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Product Name: O-Phenylenediamine Hydrochloride
Chemical Formula: C6H8ClN2
CAS Number: 4151-50-2
Synonyms: 1,2-Benzenediamine hydrochloride, ortho-Phenylenediamine hydrochloride
Recommended Use: Laboratory chemical, reagent in analytical chemistry, dye manufacture
Supplier: Laboratory and industrial chemical distributors across global markets
Contact Information: Reach out to supplier or workplace safety officer for specifics
GHS Classification: Acute Toxicity (Oral) Category 3, Acute Toxicity (Dermal) Category 3, Skin Irritation Category 2, Eye Irritation Category 2, Sensitization – Skin Category 1
Signal Word: Danger
Hazard Statements: Toxic if swallowed, toxic in contact with skin, causes skin irritation, causes serious eye irritation, may cause an allergic skin reaction
Pictograms: Skull and crossbones, exclamation mark
Precautionary Statements: Do not breathe dust or fumes, wash hands thoroughly after handling, wear protective gloves and eye protection, use appropriate engineering controls
Chemical Name: O-Phenylenediamine Hydrochloride
Concentration: 98-100% by weight
Impurities: May contain small traces of other organic amines or related hydrochloride salts depending on purity grade
Molecular Weight: 144.6 g/mol
Inhalation: Move to fresh air, keep person at rest, seek immediate medical attention. Provide supplemental oxygen if breathing difficulty persists.
Eye Contact: Rinse eyes with running water for at least 15 minutes, lift eyelids to ensure thorough cleaning, call a physician.
Skin Contact: Immediately remove contaminated clothing, wash exposed skin thoroughly with soap and water for several minutes, get medical attention if irritation develops.
Ingestion: Do not induce vomiting, rinse mouth thoroughly with water, seek immediate medical help. If patient is conscious, offer small quantities of water.
Medical Attention: Physicians should monitor for respiratory distress, skin sensitivity, or allergic reaction.
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide, or water spray can be used on small fires.
Unsuitable Extinguishing Media: Direct water streams may spread spilled material or contaminate areas.
Fire/Explosion Hazards: Emits toxic fumes of nitrogen oxides, carbon monoxide, hydrogen chloride under fire conditions.
Protective Equipment: Firefighters should wear self-contained breathing apparatus and full protective gear.
Firefighting Precautions: Approach fire from upwind to avoid hazardous byproducts, use chemical-resistant gloves and boots.
Personal Precautions: Wear appropriate chemical-resistant gloves, safety goggles, and lab coat or chemical suit. Keep unprotected individuals away from spill area.
Environmental Precautions: Prevent entry into waterways, storm drains, or soil, contain spill with inert absorbent material.
Methods for Cleanup: Scoop or sweep up without generating dust, place in tightly sealed waste containers, ventilate area thoroughly.
Disposal of Contaminated Material: Dispose of contaminated cleanup tools as hazardous waste. Wash area with diluted bleach followed by water to remove residue.
Handling: Avoid contact with skin, eyes, and clothing during transfer or weighing, work in well-ventilated areas or chemical fume hoods. Observe industrial hygiene practices such as frequent hand washing after use.
Storage: Keep container tightly sealed in a dry, well-ventilated area away from incompatible substances like oxidizers. Store at room temperature or as directed by manufacturer. Place clearly labeled containers on shelves or cabinets designed for toxic chemicals. Protect from heat, moisture, direct sunlight, and source sparks.
Engineering Controls: Practice work in fume hoods or local exhaust systems when possible, ensure emergency eyewash and safety showers are nearby. Validate area ventilation on a regular schedule.
Personal Protective Equipment (PPE): Use chemical safety goggles, nitrile or neoprene gloves, protective lab coats or aprons, closed-toe shoes. Respiratory protection may be needed for dusty operations.
Occupational Exposure Limits: No official OSHA or ACGIH TLV values published for this compound, minimize exposure as much as possible.
Hygiene Measures: Wash hands and face thoroughly after handling, change and launder contaminated clothing before reuse.
Appearance: Pale yellow to buff colored crystalline powder
Odor: Faint, aromatic amine-like scent
Melting Point: 225-230°C (decomposes)
Boiling Point: Not applicable (decomposes before boiling)
Solubility: Freely soluble in water, limited solubility in ethanol
pH (1% solution): ~2 (acidic)
Density: 1.33 g/cm³
Vapor Pressure: Negligible at room temperature
Flammability: Not classified as flammable in solid form
Partition Coefficient: Not established
Chemical Stability: Stable under recommended storage conditions. Prolonged exposure to air and humidity may lead to slow degradation.
Reactivity: Reacts with strong oxidizers, acids, and nitrites, which may produce toxic gases.
Hazardous Decomposition Products: Nitrogen oxides, hydrogen chloride, carbon monoxide and carbon dioxide released during decomposition or fire.
Polymerization: No known hazardous polymerization.
Incompatible Materials: Avoid contact with copper, strong acids, or alkali metals.
Acute Toxicity: Oral LD50 (rat): 56 mg/kg. Dermal LD50 (rabbit): <300 mg/kg. Causes symptoms including headache, nausea, abdominal pain, and drowsiness; severe poisoning leads to convulsions, methemoglobinemia, or death.
Routes of Entry: Ingestion, inhalation, and skin absorption.
Chronic Effects: Prolonged exposure has resulted in allergic skin reactions, dermatitis, and possible sensitization in some individuals.
Carcinogenicity: Not listed as a carcinogen by IARC, NTP, or OSHA, but some aromatic amines have raised concern in occupational exposures.
Other Data: May cause hematologic changes and respiratory tract irritation on repeated exposure.
Ecotoxicity: Harmful to aquatic life, causes acute and chronic toxicity in fish and invertebrates at low concentrations.
Persistence and Degradability: Moderate persistence in soil and water; slowly degrades under aerobic conditions.
Bioaccumulative Potential: Not expected to bioaccumulate significantly due to water solubility.
Mobility in Soil: Mobile in water due to solubility, may leach into groundwater from contaminated sites.
Environmental Precautions: Do not allow large quantities to reach sewage systems, waterways, or soil.
Waste Disposal: Treat as hazardous chemical waste, collect and store in properly labeled approved containers for disposal at licensed chemical treatment facilities.
Contaminated Packaging: Empty containers retain hazardous residues and should be handled as hazardous waste; avoid reuse.
Regulatory Compliance: Follow local, regional, and national environmental regulations for hazardous chemical disposal. Incineration or chemical neutralization may be suitable disposal routes with appropriate permits.
UN Number: 2811
Proper Shipping Name: Toxic Solid, Organic, N.O.S. (O-Phenylenediamine Hydrochloride)
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: III
Environmental Hazards: Harmful to environment if released during transit.
Special Transport Precautions: Package containers tightly, mark clearly with appropriate hazard labels. Store away from food and animal feeds during transport.
OSHA: Hazardous chemical as defined by OSHA Hazard Communication Standard (29 CFR 1910.1200).
SARA Title III: Subject to reporting under SARA Title III, Section 313 (Toxic Chemical Release Inventory).
TSCA Inventory: Listed.
REACH Status: Pre-registered, subject to specific restrictions in the EU.
Canadian WHMIS: Classified as toxic material, subject to workplace disclosure and risk mitigation measures.
Labeling Requirements: Signal words, hazard pictograms, and detailed hazard statements must be displayed on all shipping and primary containers.
