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Material Safety Data Sheet: P-Hydroxybenzaldehyde

Identification

Product Name: P-Hydroxybenzaldehyde
Synonyms: 4-Hydroxybenzaldehyde, p-Formylphenol
Chemical Formula: C7H6O2
Molecular Weight: 122.12 g/mol
CAS Number: 123-08-0
Recommended Uses: Flavoring agent, intermediate in organic synthesis, laboratory reagent
Supplier Identification: Company name and address as per purchasing documents
Emergency Contact: Local Poison Control Center or company emergency hotline
Restrictions on Use: For research and industrial use only, not intended for food or drug applications

Hazard Identification

GHS Classification: Eye irritation (Category 2A), Skin irritation (Category 2), Acute toxicity (oral, Category 4)
Signal Word: Warning
Hazard Statements: Causes skin and serious eye irritation, Harmful if swallowed
Pictograms: Exclamation Mark
Precautionary Statements: Avoid breathing dust, wash hands thoroughly after handling, wear protective gloves and eye protection, do not eat, drink, or smoke while using this product
Potential Health Effects: Inhalation can cause respiratory tract irritation, ingestion can lead to gastrointestinal discomfort, skin contact may trigger allergic reactions in sensitive individuals

Composition / Information on Ingredients

Chemical Name: P-Hydroxybenzaldehyde
Concentration: ≥99% by weight
Impurities: Trace levels of p-hydroxybenzoic acid or p-fluoro derivatives possible from manufacturing
Other Ingredients: No significant non-active ingredients present

First Aid Measures

Eye Contact: Rinse cautiously with water for several minutes, remove contact lenses if present and easy to do, continue rinsing, seek medical attention if irritation persists
Skin Contact: Wash affected area with soap and water, remove contaminated clothing and shoes, seek medical help if irritation or rash develops
Inhalation: Move exposed person to fresh air, keep at rest, seek medical attention if symptoms develop
Ingestion: Rinse mouth with water, do not induce vomiting, consult a medical professional immediately
Notes for Doctor: Treat symptomatically based on clinical judgement

Fire-Fighting Measures

Suitable Extinguishing Media: Water spray, alcohol-resistant foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Do not use high pressure water stream due to risk of spreading burning powder
Specific Hazards: Emits irritating and toxic fumes under fire conditions (carbon oxides), dust can form explosive mixtures with air
Protective Equipment & Precautions: Firefighters should wear self-contained breathing apparatus and full protective gear
Other Information: Prevent fire-fighting runoff from contaminating drains or natural waterways

Accidental Release Measures

Personal Precautions: Evacuate personnel, ensure adequate ventilation, avoid generation of dust, wear suitable protective equipment including gloves and goggles
Environmental Precautions: Prevent product from entering drains, soil, or waterways
Cleanup Methods: Scoop spilled material into a suitable container for disposal, avoid raising dust, ventilate area, wash spill site with soap and water after cleanup
Reference to Other Sections: Consult disposal considerations and exposure controls for further information

Handling and Storage

Safe Handling Practices: Use only with adequate ventilation, minimize dust generation, avoid skin and eye contact, wash hands thoroughly after handling, do not eat, drink, or smoke in work area
Storage Conditions: Store in a tightly closed container, keep in a cool, dry, well-ventilated area away from incompatible materials like strong oxidizers, acids, and bases
Incompatible Materials: Strong oxidizing agents, strong bases, strong acids
Special Storage Requirements: Protect from moisture and light, avoid extreme temperatures

Exposure Controls and Personal Protection

Exposure Limits: No established OSHA, NIOSH, or ACGIH exposure limits; minimize exposure as a precaution
Engineering Controls: Local exhaust ventilation, enclosed processes as feasible
Personal Protective Equipment: Chemical-resistant gloves (nitrile or butyl), safety goggles, lab coat or protective clothing
Respiratory Protection: Approved respirator recommended for airborne concentrations above safe limits
Hygiene Measures: Remove and wash contaminated clothing, avoid contact with skin, eyes, and clothing, wash hands before breaks and after work

Physical and Chemical Properties

Appearance: Pale yellow to light beige crystalline solid or powder
Odor: Faintly almond or aromatic
Odor Threshold: Not determined
pH: Not applicable for solid form
Melting Point: 114-116°C
Boiling Point: 275°C
Flash Point: 156°C (closed cup)
Evaporation Rate: Not determined
Flammability: Dust may be combustible
Upper/Lower Flammability Limits: No data available
Vapor Pressure: Negligible at 20°C
Vapor Density: Not determined
Relative Density: 1.25 g/cm³
Solubility: Slightly soluble in water, more soluble in ethanol, diethyl ether
Partition Coefficient (n-octanol/water): Log Kow 1.09
Auto-ignition Temperature: Not available
Decomposition Temperature: Decomposes above melting point
Viscosity: Not applicable

Stability and Reactivity

Chemical Stability: Stable under normal temperatures and pressures
Reactivity: Not highly reactive under normal conditions
Hazardous Reactions: No polymerization expected
Conditions to Avoid: Excess heat, direct sunlight, moisture, dust accumulation
Incompatible Materials: Strong oxidizers, strong acids or bases may cause hazardous reactions
Hazardous Decomposition Products: May generate carbon monoxide, carbon dioxide, other toxic vapors when burned or decomposed thermally

Toxicological Information

Routes of Entry: Inhalation, ingestion, skin and eye contact
Acute Toxicity: Oral LD50 (rat): approx. 1800 mg/kg
Chronic Toxicity: Prolonged exposure may cause dermatitis or sensitization in susceptible individuals
Skin Corrosion/Irritation: May cause redness, irritation
Serious Eye Damage/Irritation: Causes moderate to severe irritation
Respiratory Sensitization: Not classified
Germ Cell Mutagenicity: Data not sufficient
Carcinogenicity: Not listed by NTP, IARC, or OSHA as a carcinogen
Reproductive Toxicity: No data indicating reproductive harm
Specific Target Organ Toxicity: No known specific hazards beyond general irritation
Other Effects: Dust may aggravate existing lung conditions in sensitive users

Ecological Information

Aquatic Toxicity: Not acutely toxic, but may cause temporary adverse effects in aquatic environments, specific LC50/EC50 values not established
Persistence and Degradability: Expected to biodegrade slowly, stable under ambient conditions
Bioaccumulative Potential: Low due to modest log Kow value
Mobility in Soil: Low mobility, some adsorption on organic matter anticipated
Other Adverse Effects: Avoid release to environment as a routine caution; chemical may disrupt microorganism activity in high concentrations

Disposal Considerations

Product Recovery: Whenever practical, recover and recycle material for reuse
Waste Disposal Methods: Dispose of contents in accordance with local, regional, national, and international regulations as hazardous chemical waste
Packaging Disposal: Triple rinse containers, puncture or crush, then dispose of as regulated chemical packaging
Special Precautions: Do not allow chemical to enter drains, sewers, or natural waterways
Recommended Handling for Waste: Incinerate in a chemical incinerator with afterburner and scrubber where permitted by law

Transport Information

UN Number: Not regulated under UN transport classification for most modes
Proper Shipping Name: Not regulated — refer to local and carrier-specific guidance
Transport Hazard Class: No assigned hazard class
Packing Group: No assigned packing group
Marine Pollutant: Not designated as a marine pollutant
Special Precautions for Transport: Protect from physical damage and moisture, secure containers during transport, prevent spills

Regulatory Information

USA TSCA: Listed on Toxic Substances Control Act inventory
EU REACH: Notified or registered as required
Other International Regulations: Product meets Canadian DSL/NDSL requirements, complies with Japanese ENCS listings, checked on Australian AICS and Chinese IECSC inventories
Right-to-Know Information: Not listed under California Proposition 65, SARA Title III, or similar lists
Labeling Requirements: Use GHS symbols and safety phrases covered above
Worker Protection Standards: Follow laboratory chemical hygiene plans and workplace-specific requirements