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Product Name: Oxfendazole
Chemical Name: Methyl 5-(phenylsulfinyl)-2-benzimidazolecarbamate
Synonyms: Synanthic, Bentacare, Oxim
CAS Number: 53716-50-0
Intended Use: Veterinary anthelmintic (dewormer for livestock)
Manufacturer: [Manufacturer’s name]
Emergency Contact: [Emergency phone number]
Hazard Classification: Harmful if swallowed; may cause eye and skin irritation; may damage fertility or the unborn child; toxic to aquatic life with long-lasting effects
Signal Word: Warning
Hazard Statements: Causes serious eye irritation; may cause respiratory irritation; harmful to aquatic life
Pictograms: Exclamation mark, health hazard, environment
Routes of Exposure: Inhalation, ingestion, skin and eye contact
Precautionary Statements: Avoid breathing dust; wear protective gloves and clothing; wash hands thoroughly after handling; avoid release to the environment
Chemical Identity: Oxfendazole
CAS Number: 53716-50-0
Concentration: >98% (technical grade)
Impurities: Benzimidazole derivatives (trace); solvents (depending on formulation)
General Information: Move exposed individual away from hazardous area; provide fresh air; keep at rest
If Inhaled: Move person to fresh air; seek medical attention if symptoms occur
If on Skin: Remove contaminated clothing; wash skin with plenty of water; consult a physician if irritation develops
If in Eyes: Rinse cautiously with water for several minutes; remove contact lenses if present; seek medical attention if irritation persists
If Swallowed: Rinse mouth; do not induce vomiting; seek medical advice immediately; show this sheet to the doctor
Advice for Medical Professionals: Symptomatic treatment; monitor respiratory and cardiovascular functions; treat as per symptoms
Suitable Extinguishing Media: Water spray, foam, dry chemical powder, carbon dioxide
Unsuitable Extinguishing Media: Full water jet
Special Hazards Arising: May release toxic fumes of nitrogen oxides, sulfur oxides, carbon oxides under fire conditions
Protective Equipment: Self-contained breathing apparatus; full protective clothing
Additional Advice: Control run-off water; keep containers cool with water spray; avoid inhaling combustion products
Personal Precautions: Wear personal protective equipment; avoid dust formation; ensure adequate ventilation
Environmental Precautions: Prevent product from entering drains or watercourses; avoid further leakage or spillage
Spill Containment: Sweep up and collect spilled substance into suitable containers for disposal; clean area thoroughly with detergent and water; dispose of according to local regulations
Reference to Other Sections: See Sections 8 and 13 for personal protection and disposal
Handling: Avoid contact with skin, eyes, and clothing; avoid creating dust; wear appropriate personal protective gear; do not eat, drink, or smoke when using this product; wash hands after use
Storage: Store in tightly closed original containers; keep in a cool, dry, well-ventilated area; protect from sunlight and moisture; keep away from food, feed, and water sources
Incompatible Materials: Strong acids, strong bases, strong oxidizing agents
Specific End Uses: For professional use in animal health care
Exposure Limits: No specific occupational exposure limit established for Oxfendazole; minimize exposure as far as possible
Engineering Controls: Use adequate ventilation, fume hoods, or local exhaust to keep airborne concentrations below exposure limits
Personal Protective Equipment (PPE):
Appearance: White to off-white crystalline powder
Odor: Odorless
Molecular Formula: C15H13N3O3S
Molecular Weight: 315.35 g/mol
Melting Point: 205–210°C
Boiling Point: Not applicable/decomposes before boiling
Solubility: Slightly soluble in water; soluble in ethanol, acetone, chloroform
Vapor Pressure: Negligible
Density: Approximately 1.45 g/cm3
pH: Not determined (insoluble in water)
Partition Coefficient (n-octanol/water): 2.5–3.0 (estimated)
Other Data: Stable under recommended storage conditions
Chemical Stability: Product remains stable under normal conditions of use and storage
Reactivity: Does not react with common materials under normal conditions
Hazardous Reactions: Exposure to strong oxidizers, acids, or bases can lead to degradation and hazardous decomposition
Conditions to Avoid: Excess heat, sources of ignition, direct sunlight, incompatible chemicals
Hazardous Decomposition Products: Nitrogen oxides, sulfur oxides, carbon oxides
Acute Toxicity: Oral LD50 (rat): 2,300 mg/kg; inhalation and dermal toxicity data not fully established
Chronic Toxicity: Prolonged exposure may affect liver and blood parameters
Skin Contact: May cause mild irritation
Eye Contact: Causes irritation, redness, watering
Inhalation: May cause respiratory tract irritation; dust exposure should be minimized
Sensitization: Not a known skin sensitizer in animal studies
Reproductive/Developmental Effects: Evidence suggests potential risk to unborn child at high exposure levels in lab animals
Carcinogenicity: Not listed as a carcinogen by NTP, IARC, or OSHA
Other Effects: Possible effects on the blood and liver after large doses or prolonged exposure based on animal data
Environmental Fate: Not highly soluble in water; may persist in soil as a result
Aquatic Toxicity: Toxic to aquatic organisms; LC50 (fish): 0.82 mg/L (96h, rainbow trout); chronic exposure affects aquatic invertebrates
Persistence and Degradability: Low biodegradability in soil and water; can accumulate in environments with continual use
Bioaccumulation: Moderate potential due to partition coefficient
Mobility in Soil: Tend to bind with soil particles, limiting groundwater contamination risk
Other Adverse Effects: Avoid release to the environment due to chronic risk to aquatic and non-target organisms
Waste Treatment Methods: Collect product and contaminated material in appropriate containers; do not reuse empty containers
Disposal of Product: Dispose of in accordance with local, regional, national, and international regulations; incineration in approved facility recommended
Disposal of Packaging: Triple-rinse before disposal; do not allow material to enter sewers, surface water, or groundwater
Other Disposal Considerations: Consult local environmental authorities for guidelines specific to your location
UN Number: UN 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Oxfendazole)
Transport Hazard Class(es): 9 (Miscellaneous dangerous substances and articles)
Packing Group: III
Environmental Hazards: Marine pollutant
Special Precautions: Avoid direct contact and use original container; transport according to applicable laws and regulations; emergency response guide available
TSCA Status: Listed
ECHA REACH Status: Registered substance or exempt for veterinary use
OSHA: Not classified as hazardous chemical under OSHA GHS regulations
US EPA: Registered active ingredient for veterinary use; not approved for human consumption
Other Regulations: Subject to local and national regulations regarding storage, use, and disposal
Labeling Requirements: Ensure containers display hazard symbols, precautionary statements, and product identification information
Workplace Hazard Communication: Safety training for handlers; clear access to Safety Data Sheets for all employees
