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Product Name: P-Phenylenediamine Hydrochloride
Chemical Formula: C6H8N2·HCl
Synonyms: 1,4-Phenylenediamine monohydrochloride, p-Aminoaniline hydrochloride
CAS Number: 636-21-5
Recommended Uses: Hair dye intermediates, chemical synthesis, laboratory reagents
Supplier Information: Manufacturer/distributor address and emergency phone contact often appear on standard labels; these should always be referred to for immediate supply chain data
GHS Classification: Acute toxicity (oral, dermal, inhalation), Skin sensitizer, Eye irritant, Aquatic acute hazard
Signal Word: Danger
Hazard Statements: Toxic if swallowed, toxic in contact with skin, toxic if inhaled, causes skin irritation, may cause allergic skin reaction, causes serious eye irritation, very toxic to aquatic life
Pictograms: Skull and crossbones, exclamation mark, environment
Precautionary Statements: Avoid breathing dust, use protective gloves, keep away from food and drink, do not release into the environment
Chemical Name: P-Phenylenediamine Hydrochloride
Purity: Typically >98%
Impurities: Trace aniline derivatives
Molecular Weight: 144.60 g/mol
EINECS: 211-248-2
Other Components: No additional substances present meeting OSHA, ACGIH, NIOSH, or WHMIS hazardous substance criteria at reportable concentrations
Inhalation: Remove to fresh air, seek medical attention if symptoms like coughing, shortness of breath, or respiratory distress appear
Skin Contact: Remove contaminated clothing, wash skin with plenty of water and soap, get medical help if irritation develops or persists
Eye Contact: Rinse immediately with clean water for at least 15 minutes, lift upper and lower eyelids occasionally, contact an ophthalmologist
Ingestion: Do not induce vomiting; rinse mouth thoroughly with water, seek prompt medical support—provide the product label or SDS to responders
Suitable Extinguishing Media: Use water spray, foam, dry chemical, or carbon dioxide for small fires
Specific Hazards: Emits toxic fumes of nitrogen oxides and hydrochloric acid on decomposition or combustion
Protective Equipment for Firefighters: Self-contained breathing apparatus and full protective clothing
Special Procedures: Contain runoff from fire-fighting; prevent entry into drains or watercourses, ventilate area post-incident
Personal Precautions: Wear suitable chemical-resistant gloves, splash-proof goggles, an NIOSH-approved respirator in case of dust
Environmental Precautions: Prevent release to soil, waterways, and drains; inform authorities if contamination occurs
Cleanup Methods: Collect spillage by carefully sweeping or scooping into a suitable container, minimize dust generation, clean area with water and detergent, ventilate spaces involved
Handling: Use mechanical ventilation, keep containers tightly closed, avoid creating dust, minimize direct handling, avoid breathing dust or vapors, wash hands and exposed skin thoroughly after handling
Storage: Store in a cool, dry, well-ventilated place, away from sunlight, incompatible materials like oxidizers and strong acids, secure against unauthorized access
Occupational Exposure Limits: OSHA PEL (not established); recommended exposure: minimize as much as possible, check local listing
Engineering Controls: Local exhaust ventilation, closed systems or fume hood
Personal Protective Equipment (PPE): Disposable gloves (nitrile or neoprene), chemical-resistant lab coat, eye protection (goggles), NIOSH-approved respirator for powder handling or spill cleanups
Hygiene Measures: Change clothes if contaminated, avoid eating or drinking in the work area, clean hands before breaks and after exposure
Appearance: Off-white to light purple crystalline powder
Odor: Slight, amine-like
pH (1% solution): 3-5
Melting Point: 138-144°C
Boiling Point: Decomposes before boiling
Solubility: Soluble in water, slightly soluble in alcohol
Vapor Pressure: Negligible at 20°C
Density: Approx. 1.2 g/cm³
Partition Coefficient (n-octanol/water): No data available
Flash Point: Not applicable
Autoignition Temperature: Not established
Explosive Properties: Dust may form explosive mixture with air under certain conditions, but no documented explosions
Chemical Stability: Stable under recommended storage and handling conditions
Hazardous Reactions: Reacts with strong oxidizing agents, acids can speed up decomposition, may form toxic gases in contact with incompatible chemicals
Decomposition Products: Nitrogen oxides (NOx), hydrochloric acid fumes
Conditions to Avoid: Excess heat, open flame, incompatible material exposure
Polymerization: Not known to occur
Acute Toxicity: LD50 (oral, rat) ~80 mg/kg; LD50 (dermal, rabbit) ~300 mg/kg
Inhalation: Highly toxic by inhalation, causes respiratory irritation, coughing, potential for pulmonary edema
Skin Contact: Sensitizer, may provoke allergic reactions, redness, chemical burns
Eye Contact: Severe irritation, risk of permanent eye damage
Chronic Effects: Repeated or long-term exposure has been linked to skin sensitization, potential kidney and liver impairment
Mutagenicity/Carcinogenicity: No evidence in humans, not classified as carcinogen by IARC/NTP, mutagenic effects reported in in vitro systems
Reproductive Effects: Not adequately studied, avoidance during pregnancy advised
Ecotoxicity: Very toxic to aquatic organisms, LC50 (fish, 96hr): ~0.1 mg/L
Persistence and Degradability: Not readily biodegradable, can persist in the environment
Bioaccumulation Potential: Potential for bioaccumulation in aquatic environments, though data is limited
Mobility in Soil: Moderate mobility expected, may contaminate groundwater
Other Adverse Effects: Toxic byproducts possible if improperly disposed or burned
Disposal Methods: Handle waste as hazardous chemical; incinerate in a chemical incinerator equipped with afterburner and scrubber, or send through licensed hazardous waste disposal service
Container Disposal: Empty containers must be triple-rinsed, punctured or crushed before disposal per local regulation
Precautions: Avoid contact with drains and natural water systems during any disposal process, do not recycle contaminated waste
UN Number: 1673
UN Shipping Name: P-Phenylenediamine, hydrochloride
Class: 6.1 (Toxic substances)
Packing Group: II
Labels Required: Toxic (skull and crossbones), Environmentally hazardous
Transport Regulations: Subject to ADR, IMDG, IATA regulations for hazardous materials, keep in original packaging and clearly labeled during transportation
US TSCA: Listed
EU REACH: Subject to registration and restrictions
OSHA: Considered hazardous chemical
SARA Title III: Not listed as a reportable quantity, but follow local emergency planning guidelines
California Proposition 65: Not listed
WHMIS (Canada): Classified as D1A (immediate and serious toxic effects), D2B (toxic material causing other effects)
Other Regulations: Local, national, and international authorities require specific labeling, transport, and disposal measures due to toxicity and environmental impact; regular audit of workplace controls is recommended
