport
Proper Shipping Name: Pargyline Hydrochloride, not regulated
Hazard Class: Not regulated
Packing Group: Not assigned
Environmental Hazards: Not a marine pollutant
Special Precautions for Transport: Protect containers from damage and leakage during transit; keep upright and secure in vehicles; ship in compliance with all applicable regulations
Regulatory Status: Not regulated as hazardous under OSHA Hazard Communication Standard or international equivalents
SARA Title III (Sections 302, 304, 311/312, 313): Not listed
TSCA: Listed
EINECS/ELINCS: Notified
WHMIS Classification: Not controlled under WHMIS
Other Regulations: Ensure compliance with all local, state, and national regulations regarding health, safety, and environmental protection
