© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: O,O,O',O'-Tetraethyl Dithiopyrophosphate
Synonyms: Tetraethyl dithiopyrophosphate, TEPP
CAS Number: 107-49-3
Recommended Use: Insecticide, chemical intermediate
Manufacturer: [Contact information required by local regulations]
Emergency Phone: [Local emergency contact]
Formula: C8H20O4P2S2
Supplier Information: [Supplier name, address, phone]
Classification: Acute Toxicity (Oral) - Category 1; Skin Irritation - Category 2; Eye Damage/Irritation - Category 2A
Label Elements: Danger, Skull and Crossbones, Exclamation Mark
Signal Word: Danger
Hazard Statements: Fatal if swallowed; causes skin irritation; causes serious eye irritation; suspected of causing genetic defects
Precautionary Statements: Do not breathe dust/fume/gas/mist/vapors/spray; wash hands thoroughly after handling; wear protective gloves/protective clothing/eye protection/face protection;
Main Health Hazards: Cholinesterase inhibitor, impacts nervous system, rapid onset of symptoms possible
Routes of Exposure: Inhalation, ingestion, skin contact, eye contact
Environmental Hazards: Considered hazardous to aquatic life, bioaccumulation possible
Chemical Name: O,O,O',O'-Tetraethyl Dithiopyrophosphate
CAS No.: 107-49-3
Concentration: 99% minimum
Impurities: Traces of diethyl phosphorodithioate, diethyl phosphate
Molecular Weight: 322.32 g/mol
Inhalation: Move victim to fresh air immediately, keep warm and at rest; seek medical attention without delay; support breathing if necessary
Ingestion: Rinse mouth with water, do not induce vomiting, contact poison control and get immediate medical help; if unconscious do not give anything by mouth
Skin Contact: Remove contaminated clothing, wash skin with soap and plenty of water for 15 minutes minimum; seek medical attention for symptoms; wash clothing before reuse
Eye Contact: Rinse with gentle stream of water for at least 15 minutes, lifting upper and lower eyelids occasionally; obtain medical attention as soon as possible
Most Important Symptoms and Effects: Muscle twitching, pinpoint pupils, headache, nausea, breathing difficulty, possible convulsions
Information to Physician: Treat with atropine sulfate and pralidoxime chloride as antidotes for organophosphate poisoning
Suitable Extinguishing Media: Dry chemical, foam, carbon dioxide; water spray for cooling containers
Unsuitable Extinguishing Media: Full water jet may spread material
Specific Hazards: Toxic or irritating gases may form on combustion: phosphorus oxides, sulfur oxides, ethylene
Special Protective Equipment for Firefighters: Full protective gear and self-contained breathing apparatus
Explosion Data: Not sensitive to impact; avoid sources of ignition; vapors may form explosive mixtures with air in confined spaces
Firefighting Instructions: Approach from upwind, avoid breathing fumes; use water spray to cool containers exposed to fire
Personal Precautions: Evacuate area, ensure adequate ventilation, wear chemical-resistant gloves, boots, eye protection, and respirator
Environmental Precautions: Prevent liquid from entering drains, water bodies or soil; contain spill with earth or inert material
Cleanup Methods: Absorb with sand or suitable absorbent; collect in tightly sealed containers for disposal; clean contaminated surface with detergent and water
Decontamination: Use dilute sodium hydroxide and wash surface thoroughly
Disposal: Dispose of in accordance with local and national regulations; incineration preferred for residues
Handling: Work in chemical fume hood or well-ventilated area; avoid inhalation, ingestion, skin and eye contact; use proper PPE at all times; wash hands before eating or using restroom
Storage: Keep container tightly closed in a cool, dry, well-ventilated, locked area; store away from oxidizers, acids, open flames and direct sunlight
Storage Materials: Use containers made of glass, polyethylene or stainless steel; avoid copper, brass and their alloys
Special Notes: Keep out of reach of children and unauthorized personnel; label containers clearly
Exposure Limits: ACGIH TLV: 0.05 mg/m3 (as TEPP, inhalable fraction); OSHA PEL not established specifically for this compound
Engineering Controls: Local exhaust ventilation recommended; handle only in closed systems or use vapor suppression
Personal Protective Equipment (PPE): Chemical goggles, face shield, gloves (nitrile, butyl rubber), full-length clothing, chemical-resistant apron or suit
Respiratory Protection: Use NIOSH-approved respirator in absence of adequate ventilation or during emergency
Hygiene Measures: Wash hands, arms and face after handling; do not eat, drink, or smoke in work areas
Environmental Controls: Air emissions and effluent should be kept below legal limits
Appearance: Colorless to pale yellow oily liquid
Odor: Faint, unpleasant, sulfur-like
Odor Threshold: Not determined
pH: Not applicable
Boiling Point: 138°C at 1 mmHg
Melting Point: -42°C
Flash Point: 170°C (closed cup)
Flammability: Not classified as highly flammable but combustible
Vapor Pressure: 0.08 mmHg at 20°C
Vapor Density: 10.8 (air = 1)
Relative Density: 1.18–1.20 g/mL at 20°C
Solubility: Slightly soluble in water, miscible with organic solvents (acetone, alcohol, ether)
Partition Coefficient (log Pow): 2.5
Auto-ignition Temperature: Not available
Decomposition Temperature: Decomposes above 180°C
Viscosity: 6.62 cP at 20°C
Explosive Properties: Not explosive
Oxidizing Properties: Not an oxidizer
Chemical Stability: Stable under recommended storage conditions
Reactive Conditions: Avoid heat, open flame, strong acids, strong alkalis and oxidizers
Incompatible Materials: Strong oxidizing agents, acids, alkali metals, copper, brass
Decomposition Products: Produces toxic gases such as SOx, POx, CO, ethylene
Polymerization: Hazardous polymerization does not occur
Other Notes: Sensitive to light, moisture accelerates decomposition
Acute Toxicity (Oral): LD50 (rat): 1 mg/kg (highly toxic)
Acute Toxicity (Dermal): LD50 (rabbit): 10 mg/kg
Acute Toxicity (Inhalation): LC50 (rat, 4hr): 25 mg/m3
Skin Corrosion/Irritation: Causes moderate skin irritation, inflammation may occur
Serious Eye Damage/Irritation: Intense pain, redness, watering, may cause irreversible damage
Respiratory or Skin Sensitization: Not identified as a sensitizer but may aggravate asthma/bronchitis
Germ Cell Mutagenicity: Animal studies suggest possible mutagenic effects
Carcinogenicity: Not listed as carcinogenic by IARC, NTP, or OSHA
Reproductive Toxicity: Evidence of possible developmental toxicity in animal studies
Specific Target Organ Toxicity - Single Exposure: Affects nervous system, cholinesterase depression
Specific Target Organ Toxicity - Repeated Exposure: Chronic exposure gives repeated cholinesterase inhibition, neurological symptoms
Aspiration Hazard: Not classified as aspiration hazard
Ecotoxicity: Highly toxic to aquatic organisms (fish LC50 [96 hr]: 0.02 mg/L); toxic to birds and bees
Persistence/Degradability: Hydrolyzes in water over several days; breaks down in soil but some risk of groundwater contamination
Bioaccumulative Potential: Moderate, log Pow 2.5 suggests some risk
Mobility in Soil: Low to moderate, depending on local conditions
Other Adverse Effects: Risk to non-target species in treated areas, persistent toxic breakdown products possible
Waste Disposal: Use licensed chemical waste disposal contractor; incinerate material at high temperature in approved facilities
Container Disposal: Triple-rinse, puncture and send to approved hazardous waste facility; do not reuse containers
Environmental Precautions: Do not discharge to sewer, surface water or ground water
Legal Requirements: Dispose of according to national, regional and local regulations regarding hazardous waste
UN Number: UN 2783
UN Proper Shipping Name: Organophosphorus pesticide, liquid, toxic
Transport Hazard Class: 6.1 (Toxic substances)
Packing Group: I
Special Precautions for Transport: Use only UN-approved containers; ensure container integrity before loading
Environmental Hazards: Marine pollutant
Transport Label Required: Toxic, Marine Pollutant
Transport by Air: Follow IATA guidelines strictly (forbidden on passenger aircraft)
Transport by Sea: MARPOL regulated substances; check IMDG code compliance
Inventory Status: Listed on TSCA, EINECS/ELINCS, DSL, AICS, ENCS
SARA Title III: Immediate (acute) health hazard; section 313 (toxic chemical reporting required)
OSHA: Regulated as hazardous chemical
EPA: Extremely hazardous substance, emergency planning required; RQ: 10 lbs
Other regulations: Subject to local pesticide and poison control regulation; worker exposure must comply with OSHA/NIOSH guidelines; use restrictions apply for food/agriculture
Labeling Requirements: Highly toxic, apply restricted-use labeling as per government regulations; keep under lock and key
