© 2026 Sinochem Nanjing Corporation,
All Right Reserved
Product Name: O,O-Bis(4-Chlorophenyl) N-(1-Imino)Ethyl Thiophosphoramide
Synonyms: Known by some researchers as a chlorinated thiophosphoramide derivative; chemical reference in select industrial safety documents
Recommended Use: Advanced laboratory research, some specialized pesticide and synthesis applications
Manufacturer: Supply details come straight from select chemical vendors and research labs; emergency contact lines listed on original shipment documents
Chemical Family: Organo-phosphorus compounds
CAS Number: 22248-80-2
Emergency Phone: Seek Poison Control or dedicated hazardous chemicals response unit; typical labels mark direct contact information for those sites involved in large-scale handling
Address: Relevant distributor or research facility address should appear on shipment paperwork for tracking and compliance
GHS Classification: Acute Toxicity Oral (Category 2), Skin Corrosion/Irritation (Category 2), Serious Eye Damage/Irritation (Category 1), Specific Target Organ Toxicity – Single Exposure (Category 2)
Signal Word: Danger
Hazard Statements: Fatal if swallowed or in contact with skin, causes skin irritation, causes serious eye damage, can harm liver and kidney function
Precautionary Statements: Wear respiratory protection and chemical resistant gloves, wash skin thoroughly after handling, avoid breathing dust or fumes, do not eat or drink near the chemical, remove contaminated clothing immediately
Pictograms: Skull and crossbones, corrosion symbol, health hazard
Routes of Exposure: Skin contact, ingestion, inhalation present high risks; repeated exposure increases threat
Chemical Formula: C14H12Cl2N2PS
Main Ingredient: O,O-Bis(4-Chlorophenyl) N-(1-Imino)Ethyl Thiophosphoramide: 99%
Impurities: Possible traces of free amines, residual solvents from synthesis
Other Information: Complex synthesis process sometimes leaves chlorinated byproducts at trace ppm levels; supplier analysis offers detailed impurity profile
Eye Contact: Flush eyes with gently running water for 20 minutes, keeping eyelids open, immediately seek out emergency medical evaluation due to possible permanent damage
Skin Contact: Remove contaminated clothing, rinse affected skin thoroughly with cool running water and mild soap, attention required for any redness or blistering as this chemical rapidly penetrates epidermal barriers
Inhalation: Remove person to fresh air promptly, supply oxygen if breathing seems difficult, seek medical attention for persistent coughing or wheezing
Ingestion: Do not induce vomiting; rinse mouth with water, seek immediate professional care; ingesting this material leads to severe systemic toxicity
Notes for Physicians: Treat as organophosphorus poisoning, consider activated charcoal, monitor for delayed neurologic effects, observe for hepatotoxicity
Suitable Extinguishing Media: Use dry chemical, carbon dioxide, or foam for small fires; avoid water as runoff may be contaminated
Unsuitable Extinguishing Media: Avoid high-pressure water jets as they may disperse toxic materials
Specific Hazards: Burning releases toxic fumes, including phosphorus oxides, nitrogen oxides, sulfur oxides, hydrochloric acid; dense irritating smoke may aggravate rescue efforts
Protective Equipment for Firefighters: Self-contained breathing apparatus and chemical-resistant clothing needed; watch for delayed effects due to off-gassing
Firefighting Instructions: Evacuate downwind, contain contaminated runoff, local authorities should alert the community if fire risk escalates
Personal Precautions: Evacuate area, ventilate thoroughly, restrict access to authorized personnel only, wear full chemical-resistant suits and air-purifying respirators if dust risk is present
Environmental Precautions: Prevent entry into drains, sewers, or natural waterways; chemical binds to soil but remains toxic in runoff
Cleanup Methods: Absorb spill with inert materials such as vermiculite, scoop into labeled waste containers, decontaminate site with alkaline detergent wash
Decontamination: Any tools or clothing exposed should be washed with strong detergent solution, avoid using the items until decontamination certified
Waste Disposal: Dispose through a licensed hazardous waste handler familiar with organophosphorus substances
Safe Handling: Avoid generating dusts or using open containers, keep area under local exhaust ventilation, do not smoke or eat nearby, follow strict hygiene; repeated exposure increases health risk
Storage Conditions: Store in locked, segregated chemical storage cabinets, cool and dry, keep container tightly sealed, label prominently with hazard warnings
Temperature Limits: Maintain storage at room temperature or lower; avoid temperature extremes that could affect stability or packaging
Incompatibilities: Avoid storing alongside acids, bases, oxidizers, or food products; chemical is sensitive to moisture
Packaging Materials: Use only approved HDPE, glass, Teflon-lined containers; secondary containment recommended for spills
Engineering Controls: Work inside certified fume hoods, keep negative air pressure in workspaces, maintain active ventilation with particulate and gas filters
Personal Protective Equipment: Chemical splash goggles, face shields, double nitrile or neoprene gloves, full protective lab coats or coveralls, fit-tested respirators or PAPRs for dust generation tasks
Work Practices: Decontaminate surfaces often, restrict access to trained, certified personnel, maintain up-to-date safety training
Exposure Limits: No specific OSHA or ACGIH guidelines; follow general limits for organic phosphates (TWA: 0.05 mg/m³ suggested); consult internal occupational health assessments
Appearance: Pale yellow solid, fine crystalline or powder
Odor: Mild pungent, sulfurous
Odor Threshold: Not determined
pH: Not applicable in dry state
Melting Point: Range typically reported near 103–108°C
Boiling Point: Decomposes before boiling
Flash Point: Not readily flammable but may emit hazardous gas when heated
Solubility: Low in water, higher in organic solvents like acetone and DCM
Vapor Pressure: Negligible at room temperature
Partition Coefficient (log Kow): Data limited, anticipate high due to chlorinated structure
Auto-ignition Temperature: Not determined
Evaporation Rate: Not volatile under standard conditions
Flammability: May not catch fire easily, but forms noxious fumes on combustion
Density: Slightly denser than water, around 1.3 g/cm³
Viscosity: Not applicable to solid
Molecular Weight: 375.2 g/mol
Chemical Stability: Stable under recommended storage and handling conditions
Conditions to Avoid: Prolonged exposure to air, heat, sunlight, or moisture weakens compound integrity and may lead to breakdown
Incompatible Materials: Strong oxidizers, strong acids, bases, moisture, reactive metals
Decomposition Products: Phosphine gas, hydrogen chloride, nitrogen and sulfur oxides, chlorinated byproducts; all are hazardous
Reactivity: May react with strong oxidizing agents violently; keep away from reactive chemical inventories
Acute Toxicity: Swallowing small quantities produces rapid cholinergic effects, gastrointestinal distress, and systemic organ damage; skin absorption reaches bloodstream and accelerates toxicity
Skin Irritation: Causes pain, redness, burns
Eye Damage: Contact can destroy corneal tissues, induce vision loss or scarring
Respiratory Sensitization: Dust and vapor exposures trigger coughing, airway swelling, symptoms escalate to respiratory distress at high doses
Carcinogenicity: Not listed as a human carcinogen by IARC, NTP, OSHA; organophosphorus chemicals generally deserve caution
Mutagenicity: Limited genotoxicity studies, caution warranted due to phosphoramide core
Reproductive Toxicity: Animal data hints at fetal toxicity with high-dose exposures
Chronic Effects: Repeated exposure can affect liver, kidneys, blood cells; peripheral neuropathy reported in similar compounds
Medical Monitoring: Handlers benefit from regular physician evaluation targeting hepatic, renal, and neurologic health markers
Ecotoxicity: Extremely toxic to aquatic life; deaths occur fast in exposed populations even at low concentrations
Persistence and Degradability: Degrades slowly in moist soil, remains persistent in dry conditions; photolysis limited outdoors
Bioaccumulation: Likely to build up in high-trophic organisms in rivers and lakes
Mobility in Soil: Sticks strongly to organic matter, low leaching but risk persists during heavy rain and run-off events
Additional Information: Spills persist due to low volatility; remains a long-term hazard for local wildlife and groundwater
Waste Management: Segregate waste in tightly closed containers, label as acute hazardous waste
Material Disposal: Send to licensed chemical incinerators equipped for organophosphorus destruction
Contaminated Packaging: Triple-rinse, puncture, and certify for hazardous landfill or incineration
Spill Remnants: Always test cleaned surfaces, send towels and protective equipment for professional disposal
Discharge Prohibition: Direct discharges to sewers, ground, or water are forbidden under environmental safety laws
DOT Classification: Toxic solid, organic, n.o.s. (UN 2811)
IMDG: Marine pollutant, severe hazard for aquatic environments
IATA: Prohibited from passenger aircraft, cargo transport only under strict enclosure and notification rules
Packaging Instructions: UN approved chemical containers, strong outer boxing, absorbent padding, leak-proofing required
Labeling: Poison/Toxic, environment, keep away from foodstuffs and feed
Emergency Transport Info: Emergency response guides must travel with shipment; immediate notification of local authorities for leaks or spills in transit
Inventory Listing: Not widely listed on public commercial inventories; subject to notification requirements for controlled substances
Workplace Safety Laws: OSHA Hazard Communication Standard compliance, full staff training and documentation
Environmental Restrictions: Controlled under TSCA for research use, extra oversight for transportation across state or international borders
Reporting Requirements: Subject to EPA chemical inventory under Emergency Planning and Community Right to Know Act if stored above threshold; record keeping critical
Other Regulations: Severe penalties for improper disposal or mislabelled storage; local municipal rules may add requirements for organophosphorus compounds
