Wusu, Tacheng Prefecture, Xinjiang, China admin@sinochem-nanjing.com 3389378665@qq.com
Follow us:



Understanding the Safety Data of O-Methyl-O-(4-Bromo-2,5-Dichlorophenyl) Phenyl Phosphorothioate

Identification

Chemical Name: O-Methyl-O-(4-Bromo-2,5-Dichlorophenyl) Phenyl Phosphorothioate
Chemical Formula: C13H8BrCl2O2PS
Appearance: White to off-white solid or powder
Odor: Mild or slightly pungent
Common Uses: Primarily considered for research and potential pesticide formulations

Hazard Identification

Main Hazards: Acute toxicity by skin absorption, inhalation, and ingestion may occur; eye and respiratory irritation persist as significant risks.
Potential Health Effects: Contact causes redness, stinging, or burning sensations. Inhalation may lead to coughing, shortness of breath, or dizziness. Ingestion affects gastrointestinal and potentially neurological functions.
Environmental Warning: Compound shows persistence in soil and aquatic environments, posing danger to aquatic organisms and pollinators.
Signal Words: Danger or Warning, based on toxicity evidence

Composition / Information on Ingredients

Main Active: O-Methyl-O-(4-Bromo-2,5-Dichlorophenyl) Phenyl Phosphorothioate as the primary toxic component
Impurities: May include trace amounts of related organophosphate compounds and synthesis byproducts
Percentages: Concentration often exceeds 95 percent of formulated material by mass based on synthesis purity

First Aid Measures

Inhalation: Remove person to fresh air; support respiration if symptoms develop
Skin Contact: Wash affected areas thoroughly using soap and water; avoid scrubbing harmful residues into skin
Eye Contact: Rinse immediately with clean water for fifteen minutes holding eyelids apart
Ingestion: Do not induce vomiting; rinse mouth with water and seek urgent medical attention
Further Action: Medical intervention may require observation for signs of organophosphate poisoning, including muscle twitching, nausea, vomiting, and sweating

Fire-Fighting Measures

Suitable Extinguishing Media: Use dry chemical, foam, carbon dioxide, or water spray
Hazardous Combustion Products: Combustion generates toxic and corrosive vapors, such as oxides of phosphorus, sulfur dioxide, hydrogen chloride, hydrogen bromide, and phenolic compounds
Special Equipment: Responders use self-contained breathing apparatus and protective clothing to avoid exposure
Fire Response Notes: Cool containers exposed to fire with water mist; prevent runoff into water systems

Accidental Release Measures

Spill Response: Evacuate unprotected bystanders; ventilate area
Personal Protection: Wear chemical-resistant gloves, goggles, disposable coveralls, and respiratory protection
Cleanup Method: Absorb spillage with inert material such as diatomaceous earth; collect in sealed containers for disposal
Environmental Protection: Block drains to prevent contamination of watercourses; inform authorities if large quantities escape
Decontamination: Wash surfaces thoroughly with detergent after removal of solid residues

Handling and Storage

Handling Precautions: Limit handling to trained personnel using proper protective gear; work in well-ventilated areas or fume hoods
Storage Recommendations: Keep tightly sealed in original containers away from direct sunlight, heat sources, moisture, and incompatible chemicals such as oxidizers and acids
Cross-Contamination Avoidance: Store separately from consumed food, beverages, and feeds
Spill Preparedness: Maintain spill response kits and emergency washing facilities near handling zones

Exposure Controls and Personal Protection

Engineering Controls: Use local exhaust ventilation or chemical fume hoods for operations generating vapors, dust, or aerosols
Eye Protection: Safety goggles or face shields provide necessary barrier
Respiratory Protection: Approved masks with organic vapor filters should be worn in poorly ventilated spaces or high-exposure scenarios
Skin Protection: Nitrile or neoprene gloves and long-sleeve lab coats or coveralls guard against splashes
Hygiene Practices: Wash hands before eating, drinking, or smoking; remove contaminated clothing before leaving the workspace
Exposure Limits: Regulatory or recommended exposure limits are not universally standardized, but limits for organophosphate pesticides inform safety protocols

Physical and Chemical Properties

Form and Appearance: Powder or crystalline solid; color ranges white to pale yellow
Odor: Slight; not intense
Melting Point: Usually above 60°C, depending on purity
Solubility: Insoluble in water; soluble in organic solvents like acetone and chloroform
Vapor Pressure: Very low at ambient temperatures
Relative Density: Close to 1.5–1.7 g/cm³, based on molecular structure
Partition Coefficient: Typically log Kow > 3, showing strong lipophilicity and bioaccumulation potential

Stability and Reactivity

Chemical Stability: Stable in ambient conditions but hydrolyzes under strong acid or alkali
Conditions to Avoid: Prolonged heating, strong ultraviolet light, high humidity
Incompatible Materials: Strong oxidizers, acids, alkalis, and reducing agents
Hazardous Reactions: Decomposes rapidly under intense fire or strong chemical attack, producing hazardous gases
Polymerization Risk: No significant tendency

Toxicological Information

Routes of Exposure: Absorption possible through inhalation, skin, and ingestion in both laboratory and field settings
Acute Toxicity: Prominent cholinesterase inhibitor activity leads to convulsions, respiratory depression, muscle weakness, and cardiovascular effects under significant exposure
Chronic Effects: Risk for liver, kidney, and nervous system injury grows with repeated exposures; organophosphates show potential for cumulative poisoning
Typical Symptoms: Sweating, muscle twitching, nausea, headaches, labored breathing, and eventual loss of consciousness in extreme cases
Carcinogenicity and Mutagenicity: No reliable evidence for lifetime carcinogenic effects, but chronic moderate exposure to related organophosphates correlates with neurocognitive deficits in occupational surveys

Ecological Information

Aquatic Toxicity: Highly toxic to aquatic invertebrates and fish, even at levels below single milligram per liter
Persistence and Degradability: Resists rapid breakdown in soil and water; photodegrades unevenly on surfaces
Bioaccumulation Potential: Structurally persistent and lipophilic, raising the danger of food chain accumulation
Other Hazards: Poses risk to earthworms, pollinator insects, and bird populations with accidental release

Disposal Considerations

Waste Management: Classed as hazardous chemical waste and subject to special disposal procedures by authorized firms
Neutralization: Treatment possible through chemical or thermal destruction methods with environmental controls
Container Disposal: Rinsed containers need collection for chemical waste incineration
Precaution: Avoid landfill and non-secure incineration; improper disposal has caused regional environmental contamination before

Transport Information

Danger Classification: Typically falls under dangerous goods due to acute toxicity and environmental hazards
Packaging Needs: Secure, leak-proof containers; clear hazard labeling required during shipment
Handling in Transit: Keep away from food or animal feed and limit stacking to minimize spillage risk
Special Transport Risks: Inspect for leaks on receipt; accidental releases during transport have historically led to local evacuations or cleanup emergencies

Regulatory Information

Workplace Laws: Subject to hazardous substance registries and safety provisions where handled
Environmental Regulation: In some countries, restricted for agricultural or pest control purposes due to persistence and aquatic toxicity evidence
Import/Export Policy: Cross-border shipment may prompt notification, pre-authorization, or outright prohibition
Labelling: Mandatory hazard, precaution, and toxicological labeling set by chemical safety agencies