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Product Name: Octylphenol
Chemical Name: 4-(1,1,3,3-Tetramethylbutyl)phenol
Common Synonyms: p-Octylphenol, para-Octylphenol
CAS Number: 140-66-9
Recommended Use: Used in chemical manufacturing, surfactants, resins, and as intermediates in industrial processes
Supplier Details: Supplied by various chemical manufacturers; refer to container label for specific supplier information
Emergency Contact: Refer to manufacturer instructions and local poison control hotline for incidents or emergencies
Contact Phone Number: See safety label or SDS supplied by manufacturer
Physical Hazards: May cause irritating fumes if involved in fire or exposed to high temperatures; burns skin and eyes on direct contact
Health Hazards: Causes severe eye damage and skin irritation, suspected to disrupt endocrine system, harmful if swallowed, affects aquatic organisms with long-lasting effects
Environmental Hazards: Highly toxic to aquatic life and persists in natural ecosystems, accumulates in wildlife and plants, potential threat to fish, amphibians, birds
Hazard Symbols: Corrosion, Environment
GHS Classification: Acute toxicity (Oral, Category 4), Skin irritation (Category 2), Eye damage (Category 1), Hazardous to the aquatic environment (Category 1)
Signal Word: Danger
Precautionary Statements: Avoid breathing dust, avoid environmental release, wear protective equipment, wash exposed areas thoroughly after use
Substance Name: Octylphenol
Chemical Formula: C14H22O
CAS Number: 140-66-9
Concentration: 98-100% by weight
Impurities: Trace amounts of isomers or related phenol derivatives may be present depending on batch
Eye Contact: Immediately flush eyes with plenty of water for at least 15 minutes, lifting eyelids occasionally, remove contact lenses, seek urgent medical attention for persistent irritation
Skin Contact: Remove contaminated clothing, rinse affected area with lots of water and soap, if redness or burning persists get medical help
Inhalation: Move person to fresh air, support breathing if needed, provide oxygen if breathing is difficult, seek medical care for severe symptoms
Ingestion: Rinse mouth with water if safe to do so, do not induce vomiting unless told to by medical personnel, get medical help quickly
Key Symptoms: Irritation, burns, headache, nausea, coughing, abdominal pain
Medical Attention: Give MSDS to healthcare provider, monitor for delayed symptoms
Suitable Extinguishing Media: Use foam, dry chemical, or carbon dioxide for small fires; use water spray to cool containers though direct stream may spread material
Hazards from Combustion: Produces carbon oxides, phenolic fumes, and possible toxic vapors above normal smoke
Protective Equipment for Firefighters: Wear full protective gear: self-contained breathing apparatus, gloves, and fire-resistant clothing, avoid inhalation of vapors
Special Firefighting Procedures: Dike runoff to prevent entry to water or sewer, remove containers from fire area if safe to do so
Explosion Risk: May form explosive mixtures with air, especially in poorly ventilated spaces
Personal Precautions: Evacuate area, ensure adequate ventilation, stay upwind, wear chemical splash goggles, gloves, protective clothing, and respiratory protection as needed
Environmental Precautions: Prevent entry into drains, soil, and waterways, contain spill to smallest area, alert local environmental authorities if release is large or affects water
Clean-up Methods: Absorb spilled material with inert absorbent (sand, earth, vermiculite), use non-sparking tools, scoop up and place in appropriate container for disposal, wash area with detergent and water
Disposal: Collected waste must be packaged for hazardous waste disposal following local regulations, do not flush to sewer
Handling: Minimize direct contact, keep away from food or drink, avoid breathing dust or vapor, wear protective equipment and use with local exhaust and good ventilation
Safe Storage Conditions: Store in tightly closed original container, in cool, dry, well-ventilated area, keep away from incompatible substances (oxidizers, acids), avoid sunlight, keep away from children and unauthorized persons
Bulk Storage Guidance: Use corrosion-resistant materials for storage tanks and lines, prevent spills and secondary containment leaks, clearly label storage vessels
Occupational Exposure Limits: No established OSHA PEL or ACGIH TLV; use control banding and good practice to minimize exposure
Engineering Controls: Provide local exhaust ventilation and closed systems where possible, use fume hoods for laboratory work
Respiratory Protection: Use NIOSH-approved cartridge respirator if potential for exposure exists, especially at high concentrations
Skin Protection: Wear impervious gloves (nitrile, neoprene), long-sleeved clothing, apron
Eye Protection: Use tightly sealed goggles and face shield in splash-risk situations
Hygiene Measures: Wash thoroughly after handling, remove contaminated clothes, do not eat, drink, or smoke near substance
Appearance: Colorless to pale yellow, oily liquid
Odor: Characteristic, phenolic smell
Melting Point: Approximately -1°C
Boiling Point: Around 286°C
Flash Point: 137°C (closed cup)
Vapor Pressure: 0.0027 mmHg at 25°C
Density: 0.947 g/cm³ at 20°C
Solubility: Poorly soluble in water (7 mg/L at 20°C), soluble in alcohols and organic solvents
pH: Not measurable as neutral liquid, slightly acidic traits
Partition Coefficient (log Kow): 5.3 (predicted high potential for bioaccumulation)
Viscosity: Oily; increases in cold
Autoignition Temperature: 365°C
Chemical Stability: Stable under normal temperatures and pressures, degrades slowly in sunlight, may react with oxidizing agents
Incompatible Materials: Strong acids, strong oxidizers, peroxides
Hazardous Decomposition: Carbon monoxide, carbon dioxide, phenolic fumes if burned or decomposed
Polymerization: Will not occur under normal handling
Conditions to Avoid: Heat, flames, ignition sources, incompatible materials
Routes of Exposure: Inhalation, skin, eyes, gut
Acute Toxicity: Oral LD50 in rats: 1,800 mg/kg; skin LD50 in rabbits: >2,000 mg/kg
Irritation: Strong irritation and burns possible for eyes and mucous membranes; causes severe skin inflammation
Sensitization: Not classified as a skin sensitizer, but repeated contact may increase susceptibility
Chronic Effects: Endocrine disruptor in laboratory animals, liver and kidney changes on high dose, possible reproductive toxicity
Carcinogenicity: Not identified as carcinogen by NTP, IARC, OSHA
Mutagenicity: Not known to cause heritable genetic mutations at expected exposure
Other Effects: Headaches, nausea, temporary breathing difficulty, effects on aquatic life chronic exposure
Ecotoxicity: Highly toxic to aquatic species, especially fish and invertebrates, LC50 (fish, 96 hr): about 0.027 mg/L; long-term effects are significant in rivers
Mobility in Soil: Low mobility, binds strongly to organic soil, potential for groundwater contamination if mismanaged
Persistence and Degradability: Breaks down slowly in environment, persists in water and sediments, resists biological breakdown
Bioaccumulation Potential: Bioaccumulative, especially in aquatic organisms and up the food chain
Other Adverse Effects: Disrupts hormone systems in aquatic wildlife, affects eggs and larvae development
Waste Handling: Dispose as hazardous chemical waste, keep in labeled, sealed containers until collection, separate from non-hazardous waste
Disposal Methods: Incinerate in approved industrial facility, do not release to environment, follow regional and local environmental authority regulations
Packaging Disposal: Containers must be completely empty, triple-rinsed, and punctured before disposal; should only be recycled or disposed of as hazardous waste
Special Precautions: Avoid spillage during transfer and keep spill management materials nearby, never dispose of in regular trash or sewers
UN Number: 3077
UN Proper Shipping Name: Environmentally hazardous substance, solid, n.o.s. (Octylphenol)
Transport Hazard Class: 9 (Miscellaneous dangerous goods)
Packing Group: III
Marine Pollutant: Yes
Label: Miscellaneous dangerous goods, Marine Pollutant
Special Transport Precautions: Use sealed containers, avoid transport with incompatible materials, protect from transport accidents, comply with all regulatory requirements
OSHA: Not specifically listed, general hazardous substance rules apply
TSCA (US): Listed and subject to reporting and restrictions
REACH (EU): Registered substance, subject to authorization and restriction procedures
California Proposition 65: Not listed as carcinogen or reproductive toxin
WHMIS (Canada): Classified as toxic (E), and as an irritant
Other Regional Regulations: Many countries restrict aquatic releases and require authorizations for use in manufacturing
Worker Safety: Proper training and documentation required for those in contact with material, follow workplace safety signage and notifications
