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Product Name: Octadecanoyl Chloride
Synonyms: Stearoyl Chloride, n-Octadecanoyl Chloride
CAS Number: 112-76-5
Recommended Use: Industrial and laboratory chemical synthesis, common in pharmaceutical and chemical manufacturing
Company/Contact: Refer to local chemical distributor or supplier for emergency telephone number and address
Emergency Contacts: Local/national poison control center, fire department, or occupational safety authority
GHS Classification: Skin Corrosion/Irritation Category 1B, Serious Eye Damage Category 1, Acute Toxicity Oral Category 4
Signal Word: Danger
Hazard Statements: Causes severe skin burns and eye damage. Harmful if swallowed. May cause respiratory irritation if inhaled.
Pictograms: Corrosive, Exclamation mark
Precautionary Statements: Avoid breathing dust, fume, gas, mist, vapors, or spray. Wash hands and exposed skin thoroughly after handling. Wear protective gloves, clothing, and eye/face protection.
Potential Health Effects: Strongly corrosive to tissues; may damage skin, eyes, and mucous membranes on contact; possible respiratory tract irritation.
Chemical Name: Octadecanoyl Chloride
CAS No.: 112-76-5
Concentration: 98–100%
Other Ingredients: None significant
Impurities: Trace organochlorine compounds; detailed impurity content available from the supplier’s batch-specific COA.
Eye Contact: Immediately flush eyes with copious amounts of water for at least 15 minutes; remove contact lenses if present and easy to do; continue rinsing and seek medical attention.
Skin Contact: Remove contaminated clothing. Rinse affected area with water for at least 15 minutes. Do not use neutralizing agents unless instructed by medical personnel. Call for medical help.
Inhalation: Move person to fresh air. Seek immediate medical attention. Apply artificial respiration if breathing stops. Oxygen may be required by trained personnel.
Ingestion: Rinse mouth thoroughly. Do not induce vomiting. Never give anything by mouth to an unconscious person. Get medical attention immediately.
Suitable Extinguishing Media: Use dry chemical, carbon dioxide, or alcohol-resistant foam. Water spray may cause violent reaction with product.
Hazardous Combustion Products: Hydrogen chloride gas, carbon monoxide, carbon dioxide, chlorine compounds.
Special Protective Equipment: Firefighters should use self-contained breathing apparatus and protective clothing to prevent contact with skin and eyes. Move containers from fire area if safe.
Specific Fire Hazards: May decompose or react violently with water; corrosive vapors can form; heat can increase pressure in closed containers which may rupture.
Personal Precautions: Evacuate area, keep upwind, ventilate enclosed spaces, avoid inhalation and skin/eye contact. Use proper PPE: gloves, goggles, impermeable clothing, and respiratory protection.
Environmental Precautions: Prevent spills from entering drains, surface waters, and soil. Notify authorities if product contaminates the environment.
Clean-Up Methods: Contain leak with dry inert material (sand, earth). Do not use water for containment or cleanup. Carefully collect into appropriate chemical waste container. Wash area with a small quantity of water once material is contained, followed by neutralization with dilute alkaline solution under expert supervision.
Handling: Work in a chemical fume hood or well-ventilated area. Avoid breathing vapors, dust, or mist. Avoid contact with skin, eyes, clothing. Use only with proper PPE. Keep container tightly closed when not in use. Do not ingest.
Storage: Store in cool, dry, well-ventilated space, away from incompatible chemicals such as water, alcohols, strong bases, and oxidizers. Use corrosion-resistant containers. Protect from moisture and direct sunlight.
Special Considerations: Label containers clearly. Store below 30°C. Keep ready access to emergency equipment and wash stations.
Exposure Limits: No occupational exposure limits established for Octadecanoyl Chloride. Handle as highly corrosive substance; consult national guidelines.
Engineering Controls: Use only in chemical fume hood with adequate local exhaust ventilation.
Personal Protection: Wear chemical splash goggles, face shield, acid-resistant gloves, long sleeves, lab coat, and impervious apron. Use approved respirators (PPE) for vapors or dust, especially in non-ventilated situations.
Hygiene Measures: Wash hands and skin thoroughly after handling. Take off contaminated clothing and wash before reuse.
Appearance: White to light yellow waxy solid or powder
Odor: Pungent, acrid
Molecular Formula: C18H35ClO
Molecular Weight: 302.92 g/mol
Boiling Point: Decomposes above 375°C
Melting Point: 40–42°C
Solubility: Decomposes in water; soluble in most organic solvents (e.g., benzene, chloroform, ether)
Vapor Pressure: Negligible at room temperature
Density: 0.92–0.97 g/cm³ @ 20°C
pH: Not applicable (reacts in water)
Flash Point: Not established
Chemical Stability: Stable under recommended storage and handling conditions. Moisture sensitive.
Reactivity: Reacts violently with water and alcohols, forming stearic acid and hydrochloric acid.
Hazardous Reactions: Can generate heat and corrosive byproducts when exposed to moisture, bases, or oxidizers.
Decomposition Products: Carbon dioxide, carbon monoxide, hydrogen chloride, stearic acid.
Conditions to Avoid: Contact with water, damp air, strong alkalis, oxidizing agents.
Acute Toxicity: Harmful if swallowed. May cause burns to digestive tract. LD50 (oral, rat): approx. 1,800 mg/kg.
Skin Contact: Causes severe burns, can cause necrosis after prolonged exposure.
Eye Contact: Severe eye burns, possible permanent damage or blindness.
Inhalation: Causes respiratory tract irritation, risk of pulmonary edema with prolonged exposure.
Chronic Effects: No known long-term carcinogenic, mutagenic, or reproductive toxicity reported for Octadecanoyl Chloride.
Aquatic Toxicity: May be toxic to aquatic life due to acidity and corrosiveness. Direct contamination can change pH and harm organisms.
Persistence/Degradability: Hydrolyzes quickly in water to stearic acid and hydrochloric acid. Degradation products are less harmful.
Bioaccumulation: Not expected due to rapid hydrolysis.
Mobility in Soil: Product reacts with soil moisture, binding rapidly and breaking down.
Other Effects: Avoid release to the environment. Follow national and local regulations for reporting and cleanup.
Waste Treatment Methods: Dispose of waste in accordance with local and national regulations. Neutralize in controlled facility before disposal. Do not release to sewage systems.
Container Disposal: Rinse empty containers three times with suitable solvent; render container unusable and dispose in licensed facility.
Special Precautions: Clean up and handle waste using PPE and only by trained personnel.
UN Number: 3261
Proper Shipping Name: Corrosive solid, acid, organic, n.o.s. (Octadecanoyl Chloride)
Transport Hazard Class: 8 (Corrosive)
Packing Group: II
Marine Pollutant: Not listed, but spills into water pose environmental risks.
Special Precautions: Use corrosion-resistant packaging. Keep separate from incompatible chemicals.
Safety, Health, and Environmental Regulations: Octadecanoyl Chloride appears on several chemical inventories. Subject to local, national, and international rules for hazardous substances.
OSHA Status: Corrosive; handle following OSHA standards for corrosives.
TSCA: Listed.
EINECS: Registered, EINECS number 204-014-2.
WHMIS Classification: Class E, corrosive material.
SARA Title III: Not specifically listed, but hazardous by nature.
Chemical Restrictions: Not for use in consumer products; industrial and research use only.
Other Labeling: Adhere to EU CLP, GHS, and national hazard labeling.
